Projects per year
Personal profile
Education
- 2005 The National Defense University Ph.D., The Graduate Institute of Life Sciences(GILS) , Taiwan
- 1997 M.S. Biology, Fu Jen Catholic University, Taiwan
- 1995 B.S. Biology, Fu Jen Catholic University, Taiwan
Experience
- 2024- Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University, Taiwan
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2020- Associate Professor, International Ph.D. Program for Translational Science, Taipei Medical University, Taiwan
- 2020- Jointly Appointed Associate Professor, Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, Taipei Medical University, Taiwan
- 2018- Jointly Appointed Associate Professor, Ph.D. Program in Biotechnology Research and Development, College of Pharmacy, Taipei Medical University
- 2018- Jointly Appointed Associate Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2018-2024 Associate Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University, Taiwan
- 2017-2018 Jointly Appointed Assistant Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2012-2018 Assistant Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University, Taiwan
- 2005-2012 Postdoc fellow, Institute of Biomedical Sciences, Academia Sinica, Taiwan
Research Interests
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Post-translational modification
- Signal transduction in cancer
- Gene transcriptional regulation
- Molecular cell biology
Related Link
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Novel Therapeutic Strategy for Cns Atrt: Identifying Potential Targets for Reduced-Dose Radiotherapy and Their Applications in Preclinical Studies
Chang, C.-C. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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The Discovery of Potential Therapeutic Targets and Its Application in Cns At/Rt Preclinical Studies( I )
Chang, C.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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The discovery of a EZH2 inhibitor as a potential cancer treatment for MB and ATRT
Chang, C.-C. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(2/3)
Chang, C.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(2/3)
Chang, C.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Delivery of LOXL1-AS1-siRNAs using targeting peptide-engineered extracellular vesicles with focused ultrasound to suppress medulloblastoma metastasis
Do, A. D., Chu, S. S., Giang, L. H., Huang, P. L., Lin, Y. L., Chang, C. C., Wong, T. T., Sung, S. Y. & Hsieh, C. L., Dec 2025, In: Journal of Nanobiotechnology. 23, 1, 460.Research output: Contribution to journal › Article › peer-review
Open Access -
Explainable machine learning model for identifying key gut microbes and metabolites biomarkers associated with myasthenia gravis
Chang, C. C., Liu, T. C., Lu, C. J., Chiu, H. C. & Lin, W. N., Dec 2024, In: Computational and Structural Biotechnology Journal. 23, p. 1572-1583 12 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
LOXL1-AS1 contributes to metastasis in sonic-hedgehog medulloblastoma by promoting cancer stem-like phenotypes
Do, A. D., Wu, K. S., Chu, S. S., Giang, L. H., Lin, Y. L., Chang, C. C., Wong, T. T., Hsieh, C. L. & Sung, S. Y., Dec 2024, In: Journal of Experimental and Clinical Cancer Research. 43, 1, 130.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
RRM2 inhibition alters cell cycle through ATM/Rb/E2F1 pathway in atypical teratoid rhabdoid tumor
Giang, L. H., Wu, K. S., Lee, W. C., Chu, S. S., Do, A. D., Huang, M. H., Lin, Y. L., Hsieh, C. L., Sung, S. Y., Yen, Y., Wong, T. T. & Chang, C. C., Dec 2024, In: Neoplasia (United States). 58, 101075.Research output: Contribution to journal › Article › peer-review
Open Access -
SENP2 restrains the generation of pathogenic Th17 cells in mouse models of colitis
Yang, T. T., Chiang, M. F., Chang, C. C., Yang, S. Y., Huang, S. W., Liao, N. S., Shih, H. M., Hsu, W. & Lin, K. I., Dec 2023, In: Communications Biology. 6, 1, 629.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus)
Datasets
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Additional file 8: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552550.v1, https://springernature.figshare.com/articles/Additional_file_8_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552550/1
Dataset
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Additional file 2: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552514.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552514/1
Dataset
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Additional file 10: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552460.v1, https://springernature.figshare.com/articles/Additional_file_10_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552460/1
Dataset
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Additional file 7: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552544.v1, https://springernature.figshare.com/articles/Additional_file_7_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552544/1
Dataset
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Additional file 4: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552526.v1, https://springernature.figshare.com/articles/Additional_file_4_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552526/1
Dataset