Projects per year
Personal profile
Education
- 2007 Ph.D., Institute of Molecular Medicine, National Taiwan University, Taipei, Taiwan, R.O.C.
- 2000 Master, Institute of Medical Technology, National Taiwan University, Taipei, Taiwan, R.O.C.
- 1998 Bachelor, Medical Technology. National Taiwan University, Taipei, Taiwan, R.O.C.
Experience
- 2021- Associate Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2021- Associate Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2019-2021 Assistant Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University
- 2018-2021 Assistant Professor, Graduate Institute of Cancer Biology and Drug Discovery, Taipei Medical University
- 2015-2018 Assistant Professor, Ph.D Program for Cancer Molecular Biology and Drug Discovery, Taipei Medical University.
- 2013-2015 Project -appointed assistant professor, Graduate Program of Cancer Cell Biology and Drug Discovery, Taipei Medical University.
- 2013 Project -appointed assistant research fellow, Graduate Program of Cancer Cell Biology and Drug Discovery, Taipei Medical University.
- 20017-2013 Postdoctoral Fellow, Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, R.O.C.
Awards
- 2013 Outstanding Research Paper Award for Postdoctoral Fellow, National Science Council
- 2012 Poster Presentation Distinguished Achievement Award, The 20th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan
- 2010 Regular Postdoctoral Fellowship Award, Academia Sinica, Institute of Biological Chemistry
- 2008 Regular Postdoctoral Fellowship Award, Academia Sinica, Institute of Biological Chemistry
- 2005 Outstanding Research Paper Award (1st place), National Taiwan University, College of Medicine
- 2005 Excellent Research Paper Award (4rd place) from Dr. Chien-Tien Hsu’s Foundation, The 13th Symposium on Recent Advances in Cellular and Molecular Biology, Taiwan.
- 2004 Poster Presentation Distinguished Achievement Award, The 12th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan
- 2003 Travel Award from Ministry of Education, Taiwan.
Research Interests
- Tumor biology
- MicroRNA
- Protein turnover
- Signal transduction
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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探討長鏈非編碼核醣核酸Smyca促進同源重組及免疫抑制的機轉以作為三陰性乳癌的潛力治療標的
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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靶向MIR31HG/LncHIFCAR 相關分子網絡在胰腺癌轉移和腫瘤微環境的研究－探討長鏈非編碼RNA-MIR31HG/LncHIFCAR在胰臟癌轉移與腫瘤微環境的交互作用以發展反義寡核苷酸為主的治療策略(1/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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The Roles of a Novel Lncrna Linat in Regulating Tgf-Beta Signaling Dynamics and Tumor Malignancies
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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探討MIR31HG/LncHIFCAR在胰腺癌轉移和腫瘤微環境所參與的分子機轉進而發展以反譯寡核苷酸為主體的靶向治療
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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The Roles of a Novel Lncrna Linat in Regulating Tgf-Beta Signaling Dynamics and Tumor Malignancies
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Para-toluenesulfonamide, a novel potent carbonic anhydrase inhibitor, improves hypoxia-induced metastatic breast cancer cell viability and prevents resistance to αPD-1 therapy in triple-negative breast cancer
Chen, H. Y., Lin, C. E., Wu, S. C., Yang, Z. Y., Chiang, Y. F., Huang, K. C., Wang, K. L., Ali, M., Shieh, T. M., Chang, H. Y., Huang, T. C. & Hsia, S. M., Nov 2023, In: Biomedicine and Pharmacotherapy. 167, 115533.Research output: Contribution to journal › Article › peer-review
Open Access -
TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation
Chen, Y. H., Chen, H. H., Wang, W. J., Chen, H. Y., Huang, W. S., Kao, C. H., Lee, S. R., Yeat, N. Y., Yan, R. L., Chan, S. J., Wu, K. P. & Chen, R. H., Dec 2023, In: Nature Communications. 14, 1, 3050.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Correction to: Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival (Journal of Biomedical Science, (2022), 29, 1, (30), 10.1186/s12929-022-00815-0)
Yan, R. L., Luan, C. L., Liao, C. C., Liu, L. H., Chen, F. Y., Chen, H. Y. & Chen, R. H., Dec 2022, In: Journal of Biomedical Science. 29, 1, 59.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival
Yan, R. L., Luan, C. L., Liao, C. C., Liu, L. H., Chen, F. Y., Chen, H. Y. & Chen, R. H., May 10 2022, In: Journal of Biomedical Science. 29, 1, p. 30 30.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression
Chen, H. Y., Chan, S. J., Liu, X., Wei, A. C., Jian, R. I., Huang, K. W., Lang, Y. D., Shih, J. H., Liao, C. C., Luan, C. L., Kao, Y. T., Chiang, S. Y., Hsiao, P. W., Jou, Y. S., Chen, Y. & Chen, R. H., Jul 6 2022, In: Journal of Hematology and Oncology. 15, 1, p. 85 85.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus)
Datasets
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Long noncoding RNA BCRP3 stimulates VPS34 and autophagy activities to promote protein homeostasis and cell survival
Yan, R. (Creator), Luan, C. (Creator), Liao, C. (Creator), Liu, L. (Creator), Chen, F. (Creator), Chen, H. (Creator) & Chen, R. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5990336.v1, https://springernature.figshare.com/collections/Long_noncoding_RNA_BCRP3_stimulates_VPS34_and_autophagy_activities_to_promote_protein_homeostasis_and_cell_survival/5990336/1
Dataset
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Long noncoding RNA Smyca coactivates TGF-β/Smad and Myc pathways to drive tumor progression
Chen, H. (Creator), Chan, S. (Creator), Liu, X. (Creator), Wei, A. (Creator), Jian, R. (Creator), Huang, K. (Creator), Lang, Y. (Creator), Shih, J. (Creator), Liao, C. (Creator), Luan, C. (Creator), Kao, Y. (Creator), Chiang, S. (Creator), Hsiao, P. (Creator), Jou, Y. (Creator), Chen, Y. (Creator) & Chen, R. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.6082528.v1, https://springernature.figshare.com/collections/Long_noncoding_RNA_Smyca_coactivates_TGF-_Smad_and_Myc_pathways_to_drive_tumor_progression/6082528/1
Dataset