Projects per year
Personal profile
Education
- 1988-1992 Ph.D., Postdoctoral Research Fellow, Graduate Institute of Immunology, College of Medicine, National Taiwan University
- 1984-1988 B.S., School of Pharmacy, Taipei Medical University
Experience
- 2020.08- Deputy Dean, College of Medicine, Taipei Medical University
- 2018.02- Professor, Graduate Institute of Metabolism and Obesity Sciences, Taipei Medical University
- 2018.02- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2017.08- Professor, School of Pharmacy, Taipei Medical University
- 2016.11-2017.10 Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2014.03-2014.12 Taipei Medical University
- 2013.08- The Ph.D., Program for Neural Regenerative Medicine, Taipei Medical University
- 2012.09-2016.01 Dean, Office of Research and Development, Taipei Medical University
- 2012.08- The Ph.D. Program for Translational Medicine, Taipei Medical University
- 2010.08-2012.08 Deputy Director, College of Medicine, Taipei Medical University
- 2009.09- Professor, School of Pharmacy, Taipei Medical University
- 2007.08- Professor, Graduate Institute of Medical Sciences, Taipei Medical University, Taiwan
- 2003.09-2007.07 Director, School of Pharmacy, Taipei Medical University
- 2001.08-2004.09 Director, School of Medicine, Taipei Medical University
- 2001-2014 Chairman, Department of Pharmacology, Taipei Medical University
- 2010-2012, Deputy Dean, College of Medicine, Taipei Medical University
- 2008 Professor, Graduate Institute of Medical Sciences, Taipei Medical University
- 1999.08-2014.01 Director, School of Pharmacy, Taipei Medical University
- 1999.08-2007.07 Professor, School of Medicine, Taipei Medical University
- 1995.08-1999.07 Associate Professor, School of Medicine, Taipei Medical University
- 1993.10-1995.06 Instructor, Department & Graduate Institute of Pharmacology, National Defense Medical Center
Awards
- 2019 Research Dissertation Award - Merit Award, Taipei Medical University
- 2009 TMU Academic Research Award
- 2007-2014 MOST Reward special talents
Research Interests
- Cardiovascular Molecular Pharmacology
- Stroke
- Thrombosis and Coagulation
- Signaling
- Molecular Biology
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel Mechanisms and Effectiveness of Ginkgetin against Platelet Activation Associated with Autophagy in Humans and Facilitating Recovery from Vascular Thrombosis in Mice: the Modulation of Nf-Κb with Integrin Αiibβ3 Inside-Out and Outside-In Signals (1/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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探討SHANK3與其相關訊息傳遞蛋白: RBFA, TRIM5, and GPR68影響血小板活化及細胞自噬作用
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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吳茱萸生物鹼rutaecarpine調控血小板活化及自噬作用的機轉探討以及在自體血栓塊引起腦中風鼠的活性評估: NF-kB在無核細胞中的角色(3/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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Morin hydrate對血小板自噬作用以及對血小板活化過程中NF-κB調控路徑的影響
3/1/21 → 2/28/22
Project: C - Project of Alliance › o - Chi Mei Medical Center
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Attenuation of indoxyl sulfate–induced cell damage by cinchonidine—a Cinchona alkaloid—through the downregulation of p53 signaling pathway by promoting MDM2 cytoplasmic-nuclear shuttling in endothelial cells
Teng, R. D., Yang, C. H., Chung, C. L., Sheu, J. R. & Hsieh, C. Y., Apr 1 2023, In: Life Sciences. 318, 121477.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells
Jayakumar, T., Huang, C. J., Yen, T. L., Hsia, C. W., Sheu, J. R., Bhavan, P. S., Huang, W. C., Hsieh, C. Y. & Hsia, C. H., Aug 2022, In: Molecules. 27, 16, 5143.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-κB and ERK/p38 Signaling Molecules
Jayakumar, T., Yang, C. M., Yen, T. L., Hsu, C. Y., Sheu, J. R., Hsia, C. W., Manubolu, M., Huang, W. C., Hsieh, C. Y. & Hsia, C. H., Jun 1 2022, In: International journal of molecular sciences. 23, 11, 5889.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB
Huang, W. C., Hou, S. M., Wu, M. P., Hsia, C. H., Jayakumar, T., Hsia, C. H., Bhavan, P. S., Chung, C. L. & Sheu, J. R., Jan 1 2022, In: Molecules. 27, 2, 476.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Erratum: Auraptene, a Monoterpene Coumarin, Inhibits LTA-Induced Inflammatory Mediators via Modulating NF-κB/MAPKs Signaling Pathways (Evidence-Based Complementary and Alternative Medicine (2021) 2021 (5319584) DOI: 10.1155/2021/5319584)
Hsia, C. H., Jayakumar, T., Lu, W. J., Sheu, J. R., Hsia, C. W., Bhavan, P. S., Manubolu, M., Huang, W. C. & Chang, Y., 2022, In: Evidence-based Complementary and Alternative Medicine. 2022, 9805697.Research output: Contribution to journal › Comment/debate › peer-review
Open Access
Datasets
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Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism
Chang, C. (Contributor), Hsiung, Y. (Contributor), Jayakumar, T. (Contributor), Lin, K. (Contributor), Hsieh, C. (Creator), Trang, N. T. T. (Contributor), Lee, C. (Creator), Chen, R. (Contributor), Chang, T. (Contributor), Lu, W. (Contributor), Changou, C. A. (Creator), Lee, T. (Creator), Sheu, J. (Contributor) & Yang, C. H. (Contributor), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.14259880.v1, https://doi.org/10.6084%2Fm9.figshare.14259880.v1
Dataset
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MOESM2 of The neuroprotective effects of Tao-Ren-Cheng-Qi Tang against embolic stroke in rats
Jayakumar, T. (Contributor), Sheu, J. (Contributor), Chang, N. (Contributor), Yen, T. (Contributor), Yu, M. (Contributor), Hsu, L. (Creator), Thomas, P. A. (Creator) & Shiao, W. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3678886_d3.v1, https://doi.org/10.6084%2Fm9.figshare.c.3678886_d3.v1
Dataset
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MOESM3 of The neuroprotective effects of Tao-Ren-Cheng-Qi Tang against embolic stroke in rats
Thomas, P. A. (Creator), Yu, M. (Contributor), Chang, N. (Contributor), Shiao, W. (Creator), Hsu, L. (Creator), Yen, T. (Contributor), Jayakumar, T. (Contributor) & Sheu, J. (Contributor), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3678886_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3678886_d2.v1
Dataset
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MOESM1 of The neuroprotective effects of Tao-Ren-Cheng-Qi Tang against embolic stroke in rats
Yen, T. (Contributor), Thomas, P. A. (Creator), Shiao, W. (Creator), Sheu, J. (Contributor), Jayakumar, T. (Contributor), Chang, N. (Contributor), Yu, M. (Contributor) & Hsu, L. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3678886_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3678886_d1.v1
Dataset
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Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism
Lee, T. (Creator), Lu, W. (Creator), Changou, C. A. (Creator), Hsiung, Y. (Creator), Trang, N. T. T. (Creator), Lee, C. (Creator), Chang, T. (Creator), Jayakumar, T. (Creator), Hsieh, C. (Creator), Yang, C. H. (Creator), Chang, C. (Creator), Chen, R. (Creator), Sheu, J. (Creator) & Lin, K. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.14259880.v3, https://tandf.figshare.com/articles/dataset/Platelet_autophagic_machinery_involved_in_thrombosis_through_a_novel_linkage_of_AMPK-MTOR_to_sphingolipid_metabolism/14259880/3
Dataset