Kang-Yun Lee

Projects

Projects per year 2012 2015 2021 2022 2023 2024

• 34 Finished

Projects per year

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• Finished

  TIGIT在免疫耐受性的轉換以及衰竭自然殺手細胞對於慢性肺阻塞病人的影響(2/3)

  Lee, K.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討在慢性阻塞性肺病由PM2.5造成肺氣腫的潛在ITIH缺失之分子機轉型 －研究 PM2.5 通過ITIH失調導致慢性阻塞性肺疾病中肺氣腫表現型(2/3)

  Lee, K.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討Withaferin A對於香菸萃取物誘導小鼠肺上皮細胞氧化傷害與發炎反應之分子機轉

  Lee, K.-Y. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 112年度【產學合作計畫-慢性呼吸道疾病-行動AI數位照護服務方案與系統之開發與實證】

  Lee, K.-Y. (PI)

  6/1/23 → 5/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• EGFR突變肺癌患者IFN-γ軸缺陷的分子機制研究

  Lee, K.-Y. (PI)

  1/1/23 → 12/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 胸腔醫學學門規劃研究推動計畫

  Lee, K.-Y. (PI)

  1/1/23 → 12/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Unravelling the Role of Tigit in the Transition of Immune Tolerance and Exhaustion Natural Killer Cells in Copd Patients (1/3)

  Lee, K.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of Pm2.5-Mediated Emphysema Phenotype through Itih Dysregulation in Copd( I )

  Lee, K.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 探討潛在天然產物對PM2.5藉氧化壓力引發細胞老化之影響

  Lee, K.-Y. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• Planning and Promotion of the Research in Pulmonology

  Lee, K.-Y. (PI)

  1/1/22 → 12/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Development of 3d Air-Liquid-Interface Lung on Lab Chips for the Studies of Air-Pollution Induced Asthma and Lung Cancer with Immunotherapy

  Lee, K.-Y. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.-Y. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討缺氧環境對Yap/Taz調控胚胎肺部之分枝與型態:纖維母細胞所扮演的角色

  Lee, K.-Y. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討HMGB1對於DCLK1調控急性呼吸窘迫症候群之第二型肺泡上皮細胞老化之角色

  Lee, K.-Y. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討在PM2.5 暴露下潛在生物標記造成不同COPD 的表現型

  Lee, K.-Y. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 胸腔醫學學門規劃研究推動計畫

  Lee, K.-Y. (PI)

  1/1/21 → 12/31/21

  Project: A - Government Institution › b - National Science and Technology Council

• 探討在PM2.5 暴露下潛在生物標記造成不同COPD 的表現型

  Lee, K.-Y. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.-Y. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 暴露PM2.5對慢性阻塞性肺病進展中臨床表現型的影響

  Lee, K.-Y. (PI)

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.-Y. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• PM2.5對慢性阻塞性肺病在肺修復和再生受損的影響-IL-17和新穎生物標記在環境PM2.5誘導COPD肺損傷的影響

  Lee, K.-Y. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.-Y. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Inter-Alpha-Trypsin Inhibitor 100%
  • Particulate Matter 100%
  • Heavy Chain 100%
  • Chronic Obstructive Lung Disease 100%
  • Inflammation 100%

• PM2.5對慢性阻塞性肺病在肺修復和再生受損的影響

  Lee, K.-Y. (PI)

  1/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.-Y. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Inter-Alpha-Trypsin Inhibitor 100%
  • Particulate Matter 100%
  • Heavy Chain 100%
  • Chronic Obstructive Lung Disease 100%
  • Inflammation 100%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.-Y. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Inter-Alpha-Trypsin Inhibitor 100%
  • Particulate Matter 100%
  • Heavy Chain 100%
  • Chronic Obstructive Lung Disease 100%
  • Inflammation 100%

• 探討非小細胞肺癌病患遠距照護醫療之研究

  Lee, K.-Y. (PI)

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• The Role of SUV39H1 in Control of Inflammatory Genes and in Chronic Inflammation of Copd

  Lee, K.-Y. (PI), Feng, P.-H. (CoI) & Chuang, H.-C. (CoI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Peripheral Blood Mononuclear Cell 100%
  • SUV39H1 100%
  • Chronic Obstructive Pulmonary Disease 100%
  • Glucocorticoid 75%
  • Systemic Inflammation 50%

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H.-C. (PI) & Lee, K.-Y. (CoI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Petrochemical Agent 100%
  • Methionine 20%
  • Ubiquitinated Protein 10%
  • Long Term Exposure 10%
  • Public Health Policy 10%

• The Effect and Mechanisms of Chemotherapy in Recruit Inflammatory Cells into Tumor Microenvironment of Lung Cancer Patients

  Feng, P.-H. (PI) & Lee, K.-Y. (CoI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Inflammatory Cell 100%
  • Neoplasm 100%
  • Tumor Microenvironment 100%
  • Lung Cancer 100%
  • Chemotherapy 100%

• TMU103-AE1-B12

  Lee, K.-Y. (PI)

  1/1/15 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism

  Lee, K.-Y. (PI)

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - National Science and Technology Council

  • Epigenetics 100%
  • Oxidative Stress 100%
  • Epigenomics 100%
  • Cell Metabolism 100%
  • SUV39H1 100%

• 慢性呼吸道疾病的氧化壓力、發炎反應、表觀遺傳學之研究

  Lee, K.-Y. (PI)

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, DNA Instability, Epigenetics and Cell Metabolism

  Lee, K.-Y. (PI)

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - National Science and Technology Council

• NF-kB以及NF-kB repressing factor (NRF) 在慢性阻塞性肺疾病引發系統性發炎之角色探討(3/3)

  Lee, K.-Y. (PI)

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - National Science and Technology Council