Projects per year
Personal profile
Education
- 2005 Ph.D. (Anatomy and Cell Biology), Queen's University, Kingston, Ontario, Canada
- 1997 B.S.(Biochemistry), Queen's University, Kingston, Ontario, Canada
Experience
- 2019- Associate Professor, Graduate Institute of Biomedical Informatics, Taipei Medical University
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2013- Associate Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University
- 2012-2013 Assistant Professor, The Ph.D. Program for Translational Medicine, Taipei Medical University
- 2008-2012 Assoistant Professor, Department of Radiology, Taipei Medical University
- 2010 Visiting scholar to Dr. Andrew Kung’s lab at Dana Farber Cancer Institute
Research Interests
- Cancer/stem cell biology
- Translational research
- New drug/therapeutic strategy development
- Regenerative medicine
- Biology and applications of extracellular vesicle
Related Link
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Dive into the research topics where Alexander TH Wu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Translational Investigation of Generating Enhanced Mscs and Secretome Using Mfp-Based Proprietary Culture Methods for Dcli Treatment( I )
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of a Sesquiterpene Lactone, Antrocin, as a Therapeutic Lead Compound and Its Nano-Enabled Form for Targeting Proneural-To-Mesenchymal Transition in Glioma Stem Cells
8/1/22 → 7/31/23
Project: A - Government Institution › b - Ministry of Science and Technology
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探討透過多功能胜肽培養後間葉幹細胞及其外泌體在冠狀動脈缺血性損傷上治療之功效及機制
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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Preclinical efficacy evaluation and mechanistic exploration of CII-NTTS
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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研究CEACAM6參與結直腸癌發生中的機制以及抗CEACAM6抗體偶合的納米粒子對轉移性結直腸癌的靶向療法和臨床前評估
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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Alterações dos parâmetros bioquímicos séricos e fosforilação da tirosina em rim e fígado de ratos induzidos por estresse crônico
Translated title of the contribution :Alterations of serum biochemical parameters and tyrosine phosphorylation in kidney and liver of chronic stress-induced rats Research output: Contribution to journal › Article › peer-review
Open Access -
In silico study of novel niclosamide derivatives, SARS-CoV-2 nonstructural proteins catalytic residue-targeting small molecules drug candidates
Lawal, B., Tsai, S. K., Wu, A. T. H. & Huang, H. S., May 2023, In: Arabian Journal of Chemistry. 16, 5, 104654.Research output: Contribution to journal › Article › peer-review
Open Access -
Multiomics Study of a Novel Naturally Derived Small Molecule, NSC772864, as a Potential Inhibitor of Proto-Oncogenes Regulating Cell Cycle Progression in Colorectal Cancer
Mokgautsi, N., Kuo, Y. C., Chen, C. H., Huang, Y. J., Wu, A. T. H. & Huang, H. S., Jan 2023, In: Cells. 12, 2, 340.Research output: Contribution to journal › Article › peer-review
Open Access -
Ovatodiolide and antrocin synergistically inhibit the stemness and metastatic potential of hepatocellular carcinoma via impairing ribosome biogenesis and modulating ERK/Akt-mTOR signaling axis
Chen, M. Y., Hsu, C. H., Setiawan, S. A., Tzeng, D. T. W., Ma, H. P., Ong, J. R., Chu, Y. C., Hsieh, M. S., Wu, A. T. H., Tzeng, Y. M. & Yeh, C. T., Jan 2023, In: Phytomedicine. 108, 154478.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Preclinical Evaluation of a Novel Small Molecule LCC-21 to Suppress Colorectal Cancer Malignancy by Inhibiting Angiogenic and Metastatic Signatures
Mokgautsi, N., Kuo, Y. C., Huang, Y. J., Chen, C. H., Mukhopadhyay, D., Wu, A. T. H. & Huang, H. S., Jan 2023, In: Cells. 12, 2, 266.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Additional file 2: Figure S1. of Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
Huynh, T. (Contributor), Tzeng, Y. (Contributor), Yen, Y. (Creator), Yang, C. (Contributor), Wu, A. T. (Creator), Meng, T. (Contributor), Whang-Peng, J. (Creator), Wei, P. (Contributor), Hsiao, M. (Creator) & Huang, Y. (Contributor), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3704533_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3704533_d1.v1
Dataset
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Additional file 3: Figure S2. of Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
Hsiao, M. (Creator), Yeh, C. (Contributor), Wu, A. T. (Creator), Wang, L. S. (Creator), Bamodu, O. A. (Contributor), Lee, W. (Contributor), Chao, T. (Contributor) & Huang, W. (Contributor), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3621719_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3621719_d2.v1
Dataset
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Additional file 2: Figure S1. of Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
Yeh, C. (Contributor), Huang, W. (Contributor), Wu, A. T. (Creator), Bamodu, O. A. (Contributor), Lee, W. (Contributor), Wang, L. S. (Creator), Chao, T. (Contributor) & Hsiao, M. (Creator), Figshare, 2016
DOI: 10.6084/m9.figshare.c.3621719_d3.v1, https://doi.org/10.6084%2Fm9.figshare.c.3621719_d3.v1
Dataset
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Additional file 4 of Neoadjuvant metformin added to conventional chemotherapy synergizes anti-proliferative effects in ovarian cancer
Lee, M. (Contributor), Wu, A. T. (Creator), Yeung, S. J. (Contributor), Wen, K. (Creator), Chou, P. (Contributor), Huang, C. F. (Contributor), Lin, J. (Contributor) & Sung, P. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.12845531.v1, https://doi.org/10.6084%2Fm9.figshare.12845531.v1
Dataset
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Seed extract of Thai Mucuna pruriens reduced male reproductive damage in rats induced by chronic stress
Sawatpanich, T. (Creator), Lapyuneyong, N. (Creator), Arun, S. (Creator), Choowong-In, P. (Creator), Iamsaard, S. (Creator), Uabundit, N. (Creator), Wu, A. T. (Creator), Tangsrisakda, N. (Creator) & Chaisiwamongkol, K. (Creator), Taylor & Francis, 2022
DOI: 10.6084/m9.figshare.19199363.v1, https://tandf.figshare.com/articles/journal_contribution/Seed_extract_of_Thai_i_Mucuna_pruriens_i_reduced_male_reproductive_damage_in_rats_induced_by_chronic_stress/19199363/1
Dataset