Projects per year
Personal profile
Education
- 2005 The National Defense University Ph.D., The Graduate Institute of Life Sciences(GILS) , Taiwan
- 1997 M.S. Biology, Fu Jen Catholic University, Taiwan
- 1995 B.S. Biology, Fu Jen Catholic University, Taiwan
Experience
- 2024- Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University, Taiwan
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2020- Associate Professor, International Ph.D. Program for Translational Science, Taipei Medical University, Taiwan
- 2020- Jointly Appointed Associate Professor, Master Program in Clinical Pharmacogenomics and Pharmacoproteomics, Taipei Medical University, Taiwan
- 2018- Jointly Appointed Associate Professor, Ph.D. Program in Biotechnology Research and Development, College of Pharmacy, Taipei Medical University
- 2018- Jointly Appointed Associate Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2018-2024 Associate Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University, Taiwan
- 2017-2018 Jointly Appointed Assistant Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
- 2012-2018 Assistant Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University, Taiwan
- 2005-2012 Postdoc fellow, Institute of Biomedical Sciences, Academia Sinica, Taiwan
Research Interests
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Post-translational modification
- Signal transduction in cancer
- Gene transcriptional regulation
- Molecular cell biology
Related Link
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Dive into the research topics where Che-Chang Chang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(3/3)
Chang, C.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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The discovery of a EZH2 inhibitor as a potential cancer treatment for MB and ATRT
Chang, C.-C. (PI)
7/1/24 → 2/28/25
Project: A - Government Institution › b - National Science and Technology Council
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開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(2/3)
Chang, C.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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開發用於中樞非典型畸形/橫紋肌樣瘤治療的潛在標的並探討其在臨床前試驗的應用(2/3)
Chang, C.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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利用in vitro和in vivo平台檢測小泛素化蛋白抗體的專一性及其在臨床檢體之應用
Chang, C.-C. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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LOXL1-AS1 contributes to metastasis in sonic-hedgehog medulloblastoma by promoting cancer stem-like phenotypes
Do, A. D., Wu, K. S., Chu, S. S., Giang, L. H., Lin, Y. L., Chang, C. C., Wong, T. T., Hsieh, C. L. & Sung, S. Y., Dec 2024, In: Journal of Experimental and Clinical Cancer Research. 43, 1, 130.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
RRM2 inhibition alters cell cycle through ATM/Rb/E2F1 pathway in atypical teratoid rhabdoid tumor
Giang, L. H., Wu, K. S., Lee, W. C., Chu, S. S., Do, A. D., Huang, M. H., Lin, Y. L., Hsieh, C. L., Sung, S. Y., Yen, Y., Wong, T. T. & Chang, C. C., Dec 2024, In: Neoplasia (United States). 58, 101075.Research output: Contribution to journal › Article › peer-review
Open Access -
SENP2 restrains the generation of pathogenic Th17 cells in mouse models of colitis
Yang, T. T., Chiang, M. F., Chang, C. C., Yang, S. Y., Huang, S. W., Liao, N. S., Shih, H. M., Hsu, W. & Lin, K. I., Dec 2023, In: Communications Biology. 6, 1, 629.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor
Giang, L. H., Wu, K. S., Lee, W. C., Chu, S. S., Do, A. D., Changou, C. A., Tran, H. M., Hsieh, T. H., Chen, H. H., Hsieh, C. L., Sung, S. Y., Yu, A. L., Yen, Y., Wong, T. T. & Chang, C. C., Dec 2023, In: Journal of Experimental and Clinical Cancer Research. 42, 1, 346.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
A PIAS1 Protective Variant S510G Delays polyQ Disease Onset by Modifying Protein Homeostasis
Lee, Y. H., Tsai, Y. S., Chang, C. C., Ho, C. C., Shih, H. M., Chen, H. M., Lai, H. L., Lee, C. W., Lee, Y. C., Liao, Y. C., Yang, U. C., Cheng, T. H., Chern, Y. & Soong, B. W., Apr 2022, In: Movement Disorders. 37, 4, p. 767-777 11 p.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus)
Datasets
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Additional file 7: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552544.v1, https://springernature.figshare.com/articles/Additional_file_7_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552544/1
Dataset
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Additional file 14: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552487.v1, https://springernature.figshare.com/articles/Additional_file_14_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552487/1
Dataset
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Additional file 5: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552532.v1, https://springernature.figshare.com/articles/Additional_file_5_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552532/1
Dataset
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Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women
Tsai, K.-L. (Contributor), Lu, Y.-Y. (Creator), Lin, Y.-F. (Creator), Tsai, I.-J. (Contributor), Lin, C.-Y. (Creator), Lin, S.-H. (Creator), Chang, C.-C. (Creator), Chen, J.-H. (Creator), Tai, C.-C. (Contributor), Su, E.C.-Y. (Creator), Chang, Y.-S. (Creator) & Chang, H.-W. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5301174.v1, https://doi.org/10.6084%2Fm9.figshare.c.5301174.v1
Dataset
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Additional file 1 of Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women
Chen, J.-H. (Creator), Chang, Y.-S. (Creator), Lin, C.-Y. (Creator), Su, E.C.-Y. (Creator), Tsai, K.-L. (Contributor), Lin, S.-H. (Creator), Lu, Y.-Y. (Creator), Lin, Y.-F. (Creator), Chang, H.-W. (Creator), Tai, C.-C. (Contributor), Tsai, I.-J. (Contributor) & Chang, C.-C. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.13889385.v1, https://doi.org/10.6084%2Fm9.figshare.13889385.v1
Dataset