Projects per year
Personal profile
Education
- 2011 國立交通大學生物資訊及系統生物研究所博士
- 2007 國立交通大學生物資訊研究所碩士
- 2005 國立交通大學生物科技學系學士
Experience
- 2022- Professor, Master Program in Clinical Genomics and Proteomics, Taipei Medical University
- 2022- Professor, International Ph.D. Program for Translational Science, Taipei Medical University
- 2022- Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2022- Professor, Ph.D. Program in Biotechnology Research and Development, Taipei Medical University
- 2022- Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2021-2022 Associate Professor, Master Program in Clinical Genomics and Proteomics, Taipei Medical University
- 2021-2022 Associate Professor, International Ph.D. Program for Translational Science, Taipei Medical University
- 2019-2022 Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019-2022 Associate Professor, Ph.D. Program in Biotechnology Research and Development, Taipei Medical University
- 2019-2022 Assistant Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2018-2019 Assistant Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2015-2018 Assistant Professor, Ph.D. Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
Research Interests
- 生物學之生化及分子生物
- 生物資訊與醫療資訊
Fingerprint
Dive into the research topics where Kai-Cheng Hsu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
研發新穎性標的 RNA splicing 抑制劑用於治療消化道癌症之智慧型藥物設計與轉譯研究－利用人工智慧與以結構為基礎策略設計與優化新穎DYRK1/CLK抑制劑(1/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
-
設計與優化新穎蛋白質激酶抑制劑應用於胰臟癌之療效與機轉探討(2/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
-
111年度【產學合作計畫-人工智能技術應用於新穎胰臟癌藥物研發與優化(2/2)】
11/1/22 → 10/31/23
Project: A - Government Institution › b - National Science and Technology Council
-
Design and Optimization of Novel Protein Kinase Inhibitors for Pancreatic Cancer Treatment and Mechanism Investigation (1/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
-
建立以結構為基礎之藥物篩選模型並應用於研發新穎性蛋白激酶抑制劑
7/1/22 → 2/28/23
Project: A - Government Institution › b - National Science and Technology Council
-
Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma
Tseng, H. J., Banerjee, S., Qian, B., Lai, M. J., Wu, T. Y., Hsu, T. I., Lin, T. E., Hsu, K. C., Chuang, K. H., Liou, J. P. & Shih, J. C., Aug 2023, In: European Journal of Medicinal Chemistry. 256, 115459.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors
Hsu, J. Y., Hsu, K. C., Sun, C., Chou, C. H., Lin, T. E., Sung, T. Y., Tseng, H. J., Yen, S. C., Yang, C. R. & Huang, W. J., Mar 2023, In: Biomedicine and Pharmacotherapy. 159, 114258.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer
Chang, C. D., Chao, M. W., Lee, H. Y., Liu, Y. T., Tu, H. J., Lien, S. T., Lin, T. E., Sung, T. Y., Yen, S. C., Huang, S. H., Hsu, K. C. & Pan, S. L., 2023, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 38, 1, 2166039.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities
Chu, J. C., Tseng, H. J., Lee, S. B., Hsu, K. C., Hsin, L. W., Liang, R. H., Lin, T. E., Gao, N. C., Chen, L. C., Lu, W. H., Wang, A. H. J. & Huang, W. J., 2023, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 38, 1, 2212326.Research output: Contribution to journal › Article › peer-review
Open Access -
The study of a novel CDK8 inhibitor E966-0530–45418 that inhibits prostate cancer metastasis in vitro and in vivo
Ho, T. Y., Sung, T. Y., Pan, S. L., Huang, W. J., Hsu, K. C., Hsu, J. Y., Lin, T. E., Hsu, C. M. & Yang, C. R., Jun 2023, In: Biomedicine and Pharmacotherapy. 162, 114667.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
-
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, M. (Creator), Lin, T. E. (Creator), HuangFu, W. (Creator), Chang, C. (Creator), Tu, H. (Creator), Chen, L. (Creator), Yen, S. (Creator), Sung, T. (Creator), Huang, W. (Creator), Yang, C. (Creator), Pan, S. (Creator) & Hsu, K. (Creator), Taylor & Francis, 2020
DOI: 10.6084/m9.figshare.13213424.v1, https://tandf.figshare.com/articles/dataset/Identification_of_a_dual_TAOK1_and_MAP4K5_inhibitor_using_a_structure-based_virtual_screening_approach/13213424/1
Dataset
-
CCDC 2000792: Experimental Crystal Structure Determination
Hsu, M. (Contributor), Hsieh, C. (Contributor), Kapoor, M. (Contributor), Chang, J. (Contributor), Chu, H. (Contributor), Cheng, T. (Contributor), Hsu, K. (Contributor), Lin, T. E. (Contributor), Tsai, F. (Contributor) & Horng, J. (Contributor), Cambridge Crystallographic Data Centre, 2020
DOI: 10.5517/ccdc.csd.cc254zp0, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc254zp0&sid=DataCite
Dataset
-
Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors
Lin, T. E. (Creator), Sung, L. (Creator), Chao, M. (Creator), Li, M. (Creator), Zheng, J. (Creator), Sung, T. (Creator), Hsieh, J. (Creator), Yang, C. (Creator), Lee, H. (Creator), Cho, E. (Creator) & Hsu, K. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.17162118.v1, https://tandf.figshare.com/articles/journal_contribution/Structure-based_virtual_screening_and_biological_evaluation_of_novel_small-molecule_BTK_inhibitors/17162118/1
Dataset
-
Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Pan, S. (Contributor), Hsu, K. (Creator), Lin, T. E. (Creator), Lin, C. (Creator), Huang, H. (Contributor) & HuangFu, W. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1
Dataset
-
Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Lin, C. (Creator), Hsu, K. (Creator), HuangFu, W. (Contributor), Lin, T. E. (Creator), Huang, H. (Contributor) & Pan, S. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.c.4896705.v1, https://springernature.figshare.com/collections/Investigating_the_potential_effects_of_selective_histone_deacetylase_6_inhibitor_ACY1215_on_infarct_size_in_rats_with_cardiac_ischemia-reperfusion_injury/4896705/1
Dataset