Bing-Chang Chen

Projects

Projects per year 2010 2012 2013 2014 2015 2018 2019 2020 2022 2023 2025

• 1 Active
• 43 Finished

Projects per year

Search results

• Active

  Investigation of the Pathological Function of Lemur Tyrosine Kinase 3 (Lmtk3) in Thrombin-Induced Il-8/Cxcl8 Expression and Airway Inflammation in Type-2-Low Severe Asthma

  Chen, B.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council
• Finished

  Doublecortin like kinase protein 1 (DCLK1)在支氣管肺纖維化中的病理生理學研究－ADAM17/ACE2調控DCLK1過度的表現參與呼吸道纖維化角色探討(2/3)

  Chen, B.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討serine/threonine kinase 33 (STK33)於嚴重氣喘中thrombin誘導趨化因子IL-8/CXCL8表現及氣道發炎之病理角色

  Chen, B.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討Pref-1在人類肺部纖維母細胞中誘導DCLK1表現的機制

  Chen, B.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討DCLK1/IL-23在漸進纖維化間質性肺病之病理角色

  Chen, B.-C. (PI)

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Study on the Pathological Role of Dclk1 in Thrombin-Induced Il-8/Cxcl8 Expression and Airway Inflammation in Chronic Obstructive Asthma

  Chen, B.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Study on the Role of Adam17/Ace2 in Doublecortin Like Kinase 1 (Dclk1) Overexpression Responsible for Airway Fibrosis( I )

  Chen, B.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• ADAM17/CX3CL1在TGF-ꞵ誘導的促纖維化蛋白及纖維母細胞的分化在嚴重氣喘病人的氣道纖維化

  Chen, B.-C. (PI)

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Study on the Pathological Role of Dclk1 in Thrombin-Induced Il-8/Cxcl8 Expression and Airway Inflammation in Chronic Obstructive Asthma

  Chen, B.-C. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 雙皮質素樣激酶1在IL-13誘導的TSLP表現和第二型發炎誘發之氣管纖維化的研究

  Chen, B.-C. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Study on the Pathological Role of Dclk1 in Thrombin-Induced Il-8/Cxcl8 Expression and Airway Inflammation in Chronic Obstructive Asthma

  Chen, B.-C. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of Role of Adam17/Preadipocyte Factor-1 in Hypoxia-Induced Ctgf Expression and Airway Fibrosis( III )

  Chen, B.-C. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• ERK/p65及p300在Pref-1誘導肺部纖維母細胞CTGF表現之研究

  Chen, B.-C. (PI)

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 雙皮質素樣激酶1在IL-13誘導的TSLP表現和第二型發炎誘發之氣管纖維化的研究

  Chen, B.-C. (PI)

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Investigation of Role of Adam17/Preadipocyte Factor-1 in Hypoxia-Induced Ctgf Expression and Airway Fibrosis( II )

  Chen, B.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Studies on the Role of Stomatin-Like Protein 2 (Stoml2) in Thrombin-Stimulated Il-8/Cxcl8 Expression and Airway Inflammation(3/3)

  Chen, B.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Amphiregulin促進TGF-β刺激肺部上皮細胞CCN2表現及上皮-間質細胞轉換之研究

  Chen, B.-C. (PI)

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - National Science and Technology Council

• 雙皮質素樣激酶1 在氣管及胸膜纖維化中的作用-去整合素和金屬蛋白酶蛋白質17/雙皮質素樣激酶1 在TGF-β 誘導的CTGF 表現和氣管纖維化中的研究

  Chen, B.-C. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Investigation of Role of Adam17/Preadipocyte Factor-1 in Hypoxia-Induced Ctgf Expression and Airway Fibrosis(1/3)

  Chen, B.-C. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• Studies on the Role of Stomatin-Like Protein 2 (Stoml2) in Thrombin-Stimulated Il-8/Cxcl8 Expression and Airway Inflammation(2/3)

  Chen, B.-C. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• 研究ADAM10/Notch1調控TGF-β誘導肺部上皮細胞CTGF表現之分子機轉探討

  Chen, B.-C. (PI)

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - National Science and Technology Council

• 雙皮質素樣激酶1 在氣管及胸膜纖維化中的作用

  Chen, B.-C. (PI)

  1/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Studies on the Role of Stomatin-Like Protein 2 (Stoml2) in Thrombin-Stimulated Il-8/Cxcl8 Expression and Airway Inflammation

