Projects per year
Personal profile
Education
- 2000-2005 Ph.D., Graduate Institute of Toxicology, College of Medicine, National Taiwan University
- 1998-2000 M.S., Graduate Institute of Toxicology, College of Medicine, National Taiwan University
- 1994-1998 B.S., Department of Plant Pathology and Microbiology, College of Medicine, National Taiwan University
Experience
- 2024.04- Director, Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University
- 2022.02- Professor, Department of Physiology, School of Medicine, Taipei Medical University
- 2017.02-2022.01 Associate Professor, Department of Physiology, School of Medicine, Taipei Medical University
- 2012.09-2017.01 Assistant Professor, Department of Physiology, School of Medicine, Taipei Medical University
- 2012.08-2012.08 Assistant Researcher, Department of Physiology, School of Medicine, Taipei Medical University
Research Interests
- Physiology
- Environmental Toxicology
- NanoToxicology
- Safety Toxicology
- Cardiovascular Physiology
Related Link
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Study the Pathophysiology Role of Retinal Endothelial Cell Specific Protein Melanopsin and Gnaz upon the Dark and Blue-Light Condition, as Well as Their Clinical Application
Li, C.-H. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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探討奈米塑膠活化脂肪細胞，促進脂肪細胞激素分泌之毒理效應
Li, C.-H. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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Ahr Defect Changes Integrin Signaling in Retinal Pigment Epithelial Cells, Resulting Retinal Inflammation and Function Impairment( III )
Li, C.-H. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Explore the Pathophysiology Role of Vascular Endothelial Cell and Adam 17 during Blue Light-Induced Retinopathy, and the Therapeutic Strategy.
Li, C.-H. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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探討組織蛋白去乙醯酶異構酵素參與視網膜微血管新生和血視網膜屏障滲漏之訊息路徑
Li, C.-H. (PI)
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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Maintaining KEAP1 levels in retinal pigment epithelial cells preserves their viability during prolonged exposure to artificial blue light
Li, C. H., Yang, T. M., Fitriana, I., Fang, T. C., Wu, L. H., Hsiao, G. & Cheng, Y. W., Nov 2024, In: Journal of Photochemistry and Photobiology B: Biology. 260, 113037.Research output: Contribution to journal › Article › peer-review
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Activation of aryl hydrocarbon receptor by azatyrosine-phenylbutyric hydroxamide inhibits progression of diabetic retinopathy mice
Fitriana, I., Wu, C. H., Hsu, T. J., Chan, Y. J., Li, C. H., Lee, C. C., Hsiao, G. & Cheng, Y. W., Sept 2023, In: Biochemical Pharmacology. 215, 115700.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Blue light exposure collapses the inner blood-retinal barrier by accelerating endothelial CLDN5 degradation through the disturbance of GNAZ and the activation of ADAM17
Chan, Y. J., Hsiao, G., Wan, W. N., Yang, T. M., Tsai, C. H., Kang, J. J., Lee, Y. C., Fang, T. C., Cheng, Y. W. & Li, C. H., Dec 2023, In: Fluids and Barriers of the CNS. 20, 1, 31.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Association Between DPP-4 Inhibitors and Events of Colorectal and Liver Cancers in Patients With Diabetes Receiving Second-Line Agents: A Nested Case-Control Study
Chou, C. L., Juan, S. H., Li, C. H., Chen, H. H., Kao, C. C., Chen, L. Y., Chien, L. N. & Fang, T. C., May 6 2022, In: Frontiers in Oncology. 12, 840142.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Benefits of Valsartan and Amlodipine in Lipolysis through PU.1 Inhibition in Fructose-Induced Adiposity
Chou, C. L., Li, C. H. & Fang, T. C., Sept 2022, In: Nutrients. 14, 18, 3759.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)
Datasets
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Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Chan, Y.-J. (Contributor), Cheng, Y.-W. (Creator), Liao, P.-L. (Contributor), Li, C.-H. (Creator), Lin, F.-L. (Contributor), Ho, J.-D. (Contributor), Chen, C.-Y. (Contributor) & Tsai, C.-H. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5263303.v1, https://doi.org/10.6084%2Fm9.figshare.c.5263303.v1
Dataset
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Additional file 1 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Ho, J.-D. (Contributor), Lin, F.-L. (Contributor), Tsai, C.-H. (Contributor), Liao, P.-L. (Contributor), Chan, Y.-J. (Contributor), Cheng, Y.-W. (Creator), Li, C.-H. (Creator) & Chen, C.-Y. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.13550758.v1, https://doi.org/10.6084%2Fm9.figshare.13550758.v1
Dataset
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Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
Chen, C.-Y. (Contributor), Liao, P.-L. (Contributor), Tsai, C.-H. (Contributor), Chan, Y.-J. (Contributor), Cheng, Y.-W. (Creator), Hwang, L.-L. (Creator), Lin, K.-H. (Contributor), Yen, T.-L. (Contributor) & Li, C.-H. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4701761.v1, https://springernature.figshare.com/collections/Inhaled_gold_nanoparticles_cause_cerebral_edema_and_upregulate_endothelial_aquaporin_1_expression_involving_caveolin_1_dependent_repression_of_extracellular_regulated_protein_kinase_activity/4701761/1
Dataset
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MOESM1 of Inhaled gold nanoparticles cause cerebral edema and upregulate endothelial aquaporin 1 expression, involving caveolin 1 dependent repression of extracellular regulated protein kinase activity
Chen, C.-Y. (Contributor), Liao, P.-L. (Contributor), Tsai, C.-H. (Contributor), Chan, Y.-J. (Contributor), Cheng, Y.-W. (Contributor), Hwang, L.-L. (Contributor), Lin, K.-H. (Contributor), Yen, T.-L. (Contributor) & Li, C.-H. (Contributor), Unknown Publisher, Oct 16 2019
DOI: 10.6084/m9.figshare.9994028.v1, https://springernature.figshare.com/articles/MOESM1_of_Inhaled_gold_nanoparticles_cause_cerebral_edema_and_upregulate_endothelial_aquaporin_1_expression_involving_caveolin_1_dependent_repression_of_extracellular_regulated_protein_kinase_activity/9994028/1
Dataset
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Additional file 2 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation
Li, C.-H. (Creator), Ho, J.-D. (Contributor), Chan, Y.-J. (Contributor), Chen, C.-Y. (Contributor), Cheng, Y.-W. (Creator), Lin, F.-L. (Contributor), Liao, P.-L. (Contributor) & Tsai, C.-H. (Contributor), Figshare, 2021
DOI: 10.6084/m9.figshare.13550761.v1, https://doi.org/10.6084%2Fm9.figshare.13550761.v1
Dataset