Projects per year
Personal profile
Education
- 2000-2007 Ph.D., Graduate Institute of Medicine, Taipei Medical University
- 1995-1998 M.S., Graduate institute of Medicine, Taipei Medical University
- 1983-1990 M.D., School of Medicine, Taipei Medical University
Experience
- 2021.11- Professor, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2021.11- Professor, Department of Urology, School of Medicine, College of Medicine, Taipei Medical University
- 2020.08 -2022.01 Vice Director, Research Center of Urology and Kidney, Taipei Medical University
- 2016.11-2022.11 Director, Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2014.08- Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University
- 2014.08-2017.01 Director, Department of Urology, School of Medicine, Taipei Medical University
- 2014.02-2021.10 Professor, Department of Urology, School of Medicine, Taipei Medical University
- 2010.02-2014.01 Associate Professor, Department of Urology, School of Medicine, Taipei Medical University
- 2007.02+-2010.01 Assistant Professor, Department of Urology, School of Medicine, Taipei Medical University
- 1998.08-2007.01 Instructor, Department of Urology, School of Medicine, Taipei Medical University
- 1995.07- Attending Physician, Taipei Medical University Hospital
- 1994.07-1995.06 Researcher, Taipei Medical University Hospital
- 1990.07-1994.06 Resident Physician, Taipei Medical University Hospital
Research Interests
- Prostate hyperplasia, prostate cancer
- Genitourinary cancer
- Urinary indicative surgery in Teaching Hospital Accreditation
- Reproductive medicine
- General urinary system diseases
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Collaborations and top research areas from the last five years
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Glo1-Nampt-Sirt1 Affects the Oxidative Stress and Bioenergenesis to Target Conquest of the Pd-L1 Immunosurveillance Evasion in Bladder Cancer
Chen, K.-C. (PI)
8/1/23 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Assessment of the Retrograde Potential of Combined Silybin - Metformin for Alleviating Renal Tubular Lipotoxicity Associated with Electron Transport Dysfunction Induced by Methylglyoxal via Chrebp/Srebp1 and Further Modulation of Pgc1/Sirt3
Chen, K.-C. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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開發預測高風險前列腺癌發生的生物標記及分子機轉
Chen, K.-C. (PI)
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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Will Cotreatment of Xanthohumol with Antihyperglycemics Modulate the Mitochondria Dysfunction and Reverse the Dicarbonyl Stress-Induced Diabetic Renal Lipotoxicity via Upregulated Unfold Protein Pesponse Induced Ampk -Nrf2-Are-Glo1 Pathway?
Chen, K.-C. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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In Vi Vo and in Vi Tro Screening of the Dyslipidemic Antihypertensives, Studying the Mechanism to Modulate Signaling Srebp and Ppar in the Renal Cells, and Investigating the Cotherapy with Mountain Celery Seed Aqueous Extract in Reducing Worsen Renal F(3/3)
Chen, K.-C. (PI)
8/1/18 → 7/1/19
Project: A - Government Institution › b - National Science and Technology Council
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An Antibody of the Secreted Isoform of Disintegrin and Metalloprotease 9 (sADAM9) Inhibits Epithelial–Mesenchymal Transition and Migration of Prostate Cancer Cell Lines
Jotatsu, Y., Sung, S. Y., Wu, M. H., Takeda, S., Hirata, Y., Maeda, K., Fang, S. B., Chen, K. C. & Shigemura, K., Jun 2024, In: International journal of molecular sciences. 25, 12, 6646.Research output: Contribution to journal › Article › peer-review
Open Access -
Dibenzolium induces apoptosis and inhibits epithelial-mesenchymal transition (EMT) in bladder cancer cell lines
Jotatsu, Y., Arbiser, J. L., Moriwaki, M., Hirata, Y., Takeda, S., Takada, I., Chen, K. C., Sung, S. Y. & Shigemura, K., Dec 2024, In: Scientific Reports. 14, 1, 25501.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular mechanism of ectopic lipid accumulation induced by methylglyoxal via activation of the NRF2/PI3K/AKT pathway implicates renal lipotoxicity caused by diabetes mellitus
Peng, C. C., Chen, E. C. Y., Chen, C. R., Chyau, C. C., Chen, K. C. & Peng, R. Y., 2024, In: PLoS ONE. 19, 10, p. e0306575 e0306575.Research output: Contribution to journal › Article › peer-review
Open Access -
Nicotinamide phosphoribosyltransferase modulates PD-L1 in bladder cancer and enhances immunotherapeutic sensitivity
Chen, K. C., Dhar, T., Chen, C. R., Chen, E. C. Y. & Peng, C. C., Apr 2024, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1870, 4, 167106.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
The harmful effects of overlooking acute bacterial prostatitis
Yang, Y., Shigemura, K., Maeda, K., Moriwaki, M., Chen, K. C., Nakano, Y. & Fujisawa, M., 2024, (Accepted/In press) In: International Journal of Urology. 31, 5, p. 459-463 5 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Data for: Enhanced uropathogenic Escherichia coli-induced infection in uroepithelial cells by sugar through TLR-4 and JAK/STAT1 signaling pathways
Ho, C.-H. (Contributor), Fan, C.-K. (Contributor), Wu, C.-C. (Contributor), Yu, H.-J. (Contributor), Liu, H.-T. (Contributor), Chen, K.-C. (Contributor), Liu, S.-P. (Contributor) & Cheng, P.-C. (Creator), Mendeley Data, 2019
DOI: 10.17632/n25dwn3zjj.1, https://data.mendeley.com/datasets/n25dwn3zjj
Dataset