Projects per year
Personal profile
Education
- 2008 Ph.D. (Biochemical Sciences) National Taiwan University, Taipei, Taiwan
- 2003 M.S. Graduate Institute of Biochemistry, National Chung Hsing University
- 2000 B.S., Department of Food Science, Tunghai University
Experience
- 2022.08- Vice Dean, Office of Research and Development, Taipei Medical University
- 2019- Assistant Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2017- Assistant Professor, Ph.D. Program for Translational Medicine, Taipei Medical University
- 2013-2017 Assistant Professor, Ph.D. Program for Translational Medicine, Taipei Medical University
Research Interests
- DNA mimic protein
- Protein-DNA interaction
- Virus–host interaction
- Structural biology
Related Link
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Investigating the Gene Regulation and Pore Forming Mechanism of Ahpnd Toxins Piravp and Pirbvp from the Perspective of Structural Biology
Wang, H.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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受石斑魚虹彩病毒(grouper iridovirus, GIV)誘導表現的點帶石斑魚CC趨化素EcSCYA102/103/116/118之免疫功能鑑定
Wang, H.-C. (PI)
1/1/24 → 12/31/24
Project: C - Project of Alliance › l - National Taiwan Ocean University
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Functional Study of Phytoplasma Phyl1 Interacting Proteins Using Structural and Proteomic Approaches – Stage 2 Study( III )
Wang, H.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Functional Study of Phytoplasma Phyl1 Interacting Proteins Using Structural and Proteomic Approaches – Stage 2 Study( II )
Wang, H.-C. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Exploring the Activation Mechanism and Neutralization Strategy of the Ahpnd-Causing Toxins Piravp and Pirbvp
Wang, H.-C. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Ribonuclease 1 Induces T-Cell Dysfunction and Impairs CD8+ T-Cell Cytotoxicity to Benefit Tumor Growth through Hijacking STAT1
Yang, W. H., Huang, B. Y., Rao, H. Y., Ye, P., Chen, B., Wang, H. C., Chung, C. H., Wu, H. H., Yen, H. R., Wang, S. C., Cha, J. H., Yan, X., Yang, M. H. & Hung, M. C., 2025, (Accepted/In press) In: Advanced Science. 12, 13, 2404961.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular Insights into MpAGO1 and Its Regulatory miRNA, miR11707, in the High-Temperature Acclimation of Marchantia polymorpha
Hong, S. F., Wei, W. L., Pan, Z. J., Yu, J. Z., Cheng, S., Hung, Y. L., Tjita, V., Wang, H. C., Komatsu, A., Nishihama, R., Kohchi, T., Chen, H. M., Chen, W. C., Lo, J. C., Chiu, Y. H., Yang, H. C., Lu, M. Y., Liu, L. Y. D. & Lin, S. S., Oct 3 2024, In: Plant & cell physiology. 65, 9, p. 1414-1433 20 p.Research output: Contribution to journal › Article › peer-review
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Structural insights into the molecular mechanism of phytoplasma immunodominant membrane protein
Liu, C. Y., Cheng, H. P., Lin, C. P., Liao, Y. T., Ko, T. P., Lin, S. J., Lin, S. S. & Wang, H. C., May 1 2024, In: IUCrJ. 11, Pt 3, p. 384-394 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The QS regulator AphBvp promotes expression of the AHPND PirAvp and PirBvp toxins and may enhance virulence under acidic conditions
Lin, S. J., Le, P. T., Chang, Y. C., Liu, C. Y., Chen, Y. H., Wu, C. J., Huang, H. J., Hsu, K. C., Ko, T. P., Tien, N. Y., Wang, H. C., Lo, C. F. & Wang, H. C., Dec 2024, In: International Journal of Biological Macromolecules. 283, 137563.Research output: Contribution to journal › Article › peer-review
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A bacterial binary toxin system that kills both insects and aquatic crustaceans: Photorhabdus insect-related toxins A and B
Wang, H. C., Lin, S. J., Wang, H. C., Kumar, R., Le, P. T. & Leu, J. H., May 2023, In: PLoS Pathogens. 19, 5, e1011330.Research output: Contribution to journal › Review article › peer-review
Open Access7 Citations (Scopus)
Datasets
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3WDG : Staphylococcus aureus UDG / UGI complex
Wang, H.-C. (Contributor), Ko, T.-P. (Contributor) & Wang, A.H.-J. (Contributor), RCSB-PDB, 2014
DOI: 10.2210/pdb3wdg/pdb, https://www.rcsb.org/structure/3WDG
Dataset
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3WDF : Staphylococcus aureus UDG
Wang, H.-C. (Contributor), Ko, T.-P. (Contributor) & Wang, A.H.-J. (Contributor), RCSB-PDB, 2014
DOI: 10.2210/pdb3wdf/pdb, https://www.rcsb.org/structure/3WDF
Dataset
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3W1O : Neisseria DNA mimic protein DMP12
Wang, H.-C. (Contributor), Wu, M.-L. (Contributor), Ko, T.-P. (Contributor) & Wang, A.H.-J. (Contributor), RCSB-PDB, 2013
DOI: 10.2210/pdb3w1o/pdb, https://www.rcsb.org/structure/3W1O
Dataset
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3WX4 : CRYSTAL STRUCTURE of T4 PHAGE ARN PROTEIN
Ho, C.-H. (Contributor), Wang, H.-C. (Contributor), Ko, T.-P. (Contributor) & Wang, A.H.-J. (Contributor), RCSB-PDB, 2014
DOI: 10.2210/pdb3wx4/pdb, https://www.rcsb.org/structure/3WX4
Dataset
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3VJZ : Crystal structure of the DNA mimic protein DMP19
Wang, H.-C. (Contributor), Wang, A.H.-J. (Contributor) & Ko, T.-P. (Contributor), RCSB-PDB, 2012
DOI: 10.2210/pdb3vjz/pdb, https://www.rcsb.org/structure/3VJZ
Dataset