Projects per year
Personal profile
Education
- 2010 Ph.D., National Cheng-Kung University, Taiwan
- 2004 M.S., Chang-Gung University, Taiwan
- 2002 B.S., Kaohsiung Medical University, Taiwan
Experience
- 2024.02-2024.03 Acting Director, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2022- Professor, International Master Program in Medical Neuroscience, Taipei Medical University
- 2021- Vice Dean, College of Medical Science and Technology, Taipei Medical University
- 2020- Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2017-2020 Associate Professor, The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2013-2017 Assistant Professor,The Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
- 2011-2013 Postdoctoral Fellow, National Institute on Drug Abuse, NIH, U.S.A.
- 2010-2011 Postdoctoral Fellow, National Cheng-Kung University, Tainan, Taiwan
- 2009 Visiting Scholar, National Institute on Drug Abuse, NIH, , U.S.A
- 2004 Research Assistant, Chang-Gung University, Taiwan
Awards
- 2013 National Institutes of Health, Fellows Award for Research Excellence (FARE) 2013 winner
- 2010 National Cheng Kung University, Excellent Research Award
- 2009 The 17th International Symposium on Recent Advances in Cellular and Molecula Biology, Dr. Chien-Tien Hsu’ Award for Outstanding Dissertation
- 2008 National Cheng Kung University, Excellent Research Award
Research Interests
- Neuroprotection
- Brain cancer stem cell
- Drug addiction
Related Link
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Role of Mif in Regulating the Tan-Mediated T Cell Suppression and Gbm Heterogeneity( I )
Chuang, J.-Y. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Evaluating the Therapeutic Potential of Neurosteroid Metabolic Recovery and Mitochondrial Stress Relief Strategies in Traumatic Brain Injury
Chuang, J.-Y. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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巨噬細胞對膠質母細胞瘤的PDGFRA信號路徑調控的影響
Chuang, J.-Y. (PI)
7/1/25 → 2/28/26
Project: A - Government Institution › b - National Science and Technology Council
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The International Training Program for Medical Laboratory Science and Biotechnology at the College of Medical Science and Technology, Taipei Medical University
Chuang, J.-Y. (PI)
7/1/25 → 12/31/25
Project: A - Government Institution › b - National Science and Technology Council
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研究新穎性藥物Clk4抑制劑用於腦癌治療
Chuang, J.-Y. (PI)
7/1/25 → 2/28/26
Project: A - Government Institution › b - National Science and Technology Council
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Contribution of Prostaglandin E2-Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative
Shen, C. J., Chen, H. C., Lin, C. L., Thakur, A., Onuku, R., Chen, I. C., Li, H. Y., Chang, K. Y., Chuang, J. Y., Yang, W. B., Lin, H. Y., Shen, Y. R., Liou, J. P., Chang, W. C. & Hsu, T. I., Oct 13 2025, In: Advanced Science. 12, 38, e06336.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection
Banerjee, S., Hsu, Y. T., Nguyen, D. H., Yeh, S. H., Liou, K. C., Liu, J. J., Liou, J. P. & Chuang, J. Y., Feb 2025, In: Biomedicine and Pharmacotherapy. 183, 117851.Research output: Contribution to journal › Article › peer-review
Open Access -
Integration of multi-omics and single-cell transcriptome reveals mitochondrial outer membrane protein-2 (MTX-2) as a prognostic biomarker and characterizes ubiquinone metabolism in lung adenocarcinoma
Kumar, S., Wu, C. C., Wulandari, F. S., Chiao, C. C., Ko, C. C., Lin, H. Y., Ngadio, J. L., Rebecca, C., Xuan, D. T. M., Solomon, D. D., Michael, M., Kristiani, L., Chuang, J. Y., Tsai, M. C. & Wang, C. Y., 2025, In: Journal of Cancer. 16, 7, p. 2401-2420 20 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity
