Projects per year
Projects
- 20 Finished
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Finished
透過活體動物高轉移乳癌模式及全基因 剔除研究平台（Genome-scale CRISPR- Cas9 Knockout，GeCKO）評估GSDMC基因 作為乳癌轉移標靶治療有效性探討
Lee, C.-H. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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利用全基因組剔除研究平台(Genome- Scale CRISPR Knock-Out，GeCKO)篩選 CDC20基因並以CRISPR/Cas9基因剪輯探 討其在雙打擊瀰漫性大B細胞瘤(DHL)上 抗癌機制
Lee, C.-H. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Anti-Cancer Mechanism of Targeting Udp-Glucuronosyltransferase 2b7 (Ugt-2b7) through Multigenerational Breast Cancer Metastasis Animal Model and Genome-Wide Crispr-Cas9 Knock out (Gecko) Screening Model.
Lee, C.-H. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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建立SARS-CoV-2 nsp5內切酶活性冷光檢測平台篩選抗病毒藥物-以Omicron變異株為例
Lee, C.-H. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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以活體肺轉移研究平台與全基因剔除模式(GeCKO)探討未分化甲狀腺癌轉移與基因調控-以TNFRSF19、CTDP1基因開發抗甲狀腺癌策略為例
Lee, C.-H. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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Development of a Novel Therapeutic Strategy for Triple Negative Breast Cancers (Tnbc) through Targeting Udp-Glucuronosyltransferase 2b7 (Ugt2b7)( III )
Lee, C.-H. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Development of a Novel Therapeutic Strategy for Triple Negative Breast Cancers (Tnbc) through Targeting Udp-Glucuronosyltransferase 2b7 (Ugt2b7)( II )
Lee, C.-H. (PI)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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以CRISPR/Cas9建立exosome-free研究模式探討外泌體(exosome)調控三陰性乳癌轉移機制
Lee, C.-H. (PI)
7/1/21 → 2/28/22
Project: A - Government Institution › b - National Science and Technology Council
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以CRISPR/cas9開發三陰性乳癌轉移中iPS相關基因作為標靶研究平台
Lee, C.-H. (PI)
7/1/21 → 2/28/22
Project: A - Government Institution › b - National Science and Technology Council
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Development of a Novel Therapeutic Strategy for Triple Negative Breast Cancers (Tnbc) through Targeting Udp-Glucuronosyltransferase 2b7 (Ugt2b7)( I )
Lee, C.-H. (PI)
8/1/20 → 7/1/21
Project: A - Government Institution › b - National Science and Technology Council
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以單點基因編輯(single base editing)作為KRAS基因突變校正之抗癌治療研究
Lee, C.-H. (PI)
7/1/20 → 2/1/21
Project: A - Government Institution › b - National Science and Technology Council
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以新穎mito-FD-CRISPR/Cas9系統開發粒線體基因編輯模式
Lee, C.-H. (PI)
7/1/20 → 2/1/21
Project: A - Government Institution › b - National Science and Technology Council
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以NIADS優化TNBC藥物篩檢平台並以基因編輯技術探討IL6R及IL7R在乳癌轉移所扮演的角色
Lee, C.-H. (PI)
7/1/19 → 2/1/20
Project: A - Government Institution › b - National Science and Technology Council
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以基因剪輯技術(CRISPR/Cas9)應用於費城染色體為標靶之慢性骨髓性白血病治療
Lee, C.-H. (PI)
7/1/17 → 2/28/18
Project: A - Government Institution › b - National Science and Technology Council
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Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors
Lee, C.-H. (PI) & Ho, Y.-S. (CoI)
8/1/15 → 7/31/16
Project: A - Government Institution › b - National Science and Technology Council
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Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.
Wu, C.-H. (PI), Ho, Y.-S. (CoI) & Lee, C.-H. (CoI)
8/1/15 → 7/31/16
Project: A - Government Institution › c - Ministry of Health and Welfare
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Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors
Lee, C.-H. (PI)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.
Wu, C.-H. (PI), Ho, Y.-S. (CoI) & Lee, C.-H. (CoI)
5/1/14 → 7/30/15
Project: A - Government Institution › c - Ministry of Health and Welfare
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Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors
Lee, C.-H. (PI)
8/1/13 → 7/31/14
Project: A - Government Institution › b - National Science and Technology Council
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Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.
Wu, C.-H. (PI), Ho, Y.-S. (CoI) & Lee, C.-H. (CoI)
5/1/12 → 4/30/13
Project: A - Government Institution › c - Ministry of Health and Welfare