Projects per year
Personal profile
Education
- 2000.08-2003.02 Ph.D., Graduate Institute of Medicl Sciences, National Defense Medical Center
- 1986.08-1993.07 M.D., School of Medicine, National Defense Medical Center
Experience
- 2017.08- Professor, International Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University
- 2017.08- Professor, International Ph.D. Program for Cell Therapy and Regeneration Medicine, Taipei Medical University
- 2014.08- Professor, Graduate Institute of Clinical Medicine, Taipei Medical University
- 2013.11- Professor, Department of Gynecology and Obstetrics, School of Medicine, Taipei Medical University
- 2014 Joint Appointment Professor, Tzu Chi University
- 2014 Chair, Department of OB/ GYN, Shuang Ho Hospital, Taipei Medical University
- 2013 Deputy Superintendent, Shuang Ho Hospital, Taipei Medical University
- 2013 Joint Appointment Professor, School of Medicine, National Defense Medical Center
- 2013 Division Chief, Gynecologic Oncology, Tri-Service General Hospital
- 2017.02-2023.02 Director, Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University
- 2015.08-2021.07 Vice Superintendent, Taipei Medical University Shuang Ho Hospital
- 2013.02-2013.10 Professor, Graduate Institute of Medical Sciences, Taipei Medical University, Taiwan
- 2011.08-2013.10 Professor, School of Medicine, National Defense Medical Center
- 2010 Division Chief, Obstetrics, Tri-Service General Hospital
- 2008.08-2011.07 Associate professor, School of Medicine, National Defense Medical Center
- 2005.04-2007.03 Assistant professor, School of Medicine, National Defense Medical Center
- 2005 Visiting Scholar, Human Cancer Genetics Program, Comprehensive Cancer Center, Ohio State University
- 2002 Visiting Scholar, German Cancer Research Center (DKFZ), Heidelberg, Germany
Awards
- 2016 Who's Who in the World
- 2015 Award of Poster, Clinical Section , The 20th Taiwan Joint Cancer Conference, Taipei (PI)
- 2014 Award of Poster, Clinical Section , The 19th Taiwan Joint Cancer Conference, Taipei (PI)
- 2014 Award of Poster, Basic Section , The 19th Taiwan Joint Cancer Conference, Taipei(PI)
- 2012 Award of Technology Transfer, National Defense Medical Center, Taipei
- 2012 Award of Poster, Basic Section, The 17th Taiwan Joint Cancer Conference, Taipei (PI)
- 2012 Merit Award of ACOS (10th International Conference of the Asian Clinical Oncology Society) Seoul, Korea.
- 2011 Merit Award of ASGO (2nd Biennial Meeting of the Asian Society of Gynecologic Oncology, Seoul, Korea
- 2011 Taipei Biotech Awards, Industry-University Collaboration, Award Gold Medal Award, Taipei
- 2011 Award of Poster, Basic Section , The 16th Taiwan Joint Cancer Conference, Taipei
- 2011 Award of Research, Taiwan Association of Obstetrics and Gynecology, Chien-Tien Hsu Cancer Research Foundation, Taipei
- 2010 Award of Academic Research Category , The 7th National Innovation Award
- 2010 Award of Best Poster, Clinical Section , The 15th Taiwan Joint Cancer Conference, Taipei
- 2010 Award of Best Conference Paper, 4th Biennial Conference of the Asia Oceania research organization on Genital Infections and Neoplasia (AOGIN), India
- 2009 National Biotechnology and Medical Care Quality Award, Gold, Institute of Biotechnology and Medical Industry, Taipei
- 2009 Award of Technology Transfer, National Defense Medical Center, Taipei,
- 2009 Award of Best Research, Taiwan Association of Obstetrics and Gynecology, Chien-Tien Hsu Cancer Research Foundation, Taipei
- 2009 Award of Best Poster, Basic Section , The14th Taiwan Joint Cancer Conference, Taipei
- 2009 Award of Best Poster, Clinical Section , The14th Taiwan Joint Cancer Conference, Taipei
- 2008 Award of Best Poster, Basic Section , The13th Taiwan Joint Cancer Conference, Taipei
- 2008 Award of Best Poster, Clinical Section , The13th Taiwan Joint Cancer Conference, Taipei
- 2008 Award of Best presentation in Basic/Translational Research, The 12th Biennial Meeting of the International Gynecologic Cancer Society (IGCS) conference, Bangkok
- 2008 Award of Member in Good Standing, International Gynecologic Cancer Society.