Liu, C. C., Yang, W. B., Chien, C. H., Wu, C. L., Chuang, J. Y., Chen, P. Y., Chu, J. M., Cheng, S. M., Qiu, L. Y., Chang, Y. C., Hwang, D. Y., Huang, C. Y., Lee, J. S. & Chang, K. Y., Jun 2024, In: Cell Death and Disease. 15, 6, 434.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia
Huang, Y. H., Lin, S. Y., Ou, L. C., Huang, W. C., Chao, P. K., Chang, Y. C., Chang, H. F., Lee, P. T., Yeh, T. K., Kuo, Y. H., Tien, Y. W., Xi, J. H., Tao, P. L., Chen, P. Y., Chuang, J. Y., Shih, C., Chen, C. T., Tung, C. W., Loh, H. H. & Ueng, S. H. & 1 others, , 2024, (Accepted/In press) In: Cell Chemical Biology. 31, 11, p. 1885-1898.e10Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)
Datasets
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MOESM2 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chen, P.-Y. (Contributor), Yang, W.-B. (Creator), Chou, S.-W. (Creator), Yang, S.-T. (Creator), Chung, P.-H. (Contributor), Chang, K.-Y. (Contributor), Liu, M.-S. (Creator), Chen, S.-H. (Contributor), Chien, C.-H. (Contributor), Hsu, T.-I. (Contributor), Chu, J.-M. (Contributor), Huang, C.-Y. (Contributor), Yang, K.-Y. (Creator), Liu, J.-J. (Creator), Chuang, J.-Y. (Creator) & Lo, W.-L. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006850.v1, https://doi.org/10.6084%2Fm9.figshare.10006850.v1
Dataset
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MOESM5 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Liu, J.-J. (Creator), Chen, P.-Y. (Contributor), Chen, S.-H. (Contributor), Chu, J.-M. (Contributor), Chien, C.-H. (Contributor), Yang, W.-B. (Creator), Lo, W.-L. (Creator), Hsu, T.-I. (Contributor), Yang, K.-Y. (Creator), Chung, P.-H. (Contributor), Chou, S.-W. (Creator), Chang, K.-Y. (Contributor), Yang, S.-T. (Creator), Chuang, J.-Y. (Creator), Huang, C.-Y. (Contributor) & Liu, M.-S. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.10006868.v1, https://doi.org/10.6084%2Fm9.figshare.10006868.v1
Dataset
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MOESM3 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Liu, J.-J. (Creator), Hsu, T.-I. (Contributor), Chou, S.-W. (Creator), Chuang, J.-Y. (Creator), Yang, W.-B. (Creator), Chen, P.-Y. (Contributor), Chen, S.-H. (Contributor), Yang, S.-T. (Creator), Chu, J.-M. (Contributor), Huang, C.-Y. (Contributor), Yang, K.-Y. (Creator), Chien, C.-H. (Contributor), Chung, P.-H. (Contributor), Lo, W.-L. (Creator), Liu, M.-S. (Creator) & Chang, K.-Y. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10006856.v1, https://doi.org/10.6084%2Fm9.figshare.10006856.v1
Dataset
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Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chien, C.-H. (Contributor), Chuang, J.-Y. (Creator), Yang, S.-T. (Creator), Yang, W.-B. (Creator), Chen, P.-Y. (Contributor), Hsu, T.-I. (Contributor), Huang, C.-Y. (Contributor), Lo, W.-L. (Creator), Yang, K.-Y. (Creator), Liu, M.-S. (Creator), Chu, J.-M. (Contributor), Chung, P.-H. (Contributor), Liu, J.-J. (Creator), Chou, S.-W. (Creator), Chen, S.-H. (Contributor) & Chang, K.-Y. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4705370.v1, https://doi.org/10.6084%2Fm9.figshare.c.4705370.v1
Dataset
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Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y.-T. (Creator), Lo, W.-L. (Creator), Chen, P.-Y. (Creator), Ko, C.-Y. (Creator), Chuang, J.-Y. (Creator), Kao, T.-J. (Creator), Yang, W.-B. (Creator), Chang, K.-Y. (Creator), Hung, C.-Y. (Creator), Kikkawa, U. (Creator), Chang, W.-C. (Creator) & Hsu, T.-I. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5916320.v1, https://springernature.figshare.com/collections/Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/5916320/1
Dataset