Projects per year
Personal profile
Education
- 2011 Ph.D. in Department of Biological Science and Technology, National Chiao Tung University
- 2007 M.S. in Department of Biological Science and Technology, National Chiao Tung University
- 2005 B.S. in Department of Biological Science and Technology, National Chiao Tung University
Experience
- 2022- Professor, Master Program in Clinical Genomics and Proteomics, Taipei Medical University
- 2022- Professor, International Ph.D. Program for Translational Science, Taipei Medical University
- 2022- Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2022- Professor, Ph.D. Program in Biotechnology Research and Development, Taipei Medical University
- 2022- Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2021-2022 Associate Professor, Master Program in Clinical Genomics and Proteomics, Taipei Medical University
- 2021-2022 Associate Professor, International Ph.D. Program for Translational Science, Taipei Medical University
- 2019-2022 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019-2022 Associate Professor, Ph.D. Program in Biotechnology Research and Development, Taipei Medical University
- 2019-2022 Assistant Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2018-2019 Assistant Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2015-2018 Assistant Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
Research Interests
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
Fingerprint
Dive into the research topics where Kai-Cheng Hsu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究－利用人工智慧與以結構為基礎策略設計與優化新穎DYRK1/CLK抑制劑(2/3)
Hsu, K.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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設計與優化新穎蛋白質激酶抑制劑應用於胰臟癌之療效與機轉探討(3/3)
Hsu, K.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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建立人工智慧模型預測新穎性TBK1抑制 劑與探討其抗發炎機轉
Hsu, K.-C. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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小分子結合位相之預測與分析
Hsu, K.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › f - Other (Funded by Government)
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設計與優化新穎蛋白質激酶抑制劑應用於胰臟癌之療效與機轉探討(2/3)
Hsu, K.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening
Lin, T. E., Chou, C. H., Wu, Y. W., Sung, T. Y., Hsu, J. Y., Yen, S. C., Hsieh, J. H., Chang, Y. W., Pan, S. L., Huang, W. J., Hsu, K. C. & Yang, C. R., Jan 13 2025, In: Journal of Chemical Information and Modeling. 65, 1, p. 378-389 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Cyclin-Dependent Kinase 8 Inhibitor E966–0530–45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo
Chou, C. H., Huang, W. J., Hsu, K. C., Hsu, J. Y., Lin, T. E. & Yang, C. R., 2025, In: International Journal of Biological Sciences. 21, 2, p. 685-707 23 p.Research output: Contribution to journal › Article › peer-review
Open Access -
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, T. E., Yen, D., HuangFu, W. C., Wu, Y. W., Hsu, J. Y., Yen, S. C., Sung, T. Y., Hsieh, J. H., Pan, S. L., Yang, C. R., Huang, W. J. & Hsu, K. C., Jun 2024, In: Protein Science. 33, 6, e5007.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress
Wu, L. H., Cheng, Y. W., Lin, F. L., Hsu, K. C., Wang, M. H., Yen, J. L., Wang, T. J., Lin, T. E., Liu, Y. C., Huang, W. J. & Hsiao, G., May 2024, In: Biomedicine and Pharmacotherapy. 174, 116538.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation
Tu, H. J., Chao, M. W., Lee, C. C., Peng, C. S., Wu, Y. W., Lin, T. E., Chang, Y. W., Yen, S. C., Hsu, K. C., Pan, S. L. & HuangFu, W. C., 2024, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 39, 1, 2418470.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Pan, S.-L. (Contributor), Hsu, K.-C. (Creator), Lin, T. E. (Creator), Lin, C.-F. (Creator), Huang, H.-L. (Contributor) & Huangfu, W.-C. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1
Dataset
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Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M.-W. (Creator), Lin, T. E. (Creator), HuangFu, W.-C. (Creator), Chang, C.-D. (Creator), Tu, H.-J. (Creator), Chen, L.-C. (Creator), Yen, S.-C. (Creator), Sung, T.-Y. (Creator), Huang, W.-J. (Creator), Yang, C.-R. (Creator), Pan, S.-L. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
Dataset
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Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C.-F. (Creator), Hsu, K.-C. (Creator), Huangfu, W.-C. (Contributor), Lin, T. E. (Creator), Huang, H.-L. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.c.4896705.v1, https://springernature.figshare.com/collections/Investigating_the_potential_effects_of_selective_histone_deacetylase_6_inhibitor_ACY1215_on_infarct_size_in_rats_with_cardiac_ischemia-reperfusion_injury/4896705/1
Dataset
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Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors
Lin, T. E. (Creator), Sung, L.-C. (Creator), Chao, M.-W. (Creator), Li, M. (Creator), Zheng, J.-H. (Creator), Sung, T.-Y. (Creator), Hsieh, J.-H. (Creator), Yang, C.-R. (Creator), Lee, H.-Y. (Creator), Cho, E.-C. (Creator) & Hsu, K.-C. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.17162118.v1, https://tandf.figshare.com/articles/journal_contribution/Structure-based_virtual_screening_and_biological_evaluation_of_novel_small-molecule_BTK_inhibitors/17162118/1
Dataset
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CCDC 2000792: Experimental Crystal Structure Determination
Hsu, M.-H. (Contributor), Hsieh, C.-Y. (Contributor), Kapoor, M. (Contributor), Chang, J.-H. (Contributor), Chu, H.-L. (Contributor), Cheng, T.-M. (Contributor), Hsu, K.-C. (Contributor), Lin, T. E. (Contributor), Tsai, F.-Y. (Contributor) & Horng, J.-C. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc254zp0, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc254zp0&sid=DataCite
Dataset