Projects per year
Personal profile
Education
Experience
- 2019.08- Chair Professor, Ph.D. Program for Neural Regenerative Medicine, Taipei Medical University
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Dive into the research topics where Che-Kun Shen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Neuronal Function of the Rna-Binding Protein Tdp-43 and Its Dysfunction in Neurodegenerative Diseases (1/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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Basic and Translational Research of the Active Dna De-Methylation Process by Mammalian Dna Methyltransferases- Physiological Functions and Regulatory Mechanisms
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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Basic and Translational Study of the Neuronal Functions of Tdp-43 Protein and Its Dysfunction in Neurodegenerative Diseases( III )
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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哺乳類動物DNA甲基化?的新功能─去DNA甲基化活性的生理角色, 調控機制, 與轉譯研究(1/3)
8/1/21 → 7/31/22
Project: A - Government Institution › b - Ministry of Science and Technology
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TDP-43蛋白在神經細胞中功能及在神經退化疾病上角色的基礎與轉譯研究(2/3)
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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Cabozantinib promotes erythroid differentiation in K562 erythroleukemia cells through global changes in gene expression and JNK activation
Fu, Y. H., Ou, D. L., Yang, Y. R., Su, K. W., Chen, C. Y., Tien, H. F., Lai, Z. S., Shen, C. K. J., Chien, H. F. & Lin, L. I., Jun 2022, In: Cancer Gene Therapy. 29, 6, p. 784-792 9 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Genetic Disruption of KLF1 K74 SUMOylation in Hematopoietic System Promotes Healthy Longevity in Mice
Shyu, Y. C., Liao, P. C., Huang, T. S., Yang, C. J., Lu, M. J., Huang, S. M., Lin, X. Y., Liou, C. C., Kao, Y. H., Lu, C. H., Peng, H. L., Chen, J. R., Cherng, W. J., Yang, N. I., Chen, Y. C., Pan, H. C., Jiang, S. T., Hsu, C. C., Lin, G., Yuan, S. S., & 4 others, Sept 5 2022, In: Advanced Science. 9, 25, 2201409.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of a hippocampal CREB-pCREB-miRNA-MEF2 axis modulates individual variation of spatial learning and memory capability
Wang, I. F., Wang, Y., Yang, Y. H., Huang, G. J., Tsai, K. J. & Shen, C. K. J., Aug 2021, In: Cell Reports. 36, 5, 109477.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
A positive regulatory feedback loop between eklf/klf1 and tal1/scl sustaining the erythropoiesis
Hung, C. H., Lee, T. L., Huang, A. Y. S., Yang, K. C., Shyu, Y. C., Wen, H. C., Lu, M. J., Yuan, S. & Shen, C. K. J., Aug 2021, In: International journal of molecular sciences. 22, 15, 8024.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease
Lai, Z. S., Yeh, T. K., Chou, Y. C., Hsu, T., Lu, C. T., Kung, F. C., Hsieh, M. Y., Lin, C. H., Chen, C. T., Shen, C-K. & Jiaang, W. T., Jan 2021, In: European Journal of Medicinal Chemistry. 209, 112938.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)
Datasets
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MOESM2 of A robust TDP-43 knock-in mouse model of ALS
Chang, C. (Contributor), Huang, S. (Contributor), Lee, M. (Creator), Cheng, W. (Creator), Chen, Y. (Contributor), Wu, L. (Contributor), Fang, Y. (Creator), Cheng, P. (Creator) & Shen, C. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686503.v1, https://doi.org/10.6084%2Fm9.figshare.11686503.v1
Dataset
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MOESM3 of A robust TDP-43 knock-in mouse model of ALS
Wu, L. (Contributor), Cheng, W. (Creator), Huang, S. (Contributor), Fang, Y. (Creator), Lee, M. (Creator), Chang, C. (Contributor), Cheng, P. (Creator), Chen, Y. (Contributor) & Shen, C. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11686512.v1, https://doi.org/10.6084%2Fm9.figshare.11686512.v1
Dataset
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MOESM5 of A robust TDP-43 knock-in mouse model of ALS
Chang, C. (Contributor), Chen, Y. (Contributor), Wu, L. (Contributor), Huang, S. (Contributor), Fang, Y. (Creator), Cheng, P. (Creator), Shen, C. (Contributor), Cheng, W. (Creator) & Lee, M. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.11686527.v1, https://doi.org/10.6084%2Fm9.figshare.11686527.v1
Dataset
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A robust TDP-43 knock-in mouse model of ALS
Wu, L. (Contributor), Huang, S. (Contributor), Cheng, W. (Creator), Cheng, P. (Creator), Chang, C. (Contributor), Fang, Y. (Creator), Chen, Y. (Contributor), Shen, C. (Contributor) & Lee, M. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.4825935.v1, https://doi.org/10.6084%2Fm9.figshare.c.4825935.v1
Dataset
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MOESM11 of A robust TDP-43 knock-in mouse model of ALS
Shen, C. (Contributor), Lee, M. (Creator), Chang, C. (Contributor), Chen, Y. (Contributor), Wu, L. (Contributor), Fang, Y. (Creator), Cheng, W. (Creator), Huang, S. (Contributor) & Cheng, P. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.11686491.v1, https://doi.org/10.6084%2Fm9.figshare.11686491.v1
Dataset