Jung-Su Chang

Projects

Projects per year 2012 2012 2013 2014 2015 2019 2020 2021 2022 2023 2024

• 2 Active
• 21 Finished

Projects per year

Search results

• Active

  精準營養照護技能培訓:銜接學校教育到臨床(2/2)

  Chang, J.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 鐵過量與n-3多元不飽和脂肪酸交互作用的探索性研究:以中年肥胖之認知功能缺損為例(2/3)

  Chang, J.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Finished

  Precision Nutrition: Breaking Goals into Skills; Skills into Practice (1/2)

  Chang, J.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• An Exploratory Research of Interactive Effects of Iron and N-3 Polyunsaturated Fatty Acids Metabolism on Midlife Obesity and Cognitive Impairment (1/3)

  Chang, J.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 臺俄(RU)雙邊協議型擴充加值(add-on) 國際合作研究計畫－汞與二價金屬交互作用對肥胖及肥胖相關鐵代謝異常之關聯(3/3)

  Chang, J.

  1/1/22 → 12/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Joint Adjuvent Effects of Djulis Hull on Obesity-Related Dysmetabolic Iron Overload Syndrome and Anemia of Inflammation: Cross-Talk between Gut-Liver-Fat-Bone Marrow and Il6-Hepcidin-Ferroportin Axi

  Chang, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 臺俄(RU)雙邊協議型擴充加值(add-on) 國際合作研究計畫－汞與二價金屬交互作用對肥胖及肥胖相關鐵代謝異常之關聯(2/3)

  Chang, J.

  1/1/21 → 12/31/21

  Project: A - Government Institution › b - National Science and Technology Council

• 代謝異常鐵過量症狀與男性睪固酮合成機制:高脂高鐵飲食所扮演的角色(3/3)

  Chang, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 臺俄(RU)雙邊協議型擴充加值(add-on) 國際合作研究計畫－汞與二價金屬交互作用對肥胖及肥胖相關鐵代謝異常之關聯(1/3)

  Chang, J.

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• (教學實踐)多媒體影像應?於教學:以影像評估食物份量為例

  Chang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › d - Ministry of Education

• Dysmetabolic Iron Overload Syndrome and Testosterone Biosynthesis: Role of Fat and Iron Enriched Diet(2/3)

  Chang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Dysmetabolic Iron Overload Syndrome and Testosterone Biosynthesis: Role of Fat and Iron Enriched Diet

  Chang, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• Effects of Iron and Onion Supplementation on Advanced Glycation End Products Metabolism in Obese Rat Model

  Chang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • fatty liver 100%
  • iron 67%
  • onions 46%
  • metabolism 40%
  • advanced glycation end products 33%

• The Interactive Effects of Iron and Receptor for Advanced Glycation End Products (RAGE) on Non-alcoholic Fatty Liver Disease (NAFLD)

  Chang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Non-alcoholic Fatty Liver Disease 100%
  • Receptor for Advanced Glycation End Products 99%
  • Iron 49%
  • Fats 12%
  • Ligands 11%

• 以非酒精性脂肪肝炎動物模式探討飲食鐵對糖化終產物接受器活化的營響

  Chang, J.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 鐵質誘發巨噬細胞活化與遷移對胰島素耐受性的影響

  Chang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - National Science and Technology Council

  • Diet 100%
  • Inflammation 68%
  • Heme 64%
  • Diabetes Complications 58%
  • Anemia 49%

• 鐵質補充對第二型糖尿病的影響

  Chang, J.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Assessment of Iron Status in Overweight and Obese Adolescents

  Chang, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - National Science and Technology Council

  • Hepcidins 100%
  • Iron 87%
  • Ferritins 78%
  • Iron Overload 71%
  • Metabolic Syndrome 69%

• 由北市學童研究探討儲鐵蛋白質對巨噬細胞活化及移轉的營響

  Chang, J.

  6/1/13 → 5/31/14

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討鐵質過量對於脂肪肝病變(C型肝炎及非酒精性脂肪肝)及葡萄糖代謝的影響

  Chang, J.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 慢性肝病在台灣是一個極具挑戰性的臨床議題。肝纖維化的多重病原性是造成病患死亡 率增加的原因，而且肝纖維化往往會發展成肝癌。我們最近利用國民營養調查資料庫 (NAHSIT 2005-2008)分析國人血中鐵營養值標與代謝症候群的相關性.在全人口的分析 中，我們發現校正了血清發炎指標以及飲食的營養指標後, serum ferritin (鐵蛋白質) 高於最大三等分位的族群，得到代謝性症候群的危險對比值超過 1.6 倍. 目前並不清楚 過量的鐵蛋白質為何與代謝症候群的發生率有關。肝臟為重要的儲鐵器官但是臨床研究 也顯示過量的鐵質沉積與肝纖維化及肝癌有極大的相關性。血清中鐵蛋白質為反映體內 儲存鐵的生化質標。但是,發炎因子也會造成血清中鐵蛋白質的異常增加。證據顯示發炎 因子可以調控鐵蛋白質的基因表現量。但是慢性發炎如何造成鐵蛋白質代謝異常(組職 內沉積及釋放)? 血清中的鐵蛋白質又有何生理功能? 隨著國人代謝症候群及脂肪肝發生率的年輕化,這次研究的主題是以老鼠初代星狀肝細 胞來分析鐵蛋白質對內質網壓力機轉與肝纖維化的影響: 相關研究的主要目標為: 1. 釐清鐵蛋白質(serum ferritin)過量是否會造成星狀細胞內質網壓力增加與活化? 2. 何種鐵質(ferric, ferrous, ferritin, Apoferritin)較易增加內質網壓力? 3. 找出何種內質網壓力的轉錄因子 (ATF6,ATF4, XBP1 and CHOP)受到鐵質調控? 4. 分析鐵質誘導的內質網壓力機轉與肝臟纖維化的營響

  Chang, J.

  9/1/12 → 8/31/13

  Project: A - Government Institution › b - National Science and Technology Council

  • Ferritins 100%
  • Iron 59%
  • Liver 24%
  • Apoferritins 23%
  • Liver Cirrhosis 22%

• 探討北縣市國小及國中學生鐵營養值標與肥胖及新陳代謝症候群的關聯

  Chang, J.

  5/1/12 → 10/31/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討鐵質過量對於脂肪肝病變(C型肝炎及非酒精性脂肪肝)及葡萄糖代謝的影響

  Chang, J., Bai, C., Wu, M. & Chang, J.

  1/1/12 → 5/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Alanine Transaminase 100%
  • Hemoglobins 82%
  • Odds Ratio 66%
  • Iron 51%
  • Ferritins 42%