Projects per year
Personal profile
Education
- 2009 PhD, Institute of Basic Medical Sciences, National Cheng-Kung University, Taiwan
- 2003 MS, Institute of Biomedical Sciences, National Sun Yat-Sen University, Taiwan
- 2000 BS, Department of Biology, Kaohsiung Medical University, Taiwan
Experience
- 2020- Associate Professor, Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taiwan
- 2016-2020 Assistant Professor, Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taiwan
- 2014-2016 Research Fellow, Ph.D. Program for Neural Regenerative Medicine, College of Medical Science and Technology, Taipei Medical University, Taiwan
- 2011-2013 Postdoctoral fellow, Department of Pharmacology, Kyoto University, Japan (Dragon Gate Program supported by NSC, Taiwan)
- 2011-2011 Postdoctoral fellow, Institute of Medical Sciences, Taipei Medical University, Taiwan
- 2010-2011 Postdoctoral fellow, Institute of Pharmacology, National Cheng-Kung University, Taiwan
- 2009-2010 Postdoctoral fellow, Center for Gene Regulation and Signal Transduction Research, National Cheng-Kung University, Taiwan
Awards
- 2011 Excellent Research Award, 2011 International symposium on cell signaling and gene regulation, Taiwan
- 2008 Excellent Research Award, 16th Symposium on Recent Advances in Cellular and Molecular Biology, Taiwan
- 2008 Excellent Research Award, 2008 International symposium on cell signaling and gene regulation, Taiwan
Research Interests
- Neuronal inflammation and Neuroglia biology
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Collaborations and top research areas from the last five years
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Projects
- 15 Finished
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Investigating the Effects of Peripheral Ptx3 Blockade on Alzheimer'S Disease Therapy (Ii)
Ko, C.-Y. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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探討癌症相關纖維母細胞在多形性膠質母細胞瘤發展過程中的影響
Ko, C.-Y. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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Investigating the Effects of Peripheral Ptx3 Blockage for Alzheimer'S Disease Therapy
Ko, C.-Y. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Znf179在神經損傷與退化的神經發炎中之角色探討
Ko, C.-Y. (PI)
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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Investigation of Astrocytic Cebpd-Regulated Mirnas and Their Effects on Angiogenesis during Neuroinflammation (Ii)
Ko, C.-Y. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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Exploring neuron-specific steroid synthesis and DHEAS therapy in Alzheimer's disease
Lin, H. Y., Feng, Y. H., Kao, T. J., Chen, H. C., Chen, G. Y., Ko, C. Y. & Hsu, T. I., Oct 2024, In: Journal of Steroid Biochemistry and Molecular Biology. 243, 106585.Research output: Contribution to journal › Article › peer-review
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Identification, biological evaluation, and crystallographic analysis of coumestrol as a novel dual-specificity tyrosine-phosphorylation-regulated kinase 1A inhibitor
Peng, C. H., Hwang, T. L., Hung, S. C., Tu, H. J., Tseng, Y. T., Lin, T. E., Lee, C. C., Tseng, Y. C., Ko, C. Y., Yen, S. C., Hsu, K. C., Pan, S. L. & HuangFu, W. C., Dec 2024, In: International Journal of Biological Macromolecules. 282, 136860.Research output: Contribution to journal › Article › peer-review
Open Access -
Astrocytic Cebpd Regulates Pentraxin 3 Expression to Promote Fibrotic Scar Formation After Spinal Cord Injury
Wang, S. M., Hsu, J. Y. C., Ko, C. Y., Wu, H. E., Hsiao, Y. W. & Wang, J. M., 2023, (Accepted/In press) In: Molecular Neurobiology. 60, 4, p. 2200-2208 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression
Feng, Y. H., Lim, S. W., Lin, H. Y., Wang, S. A., Hsu, S. P., Kao, T. J., Ko, C. Y. & Hsu, T. I., May 2022, In: Journal of Steroid Biochemistry and Molecular Biology. 219, p. 106067 106067.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
CCAAT/Enhancer-Binding Protein Delta Regulates Glioblastoma Survival through Catalase-Mediated Hydrogen Peroxide Clearance
Lin, H. Y., Lim, S. W., Hsu, T. I., Yang, W. B., Huang, C. C., Tsai, Y. T., Chang, W. C. & Ko, C. Y., 2022, In: Oxidative Medicine and Cellular Longevity. 2022, 4081380.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus)
Datasets
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Additional file 1: of Suberoylanilide hydroxamic acid represses glioma stem-like cells
Chang, K.-Y. (Creator), Wang, J.-Y. (Creator), Chuang, J.-Y. (Creator), Ko, C.-Y. (Contributor), Hsu, T.-I. (Contributor), Chang, W.-C. (Creator), Yeh, S.-H. (Contributor), Liou, J.-P. (Creator), Liu, J.-J. (Contributor) & Hsu, C.-C. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3596465_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3596465_d1.v1
Dataset
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Suberoylanilide hydroxamic acid represses glioma stem-like cells
Hsu, C.-C. (Contributor), Chang, W.-C. (Creator), Hsu, T.-I. (Contributor), Liu, J.-J. (Contributor), Yeh, S.-H. (Contributor), Wang, J.-Y. (Creator), Liou, J.-P. (Creator), Ko, C.-Y. (Contributor), Chang, K.-Y. (Creator) & Chuang, J.-Y. (Creator), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3596465.v1, https://doi.org/10.6084%2Fm9.figshare.c.3596465.v1
Dataset
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CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation
Wang, S.-M. (Creator), Lin, H.-Y. (Creator), Chen, Y.-L. (Contributor), Hsu, T.-I. (Contributor), Chuang, J.-Y. (Creator), Kao, T.-J. (Contributor) & Ko, C.-Y. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4575326.v1, https://doi.org/10.6084%2Fm9.figshare.c.4575326.v1
Dataset
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Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation
Tsai, Y.-T. (Creator), Lo, W.-L. (Creator), Chen, P.-Y. (Creator), Ko, C.-Y. (Creator), Chuang, J.-Y. (Creator), Kao, T.-J. (Creator), Yang, W.-B. (Creator), Chang, K.-Y. (Creator), Hung, C.-Y. (Creator), Kikkawa, U. (Creator), Chang, W.-C. (Creator) & Hsu, T.-I. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5916320.v1, https://springernature.figshare.com/collections/Reprogramming_of_arachidonate_metabolism_confers_temozolomide_resistance_to_glioblastoma_through_enhancing_mitochondrial_activity_in_fatty_acid_oxidation/5916320/1
Dataset
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Additional file 1: of CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation
Chen, Y.-L. (Contributor), Chuang, J.-Y. (Creator), Wang, S.-M. (Creator), Kao, T.-J. (Contributor), Lin, H.-Y. (Creator), Ko, C.-Y. (Contributor) & Hsu, T.-I. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.8866895.v1, https://doi.org/10.6084%2Fm9.figshare.8866895.v1
Dataset