- 2006 Afro-Asian Who’s Who
- 2005 Asia/Pacific Who’s Who
- 2004 Award of Best Theses, Graduate Institute of Medical Sciences
Research Interests
- Stem Cell
- Cancer Epigenetics & Biomarker
- Gynecologic Oncology
- Molecular Epidemiology
Related Link
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Planning and Promotion of the Research in Women and Child Health (Year 2025)
Lai, H.-C. (PI)
1/1/25 → 12/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Ovarian Cancer Patient-Derived Organoids (Ov-Pdos) as a Model for Precision Medicine and Immunotherapy
Lai, H.-C. (PI)
8/1/23 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Planning and Promotion of the Research in Women and Child Health (Year 2024)
Lai, H.-C. (PI)
1/1/24 → 12/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Fallopian Tube Organoid as a Model for the Discovery of Early Epigenetic Ovarian Cancer Biomarkers
Lai, H.-C. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Fallopian Tube Organoid as a Model for the Discovery of Early Epigenetic Ovarian Cancer Biomarkers
Lai, H.-C. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Bola-Amphiphilic Dendrimer Enhances Imatinib to Target Metastatic Ovarian Cancer via β-Catenin-HRP2 Signaling Axis
Shi, Z., Artemenko, M., Yu, W., Zhang, M., Yi, C., Chen, P., Lin, S., Bian, Z., Lian, B., Meng, F., Chen, J., Roussel, T., Li, Y., Chan, K. K. L., Ip, P. P. C., Lai, H. C., To, S. K. Y., Liu, X., Peng, L. & Wong, A. S. T., Jan 15 2025, In: ACS applied materials & interfaces. 17, 2, p. 2884-2898 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
The expression of BHLHE22 in endometrial carcinoma: Associations with mismatch repair protein expression status, tumor-infiltrating immune cells, programmed death-ligand 1 and clinical outcomes
Chen, L. Y., Chen, H. Y., Lai, H. C., Lin, S. F., Wen, K. C., Darmawi & Liew, P. L., 2025, In: Taiwanese Journal of Obstetrics and Gynecology. 64, 1, p. 110-119 10 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
The Role of SMAD7 in the Epigenetic Regulation of TGF-β Targets in the Metastasis of Ovarian Cancer
Chen, L. Y., Yang, S. Y., Chou, J. L., Chou, H. L., Yeh, C. C., Chiu, C. C., Lai, H. C., Chan, M. W. Y. & Jhang, J. S., 2025, In: Molecular Carcinogenesis. 64, 2, p. 290-304 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Active DNA Demethylase, TET1, Increases Oxidative Phosphorylation and Sensitizes Ovarian Cancer Stem Cells to Mitochondrial Complex I Inhibitor
Chen, L. Y., Shen, Y. A., Chu, L. H., Su, P. H., Wang, H. C., Weng, Y. C., Lin, S. F., Wen, K. C., Liew, P. L. & Lai, H. C., Jun 2024, In: Antioxidants. 13, 6, 735.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Correction to: In vitro drug testing using patient-derived ovarian cancer organoids (Journal of Ovarian Research, (2024), 17, 1, (194), 10.1186/s13048-024-01520-2)
Chen, L. Y., Chou, Y. T., Liew, P. L., Chu, L. H., Wen, K. C., Lin, S. F., Weng, Y. C., Wang, H. C., Su, P. H. & Lai, H. C., Dec 2024, In: Journal of Ovarian Research. 17, 1, 243.Research output: Contribution to journal › Comment/debate › peer-review
Open Access
Datasets
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Additional file 1: Table S1. of Triage of high-risk human papillomavirus-positive women by methylated POU4F3
Chen, Y.-C. (Contributor), Liao, Y.-P. (Creator), Wang, H.-C. (Creator), Lai, H.-C. (Contributor), Su, P.-H. (Contributor), Hsu, Y.-W. (Contributor), Pun, P. B. (Contributor), Chang, C.-C. (Contributor) & Huang, R.-L. (Creator), Figshare, 2015
DOI: 10.6084/m9.figshare.c.3630035_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3630035_d1.v1
Dataset
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MOESM1 of Ovarian cancer detection by DNA methylation in cervical scrapings
Wu, T.-I. (Contributor), Mao, S.-P. (Contributor), Lai, H.-C. (Contributor), Su, P.-H. (Contributor), Wu, C.-H. (Contributor) & Huang, R.-L. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.11292929.v1, https://doi.org/10.6084%2Fm9.figshare.11292929.v1
Dataset
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Additional file 1 of Complete remission of heavily treated ovarian clear cell carcinoma with ARID1A mutations after pembrolizumab and bevacizumab combination therapy: a case report
Lin, Y.-C. (Contributor), Wen, K.-C. (Creator), Sung, P.-L. (Contributor), Chou, Y.-T. (Creator), Liew, P.-L. (Contributor), Chen, L.-Y. (Contributor), Huang, R.-L. (Creator), Lai, H.-C. (Contributor) & Chang, L.-T. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.13352142.v1, https://springernature.figshare.com/articles/figure/Additional_file_1_of_Complete_remission_of_heavily_treated_ovarian_clear_cell_carcinoma_with_ARID1A_mutations_after_pembrolizumab_and_bevacizumab_combination_therapy_a_case_report/13352142/1
Dataset
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Complete remission of heavily treated ovarian clear cell carcinoma with ARID1A mutations after pembrolizumab and bevacizumab combination therapy: a case report
Lin, Y.-C. (Contributor), Wen, K.-C. (Creator), Sung, P.-L. (Contributor), Chou, Y.-T. (Creator), Liew, P.-L. (Contributor), Chen, L.-Y. (Contributor), Huang, R.-L. (Creator), Lai, H.-C. (Contributor) & Chang, L.-T. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5234313.v1, https://springernature.figshare.com/collections/Complete_remission_of_heavily_treated_ovarian_clear_cell_carcinoma_with_ARID1A_mutations_after_pembrolizumab_and_bevacizumab_combination_therapy_a_case_report/5234313/1
Dataset
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MOESM1 of Combined genetic mutations and DNA-methylated genes as biomarkers for endometrial cancer detection from cervical scrapings
Wang, H.-C. (Creator), Weng, Y.-C. (Creator), Wu, T.-I. (Contributor), Liew, P.-L. (Contributor), Lai, H.-C. (Contributor), Su, P.-H. (Contributor), Chen, C.-W. (Contributor), Liao, C.-C. (Contributor) & Huang, R.-L. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.11296943.v1, https://doi.org/10.6084%2Fm9.figshare.11296943.v1
Dataset