Projects per year
Personal profile
Education
Experience
- 2019.08- Chair Professor, Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
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Dive into the research topics where Che-Kun Shen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Healthy Longevity: Anti-Aging and Anti-Disease by a Genetically Modified Hematopoietic Blood System( I )
Shen, C.-K. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Basic and Translational Studies of Neurodegenerative Diseases with Tdp-43 Proteinopathies( I )
Shen, C.-K. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Neuronal Function of the Rna-Binding Protein Tdp-43 and Its Dysfunction in Neurodegenerative Diseases
Shen, C.-K. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Neuronal Function of the Rna-Binding Protein Tdp-43 and Its Dysfunction in Neurodegenerative Diseases
Shen, C.-K. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Basic and Translational Research of the Active Dna De-Methylation Process by Mammalian Dna Methyltransferases- Physiological Functions and Regulatory Mechanisms
Shen, C.-K. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Hypoxia-induced genome-wide DNA demethylation by DNMT3A and EMT of cancer cells
Chatterjee, B., Majumder, P., Chen, C. C., Wang, J. P., Su, P. H., Lai, H. C., Liu, C. C., Lin, H. N., Yu, C. H. A., Yuan, H. S. & Shen, C. K. J., Dec 2025, In: Cellular and Molecular Biology Letters. 30, 1, 95.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Cabozantinib promotes erythroid differentiation in K562 erythroleukemia cells through global changes in gene expression and JNK activation
Fu, Y. H., Ou, D. L., Yang, Y. R., Su, K. W., Chen, C. Y., Tien, H. F., Lai, Z. S., Shen, C. K. J., Chien, H. F. & Lin, L. I., Jun 2022, In: Cancer Gene Therapy. 29, 6, p. 784-792 9 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Genetic Disruption of KLF1 K74 SUMOylation in Hematopoietic System Promotes Healthy Longevity in Mice
Shyu, Y. C., Liao, P. C., Huang, T. S., Yang, C. J., Lu, M. J., Huang, S. M., Lin, X. Y., Liou, C. C., Kao, Y. H., Lu, C. H., Peng, H. L., Chen, J. R., Cherng, W. J., Yang, N. I., Chen, Y. C., Pan, H. C., Jiang, S. T., Hsu, C. C., Lin, G. & Yuan, S. S. & 4 others, , Sept 5 2022, In: Advanced Science. 9, 25, 2201409.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Activation of a hippocampal CREB-pCREB-miRNA-MEF2 axis modulates individual variation of spatial learning and memory capability
Wang, I. F., Wang, Y., Yang, Y. H., Huang, G. J., Tsai, K. J. & Shen, C. K. J., Aug 2021, In: Cell Reports. 36, 5, 109477.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
A positive regulatory feedback loop between eklf/klf1 and tal1/scl sustaining the erythropoiesis
Hung, C. H., Lee, T. L., Huang, A. Y. S., Yang, K. C., Shyu, Y. C., Wen, H. C., Lu, M. J., Yuan, S. & Shen, C. K. J., Aug 2021, In: International journal of molecular sciences. 22, 15, 8024.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus)
Datasets
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Additional file 1: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, K.-H. (Creator), Lin, J.-H. (Contributor), Huang, C.-C. (Contributor), Chang, W.-C. (Creator), Shen, C.-K. J. (Contributor), Kao, T.-J. (Contributor), Lee, Y.-C. (Creator), Lin, H.-C. (Contributor), Huang, W.-C. (Contributor) & Lin, H.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313777.v1, https://doi.org/10.6084%2Fm9.figshare.7313777.v1
Dataset
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Additional file 2: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, Y.-C. (Creator), Lee, K.-H. (Creator), Shen, C.-K. J. (Contributor), Chang, W.-C. (Creator), Lin, J.-H. (Contributor), Huang, W.-C. (Contributor), Lin, H.-C. (Contributor), Lin, H.-C. (Contributor), Kao, T.-J. (Contributor) & Huang, C.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313798.v1, https://doi.org/10.6084%2Fm9.figshare.7313798.v1
Dataset
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MOESM9 of A robust TDP-43 knock-in mouse model of ALS
Wu, L.-S. (Contributor), Fang, Y.-S. (Creator), Chen, Y.-R. (Contributor), Cheng, W.-C. (Creator), Chang, C.-W. (Contributor), Lee, M. (Creator), Cheng, P.-L. (Creator), Shen, C.-K. J. (Contributor) & Huang, S.-L. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686545.v1, https://doi.org/10.6084%2Fm9.figshare.11686545.v1
Dataset
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MOESM6 of A robust TDP-43 knock-in mouse model of ALS
Wu, L.-S. (Contributor), Cheng, P.-L. (Creator), Chang, C.-W. (Contributor), Shen, C.-K. J. (Contributor), Huang, S.-L. (Contributor), Fang, Y.-S. (Creator), Lee, M. (Creator), Cheng, W.-C. (Creator) & Chen, Y.-R. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686530.v1, https://doi.org/10.6084%2Fm9.figshare.11686530.v1
Dataset
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MOESM10 of A robust TDP-43 knock-in mouse model of ALS
Wu, L.-S. (Contributor), Lee, M. (Creator), Shen, C.-K. J. (Contributor), Cheng, P.-L. (Creator), Cheng, W.-C. (Creator), Fang, Y.-S. (Creator), Huang, S.-L. (Contributor), Chang, C.-W. (Contributor) & Chen, Y.-R. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686482.v1, https://doi.org/10.6084%2Fm9.figshare.11686482.v1
Dataset