Projects per year
Personal profile
Education
- 1994-1999 Ph.D., Institute of Pharmacology, College of Medicine, National Taiwan University
- 1985-1991 Department of Pharmacy, Chia Nan University of Pharmacy ＆ Science
Experience
- 2018.08- Vice Director, Research Center of Thoracic Medicine, Collagen of Medicine, Taipei Medical University
- 2018.01- Director, School of Respiratory Therapy, College of Medicine, Taipei Medical University
- 2016.08- Professor, Department of Internal Medicine, Collagen of Medicine, Taipei Medical University
- 2016.08-2017.07 Director, School of Respiratory Therapy, School of Medicine, Taipei Medical University
- 2010.02- Professor, School of Respiratory Therapy, Collagen of Medicine, Taipei Medical University
- 2006.02-2010.01 Associate Professor, School of Respiratory Therapy, Collagen of Medicine, Taipei Medical University
- 2002.06- 2006.01 Assistant Professor, School of Respiratory Therapy, Collagen of Medicine, Taipei Medical University
- 2001.08-2002.06 Postdoctoral Researcher, Tao-Yuan General Hospital, Ministry of Health and Welfare
- 2000.08-2002.07 Adjunct Assistant Professor, National Taiwan University of Science and Technology
- 1999.08-2001.07 Post doctor training, Institute of Pharmacology, College of Medicine, National Taiwan University
Awards
- 2010 Excellent Research Award from The Pharmacological Society in Taiwan
- 2003 Ta-You Wu Memorial Award from the National Science Council, ROC.
- 2000 Outstanding Paper Award from the The Pharmacological Society in Taiwan
- 2000 Outstanding Paper Award from the College of Medicine, National Taiwan University
Research Interests
- Pharmacology in respiratory diseases
- Molecular biology
- Signal transduction
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Collaborations and top research areas from the last five years
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Investigation of the Pathological Function of Lemur Tyrosine Kinase 3 (Lmtk3) in Thrombin-Induced Il-8/Cxcl8 Expression and Airway Inflammation in Type-2-Low Severe Asthma
Chen, B.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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探討serine/threonine kinase 33 (STK33)於嚴重氣喘中thrombin誘導趨化因子IL-8/CXCL8表現及氣道發炎之病理角色
Chen, B.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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Doublecortin like kinase protein 1 (DCLK1)在支氣管肺纖維化中的病理生理學研究－ADAM17/ACE2調控DCLK1過度的表現參與呼吸道纖維化角色探討(2/3)
Chen, B.-C. (PI)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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探討Pref-1在人類肺部纖維母細胞中誘導DCLK1表現的機制
Chen, B.-C. (PI)
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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探討DCLK1/IL-23在漸進纖維化間質性肺病之病理角色
Chen, B.-C. (PI)
1/1/23 → 12/31/23
Project: B - Project of TMU › h - Higher Education Sprout Project
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Desmethylclomipramine triggers mitochondrial damage and death in TGF-β-induced mesenchymal type of A549 cells
Shih, F. C., Lin, C. F., Wu, Y. C., Hsu, C. C., Chen, B. C., Chang, Y. C., Lin, Y. S., Satria, R. D., Lin, P. Y. & Chen, C. L., Aug 15 2024, In: Life Sciences. 351, 122817.Research output: Contribution to journal › Article › peer-review
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MPT0E028, a novel pan-HDAC inhibitor, prevents pulmonary fibrosis through inhibition of TGF-β-induced CTGF expression in human lung fibroblasts: Involvement of MKP-1 activation
Liu, C. H., Lee, H. S., Liou, J. P., Hua, H. S., Cheng, W. H., Yuliani, F. S., Chen, B. C. & Lin, C. H., Aug 15 2024, In: European Journal of Pharmacology. 977, 176711.Research output: Contribution to journal › Article › peer-review
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Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis
Cheng, W. H., Chang, P. L., Wu, Y. C., Wang, S. A., Chen, C. L., Hsu, F. L., Neoh, M. M., Lin, L. Y., Yuliani, F. S., Lin, C. H. & Chen, B. C., 2024, (Accepted/In press) In: Lung. 202, 3, p. 343-356 14 p.Research output: Contribution to journal › Article › peer-review
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Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by disrupting HDAC2/Sin3A/MeCP2 corepressor complex
Hua, H. S., Wen, H. C., Lee, H. S., Weng, C. M., Yuliani, F. S., Kuo, H. P., Chen, B. C. & Lin, C. H., Dec 2023, In: Journal of Biomedical Science. 30, 1, 40.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Amphiregulin induces CCN2 and fibronectin expression by TGF-β through EGFR-dependent pathway in lung epithelial cells
Cheng, W. H., Kao, S. Y., Chen, C.-L., Yuliani, F. S., Lin, L. Y., Lin, C. H. & Chen, B.-C., Dec 2022, In: Respiratory Research. 23, 1, 381.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus)