Projects per year
Personal profile
Education
- 2004-2010 Ph.D., Graduate Institute of Medical Sciences, Taipei Medical University, Taiwan
- 2002-2004 M.S., School of Pharmacy, Taipei Medical University
- 1994-1998 B.S., College of Pharmacy , China Medical University
Experience
- 2018.08- Associate Professor, School of Pharmacy, Taipei Medical University
- 2013.08-2018.07 Assistant professor, School of Medicine, Taipei Medical University
- 2011.09-2013.07 Postdoctoral Research Fellow, Taipei Medical University
Research Interests
- Free radical biology, protein modification, translational research
Related Link
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Projects
- 22 Finished
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銀杏素改善自體血栓栓塞性腦中風引起微小神經膠細胞和神經元活化的神經再生作用
3/1/22 → 2/28/23
Project: C - Project of Alliance › o - Chi Mei Medical Center
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探討SHANK3與其訊息傳遞蛋白: RBFA, TRIM5, and GPR68影響缺血性中風相關之發炎調控
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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A Breakthrough Therapeutic Strategy against Ischemic Brain Injury- the Senolytic Treatment Dramatically Expands Therapeutic Time Window of Acute Ischemic Stroke
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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Esculetin對改善周邊血管平滑肌細胞增生及大腦血管內皮細胞發炎反應的活性評估及機轉探討
3/1/21 → 2/28/22
Project: C - Project of Alliance › o - Chi Mei Medical Center
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利用蛋白質體學研究方式探討glyoxalase 1改善急性缺血性腦中風造成血腦障壁傷害之作用機制
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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Attenuation of indoxyl sulfate–induced cell damage by cinchonidine—a Cinchona alkaloid—through the downregulation of p53 signaling pathway by promoting MDM2 cytoplasmic-nuclear shuttling in endothelial cells
Teng, R. D., Yang, C. H., Chung, C. L., Sheu, J. R. & Hsieh, C. Y., Apr 1 2023, In: Life Sciences. 318, 121477.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells
Jayakumar, T., Huang, C. J., Yen, T. L., Hsia, C. W., Sheu, J. R., Bhavan, P. S., Huang, W. C., Hsieh, C. Y. & Hsia, C. H., Aug 2022, In: Molecules. 27, 16, 5143.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Anti-Inflammatory Mechanism of An Alkaloid Rutaecarpine in LTA-Stimulated RAW 264.7 Cells: Pivotal Role on NF-κB and ERK/p38 Signaling Molecules
Jayakumar, T., Yang, C. M., Yen, T. L., Hsu, C. Y., Sheu, J. R., Hsia, C. W., Manubolu, M., Huang, W. C., Hsieh, C. Y. & Hsia, C. H., Jun 1 2022, In: International journal of molecular sciences. 23, 11, 5889.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Metformin Serves as a Novel Drug Treatment for Arterial Thrombosis: Inhibitory Mechanisms on Collagen-Induced Human Platelet Activation
Chang, Y., Huang, W. C., Hsu, C. Y., Hsia, C. W., Jayakumar, T., Hsieh, C. Y., Lu, W. J. & Chang, C. C., Aug 2022, In: Applied Sciences (Switzerland). 12, 15, 7426.Research output: Contribution to journal › Article › peer-review
Open Access -
Yohimbine, an α2-Adrenoceptor Antagonist, Suppresses PDGF-BB-Stimulated Vascular Smooth Muscle Cell Proliferation by Downregulating the PLCγ1 Signaling Pathway
Chiu, C. W., Hsieh, C. Y., Yang, C. H., Tsai, J. H., Huang, S. Y. & Sheu, J. R., Jul 2022, In: International journal of molecular sciences. 23, 14, 8049.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism
Chang, C. (Contributor), Hsiung, Y. (Contributor), Jayakumar, T. (Contributor), Lin, K. (Contributor), Hsieh, C. (Creator), Trang, N. T. T. (Contributor), Lee, C. (Creator), Chen, R. (Contributor), Chang, T. (Contributor), Lu, W. (Contributor), Changou, C. A. (Creator), Lee, T. (Creator), Sheu, J. (Contributor) & Yang, C. H. (Contributor), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.14259880.v1, https://doi.org/10.6084%2Fm9.figshare.14259880.v1
Dataset
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Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism
Lee, T. (Creator), Lu, W. (Creator), Changou, C. A. (Creator), Hsiung, Y. (Creator), Trang, N. T. T. (Creator), Lee, C. (Creator), Chang, T. (Creator), Jayakumar, T. (Creator), Hsieh, C. (Creator), Yang, C. H. (Creator), Chang, C. (Creator), Chen, R. (Creator), Sheu, J. (Creator) & Lin, K. (Creator), Taylor & Francis, 2021
DOI: 10.6084/m9.figshare.14259880.v3, https://tandf.figshare.com/articles/dataset/Platelet_autophagic_machinery_involved_in_thrombosis_through_a_novel_linkage_of_AMPK-MTOR_to_sphingolipid_metabolism/14259880/3
Dataset