Personal profile
Education
- 2007 Ph.D., Institute of Molecular Medicine, National Taiwan University, Taipei, Taiwan, R.O.C.
- 2000 Master, Institute of Medical Technology, National Taiwan University, Taipei, Taiwan, R.O.C.
- 1998 Bachelor, Medical Technology. National Taiwan University, Taipei, Taiwan, R.O.C.
Experience
- 2021- Associate Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2021- Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019-2021 Assistant Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2018-2021 Assistant Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2015-2018 Assistant Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University.
- 2013-2015 Project -appointed assistant professor, Graduate Program of Cancer Cell Biology and Drug Discovery, Taipei Medical University.
- 2013 Project -appointed assistant research fellow, Graduate Program of Cancer Cell Biology and Drug Discovery, Taipei Medical University.
- 20017-2013 Postdoctoral Fellow, Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, R.O.C.
Awards
- 2013 Outstanding Research Paper Award for Postdoctoral Fellow, National Science Council
- 2012 Poster Presentation Distinguished Achievement Award, The 20th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan
- 2010 Regular Postdoctoral Fellowship Award, Academia Sinica, Institute of Biological Chemistry
- 2008 Regular Postdoctoral Fellowship Award, Academia Sinica, Institute of Biological Chemistry
- 2005 Outstanding Research Paper Award (1st place), National Taiwan University, College of Medicine
- 2005 Excellent Research Paper Award (4rd place) from Dr. Chien-Tien Hsu’s Foundation, The 13th Symposium on Recent Advances in Cellular and Molecular Biology, Taiwan.
- 2004 Poster Presentation Distinguished Achievement Award, The 12th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan
- 2003 Travel Award from Ministry of Education, Taiwan.
Research Interests
- Tumor biology
- MicroRNA
- Protein turnover
- Signal transduction
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Investigation of Mir31hg/Lnchifcar Involved Molecular Interplay in Pdac Metastasis and Microenvironment and Development Anti-Sense Oligos Based Target Therapy( III )
Chen, H.-Y. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Investigation of Mir31hg/Lnchifcar Involved Molecular Interplay in Pdac Metastasis and Microenvironment and Development Anti-Sense Oligos Based Target Therapy( II )
Chen, H.-Y. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Target Long Noncoding Rna Smyca Impairs Homologous Recombination to Inspire Anti-Tumor Immunity to Serve as a Potential Therapeutic Strategy for Cancer
Chen, H.-Y. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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研發新穎高選擇性GSK抑制劑對於胰臟癌 治療及藥理機轉探討
Chen, H.-Y. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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Long Noncoding Rna Smyca Promotes Homologous Recombination and Immune Suppression to Define a Tnbc Therapeutic Target
Chen, H.-Y. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Comparative Cardiovascular Effectiveness of Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Diabetes Mellitus
Bu, F., Wu, R., Ostropolets, A., Aminorroaya, A., Chen, H. Y., Chai, Y., Dhingra, L. S., Falconer, T., Hsu, J. C., Kim, C., Lau, W. C. Y., Man, K. K. C., Minty, E., Morales, D. R., Nishimura, A., Thangraraj, P., Van Zandt, M., Yin, C., Khera, R. & Hripcsak, G. & 1 others, , Jun 2 2026, In: Journal of the American College of Cardiology. 87, 21, p. 2963-2977 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Comparison of Cardiovascular Events in Patients Receiving Concomitant Clopidogrel and Proton Pump Inhibitors Classified by CYP2C19 Inhibitory Potency
Kim, S., Park, J., Chen, H. Y., Setiawan, C. H., Lee, H., Martin, B., Lee, K. J., Hripcsak, G., Hsu, J. C., Nagy, P., Kim, S., Nguyen, P. A., Thanh-Phuc, P., Muhtar, M. S., Hsu, M. H., Shin, W. G., You, S. C. & Seo, S. I., Mar 2026, In: Arteriosclerosis, Thrombosis, and Vascular Biology. Publish Ahead of PrintResearch output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
A machine learning framework using urinary biomarkers for pancreatic ductal adenocarcinoma prediction with post hoc validation via single-cell transcriptomics
Solomon, D. D., Ko, C. C., Chen, H. Y., Kumar, S., Wulandari, F. S., Xuan, D. T. M., Lin, H. Y., Lin, H. R., Lee, Y. K., Hsu, W. H., Pei-Ming, Y., Wang, C. Y. & Nguyen, N. U. N., Nov 1 2025, In: Briefings in Bioinformatics. 26, 6, bbaf583.Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Citations (Scopus) -
HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury
Yuan, W. C., Earl, A. S., Ma, S., Alcedo, K., Russell, J. O., Duarte, F. M., Chu, Y. T., Chang, P. C., Chen, H. Y., Chi, H. H., Zhu, Q., Rodriguez-Fraticelli, A. E., Patel, S. H., Lee, Y. R., Buenrostro, J. D. & Camargo, F. D., Jun 5 2025, In: Cell Stem Cell. 32, 6, p. 990-1005.e8Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting the TRIM21-PD-1 axis potentiates immune checkpoint blockade and CAR-T cell therapy
Shi, J., Zhang, Z., Chen, H. Y., Yao, Y., Ke, S., Yu, K., Shi, J., Xiao, X., He, C., Xiang, B., Sun, Y., Gao, M., Xing, X., Yu, H., Wang, X., Yuan, W. C., Budiarto, B. R., Chen, S. Y., Zhang, T. & Lee, Y. R. & 2 others, , Mar 5 2025, In: Molecular Therapy. 33, 3, p. 1073-1090 18 p.Research output: Contribution to journal › Article › peer-review
14 Link opens in a new tab Citations (Scopus)
Datasets
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Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival
Yan, R.-L. (Creator), Luan, C.-L. (Creator), Liao, C.-C. (Creator), Liu, L.-H. (Creator), Chen, F.-Y. (Creator), Chen, H.-Y. (Creator) & Chen, R.-H. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5990336.v1, https://springernature.figshare.com/collections/Long_noncoding_RNA_BCRP3_stimulates_VPS34_and_autophagy_activities_to_promote_protein_homeostasis_and_cell_survival/5990336/1
Dataset
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Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression
Chen, H.-Y. (Creator), Chan, S.-J. (Creator), Liu, X. (Creator), Wei, A.-C. (Creator), Jian, R.-I. (Creator), Huang, K.-W. (Creator), Lang, Y.-D. (Creator), Shih, J.-H. (Creator), Liao, C.-C. (Creator), Luan, C.-L. (Creator), Kao, Y.-T. (Creator), Chiang, S.-Y. (Creator), Hsiao, P.-W. (Creator), Jou, Y.-S. (Creator), Chen, Y. (Creator) & Chen, R.-H. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.6082528.v1, https://springernature.figshare.com/collections/Long_noncoding_RNA_Smyca_coactivates_TGF-_Smad_and_Myc_pathways_to_drive_tumor_progression/6082528/1
Dataset