Projects per year
Personal profile
Education
Experience
- 2019.08- Chair Professor, Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
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Dive into the research topics where Che-Kun Shen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 9 Finished
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一個重要RNA結合蛋白標的TDP-43的神經功能及它在神經退化疾病上的角色(2/3)
Shen, C.-K. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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哺乳類動物DNA甲基化酶的新功能─去DNA甲基化活性的生理角色, 調控機制, 與轉譯研究(3/3)
Shen, C.-K. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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112年度【治療重症地中海貧血與鐮刀型貧血候選藥物AS-28之臨床前試驗(I)】
Shen, C.-K. (PI)
7/1/23 → 12/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Neuronal Function of the Rna-Binding Protein Tdp-43 and Its Dysfunction in Neurodegenerative Diseases (1/3)
Shen, C.-K. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Basic and Translational Research of the Active Dna De-Methylation Process by Mammalian Dna Methyltransferases- Physiological Functions and Regulatory Mechanisms
Shen, C.-K. (PI)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Cabozantinib promotes erythroid differentiation in K562 erythroleukemia cells through global changes in gene expression and JNK activation
Fu, Y. H., Ou, D. L., Yang, Y. R., Su, K. W., Chen, C. Y., Tien, H. F., Lai, Z. S., Shen, C. K. J., Chien, H. F. & Lin, L. I., Jun 2022, In: Cancer Gene Therapy. 29, 6, p. 784-792 9 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Genetic Disruption of KLF1 K74 SUMOylation in Hematopoietic System Promotes Healthy Longevity in Mice
Shyu, Y. C., Liao, P. C., Huang, T. S., Yang, C. J., Lu, M. J., Huang, S. M., Lin, X. Y., Liou, C. C., Kao, Y. H., Lu, C. H., Peng, H. L., Chen, J. R., Cherng, W. J., Yang, N. I., Chen, Y. C., Pan, H. C., Jiang, S. T., Hsu, C. C., Lin, G. & Yuan, S. S. & 4 others, , Sept 5 2022, In: Advanced Science. 9, 25, 2201409.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
Activation of a hippocampal CREB-pCREB-miRNA-MEF2 axis modulates individual variation of spatial learning and memory capability
Wang, I. F., Wang, Y., Yang, Y. H., Huang, G. J., Tsai, K. J. & Shen, C. K. J., Aug 2021, In: Cell Reports. 36, 5, 109477.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
A positive regulatory feedback loop between eklf/klf1 and tal1/scl sustaining the erythropoiesis
Hung, C. H., Lee, T. L., Huang, A. Y. S., Yang, K. C., Shyu, Y. C., Wen, H. C., Lu, M. J., Yuan, S. & Shen, C. K. J., Aug 2021, In: International journal of molecular sciences. 22, 15, 8024.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease
Lai, Z. S., Yeh, T. K., Chou, Y. C., Hsu, T., Lu, C. T., Kung, F. C., Hsieh, M. Y., Lin, C. H., Chen, C. T., Shen, C.-K. & Jiaang, W. T., Jan 2021, In: European Journal of Medicinal Chemistry. 209, 112938.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)
Datasets
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MOESM2 of A robust TDP-43 knock-in mouse model of ALS
Chang, C.-W. (Contributor), Huang, S.-L. (Contributor), Lee, M. (Creator), Cheng, W.-C. (Creator), Chen, Y.-R. (Contributor), Wu, L.-S. (Contributor), Fang, Y.-S. (Creator), Cheng, P.-L. (Creator) & Shen, C.-K. J. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686503.v1, https://doi.org/10.6084%2Fm9.figshare.11686503.v1
Dataset
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MOESM9 of A robust TDP-43 knock-in mouse model of ALS
Wu, L.-S. (Contributor), Fang, Y.-S. (Creator), Chen, Y.-R. (Contributor), Cheng, W.-C. (Creator), Chang, C.-W. (Contributor), Lee, M. (Creator), Cheng, P.-L. (Creator), Shen, C.-K. J. (Contributor) & Huang, S.-L. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686545.v1, https://doi.org/10.6084%2Fm9.figshare.11686545.v1
Dataset
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MOESM3 of A robust TDP-43 knock-in mouse model of ALS
Wu, L.-S. (Contributor), Cheng, W.-C. (Creator), Huang, S.-L. (Contributor), Fang, Y.-S. (Creator), Lee, M. (Creator), Chang, C.-W. (Contributor), Cheng, P.-L. (Creator), Chen, Y.-R. (Contributor) & Shen, C.-K. J. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686512.v1, https://doi.org/10.6084%2Fm9.figshare.11686512.v1
Dataset
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Additional file 1: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology
Lee, K.-H. (Creator), Lin, J.-H. (Contributor), Huang, C.-C. (Contributor), Chang, W.-C. (Creator), Shen, C.-K. J. (Contributor), Kao, T.-J. (Contributor), Lee, Y.-C. (Creator), Lin, H.-C. (Contributor), Huang, W.-C. (Contributor) & Lin, H.-C. (Contributor), Figshare, 2018
DOI: 10.6084/m9.figshare.7313777.v1, https://doi.org/10.6084%2Fm9.figshare.7313777.v1
Dataset
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MOESM1 of A robust TDP-43 knock-in mouse model of ALS
Cheng, W.-C. (Creator), Cheng, P.-L. (Creator), Chen, Y.-R. (Contributor), Huang, S.-L. (Contributor), Fang, Y.-S. (Creator), Chang, C.-W. (Contributor), Lee, M. (Creator), Shen, C.-K. J. (Contributor) & Wu, L.-S. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686497.v1, https://doi.org/10.6084%2Fm9.figshare.11686497.v1
Dataset