  Chen, B.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.-C. (PI)

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Thrombin 100%
  • Orosomucoid 100%
  • Respiratory Tract Inflammation 100%
  • Interleukin 8 100%
  • Small Interfering RNA 28%

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (III)

  Chen, B.-C. (PI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Tumor Necrosis Factor Alpha Converting Enzyme 100%
  • Lung Fibrosis 100%
  • Connective Tissue Growth Factor 100%
  • Hypoxia 100%
  • ADAM17 100%

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.-C. (PI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Thrombin 100%
  • Respiratory Tract Inflammation 100%
  • Orosomucoid 100%
  • Interleukin 8 100%
  • Small Interfering RNA 28%

• EGFR反式活化依賴NADPH oxidase/ROS/NF-kB路徑媒介thrombin誘導肺部上皮細胞IL-8/CXCL8表現之探討

  Chen, B.-C. (PI)

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• TGF-beta誘導人類肺癌細胞JARID2表現之機轉研究

  Chen, B.-C. (PI)

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.-C. (PI)

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - National Science and Technology Council

  • Thrombin 100%
  • Respiratory Tract Inflammation 100%
  • Orosomucoid 100%
  • Interleukin 8 100%
  • Small Interfering RNA 28%

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (II)

  Chen, B.-C. (PI)

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - National Science and Technology Council

• TGF-beta誘導人類大腸癌細胞CTGF表現之機轉研究

  Chen, B.-C. (PI)

  6/1/14 → 8/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• Casein kinas 2/MSK1依賴NF-kB活化媒介thrombin誘導肺部上皮細胞IL-8/CXCL8表現之探討

  Chen, B.-C. (PI)

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (I)

  Chen, B.-C. (PI)

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - National Science and Technology Council

• Studies on the signal pathways of CAAT/enhancer binding protein beta mediate thrombin-induced IL-8/CXCL8 expression in human lung epithelial cells

  Chen, B.-C. (PI)

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - National Science and Technology Council

• MEKK1/JNK依賴SMAD3活化媒介CXCL12誘導肺部纖維母細胞CTGF表現之探討

  Chen, B.-C. (PI)

  6/1/13 → 5/31/14

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Ghrelin誘導人類大腸癌細胞增生與轉移機轉研究

  Chen, B.-C. (PI)

  5/1/13 → 5/31/14

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B.-C. (PI)

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - National Science and Technology Council

  • Pulmonary Fibrosis 100%
  • Hypoxia 100%
  • Lung Fibrosis 100%
  • Fibroblast 100%
  • Lung Fibroblast 60%

• Studies on the Signal Pathways of Caat/Enhancer Binding Protein Beta Mediate Thrombin-Induced Il-8/Cxcl8 Expression in Human Lung Epithelial Cells

  Chen, B.-C. (PI)

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - National Science and Technology Council

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B.-C. (PI) & Chung, C.-L. (CoI)

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Pulmonary Fibrosis 100%
  • Hypoxia 100%
  • Lung Fibrosis 100%
  • Fibroblast 100%
  • Lung Fibroblast 60%

• c-Src/NADPH oxidase/ROS訊息路徑參與表皮生長因子誘導人類大腸癌細胞heme oxygenase-1表現之研究

  Chen, B.-C. (PI)

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• CXCL12刺激人類肺部纖維母細胞結締組織生長因子表現之分子機制探討

  Chen, B.-C. (PI)

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Studies on the Signal Pathways of Caat/Enhancer Binding Protein Beta Mediate Thrombin-Induced Il-8/Cxcl8 Expression in Human Lung Epithelial Cells

  Chen, B.-C. (PI)

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - National Science and Technology Council

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B.-C. (PI) & Chung, C.-L. (CoI)

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - National Science and Technology Council

  • Pulmonary Fibrosis 100%
  • Hypoxia 100%
  • Lung Fibrosis 100%
  • Fibroblast 100%
  • Lung Fibroblast 60%

• Investigation of Chromatin Remodeling and Akt-Dependnet mTOR/S6K Mediate Thrombin-Induced IL-8/CXCL8 in Lung Epithelial Cells

  Chen, B.-C. (PI)

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - National Science and Technology Council

  • Interleukin 8 100%
  • Mammalian Target of Rapamycin 100%
  • Chromatin Remodeling 100%
  • Thrombin 100%
  • Chromatin Assembly and Disassembly 100%