TMU Research Center of Drug Discovery

Search results

• Additional file 1: of Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model

  Yeh, Y.-L. (Creator), Wang, Y.-J. (Contributor), Chiu, H.-W. (Creator), Ho, S.-Y. (Contributor), Wang, Y.-C. (Contributor), Lin, P. (Contributor) & Huang, W.-J. (Contributor), Figshare, 2016

  DOI: 10.6084/m9.figshare.c.3697276_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276_d1.v1

  Dataset

• Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

  Pan, S.-L. (Contributor), Hsu, K.-C. (Creator), Lin, T. E. (Creator), Lin, C.-F. (Creator), Huang, H.-L. (Contributor) & Huangfu, W.-C. (Contributor), Figshare, 2020

  DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1

  Dataset

• MOESM10 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Tsai, F.-J. (Contributor), Lu, H.-F. (Contributor), Lin, Y.-J. (Creator), Chen, C.-H. (Contributor), Wu, J.-Y. (Contributor), Wong, H.S.-C. (Creator), Chang, W.-C. (Contributor) & Liao, W.-L. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270412.v1, https://doi.org/10.6084%2Fm9.figshare.10270412.v1

  Dataset

• Additional file 2 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

  Huang, H.-L. (Contributor), HuangFu, W.-C. (Creator), Cheng, Y.-W. (Creator), Cheng, C.-C. (Creator), Chang, F.-L. (Creator), Sung, T.-Y. (Creator), Pan, S.-L. (Creator), Lee, Y.-C. (Contributor), Wei, P.-L. (Contributor) & Huang, C.-C. (Contributor), Figshare, 2021

  DOI: 10.6084/m9.figshare.14228281.v1, https://doi.org/10.6084%2Fm9.figshare.14228281.v1

  Dataset

• Additional file 1 of EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

  Cheng, Y.-W. (Creator), Cheng, C.-C. (Creator), HuangFu, W.-C. (Creator), Pan, S.-L. (Creator), Sung, T.-Y. (Creator), Chang, F.-L. (Creator), Huang, H.-L. (Contributor), Huang, C.-C. (Contributor), Wei, P.-L. (Contributor) & Lee, Y.-C. (Contributor), Figshare, 2021

  DOI: 10.6084/m9.figshare.14228278.v1, https://doi.org/10.6084%2Fm9.figshare.14228278.v1

  Dataset

• MOESM4 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Chen, C.-H. (Contributor), Lu, H.-F. (Contributor), Liao, W.-L. (Creator), Wong, H.S.-C. (Creator), Wu, J.-Y. (Contributor), Chang, W.-C. (Contributor), Lin, Y.-J. (Creator) & Tsai, F.-J. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270445.v1, https://doi.org/10.6084%2Fm9.figshare.10270445.v1

  Dataset

• Structure-guided design of anti-cancer ribonucleotide reductase inhibitors

  Misko, T. A. (Contributor), Liu, Y.-T. (Contributor), Harris, M. E. (Contributor), Oleinick, N. L. (Contributor), Pink, J. (Contributor), Lee, H.-Y. (Contributor) & Dealwis, C. G. (Contributor), Unknown Publisher, Jan 1 2019

  DOI: 10.6084/m9.figshare.7553114.v1, https://tandf.figshare.com/articles/Structure-guided_design_of_anti-cancer_ribonucleotide_reductase_inhibitors/7553114/1

  Dataset

• Additional file 1: of Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

  Tsai, I.-T. (Contributor), Kuo, C.-C. (Contributor), Liou, J.-P. (Contributor) & Chang, J.-Y. (Contributor), Unknown Publisher, Mar 28 2018

  DOI: 10.6084/m9.figshare.6061133.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Novel_microtubule_inhibitor_MPT0B098_inhibits_hypoxia-induced_epithelial-to-mesenchymal_transition_in_head_and_neck_squamous_cell_carcinoma/6061133/1

  Dataset

• Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model

  Chiu, H.-W. (Creator), Yeh, Y.-L. (Creator), Wang, Y.-C. (Contributor), Huang, W.-J. (Contributor), Ho, S.-Y. (Contributor), Lin, P. (Contributor) & Wang, Y.-J. (Contributor), Figshare, 2016

  DOI: 10.6084/m9.figshare.c.3697276.v1, https://doi.org/10.6084%2Fm9.figshare.c.3697276.v1

  Dataset

• Additional file 1: of CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation

  Chen, Y.-L. (Contributor), Chuang, J.-Y. (Creator), Wang, S.-M. (Creator), Kao, T.-J. (Contributor), Lin, H.-Y. (Creator), Ko, C.-Y. (Contributor) & Hsu, T.-I. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.8866895.v1, https://doi.org/10.6084%2Fm9.figshare.8866895.v1

  Dataset

• Additional file 2: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

  Chao, M.-W. (Contributor), Chang, L.-H. (Contributor), Tu, H.-J. (Contributor), Chang, C.-D. (Contributor), Lai, M.-J. (Contributor), Chen, Y.-Y. (Creator), Liou, J.-P. (Creator), Teng, C.-M. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.8202887.v1, https://springernature.figshare.com/articles/Additional_file_2_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202887/1

  Dataset

• Additional file 2 of Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation

  Li, C.-H. (Creator), Ho, J.-D. (Contributor), Chan, Y.-J. (Contributor), Chen, C.-Y. (Contributor), Cheng, Y.-W. (Creator), Lin, F.-L. (Contributor), Liao, P.-L. (Contributor) & Tsai, C.-H. (Contributor), Figshare, 2021

  DOI: 10.6084/m9.figshare.13550761.v1, https://doi.org/10.6084%2Fm9.figshare.13550761.v1

  Dataset

• MOESM1 of The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury

  Wang, Y.-J. (Contributor), Wong, H. (Contributor), Wu, C.-C. (Contributor), Chiang, Y.-H. (Contributor), Chiu, W.-T. (Contributor), Chen, K.-Y. (Contributor) & Chang, W.-C. (Contributor), Unknown Publisher, Jan 1 2019

  DOI: 10.6084/m9.figshare.11302148.v1, https://springernature.figshare.com/articles/MOESM1_of_The_functional_roles_of_IGF-1_variants_in_the_susceptibility_and_clinical_outcomes_of_mild_traumatic_brain_injury/11302148/1

  Dataset

• Additional file 4: of Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

  Chao, M.-W. (Contributor), Chang, L.-H. (Contributor), Tu, H.-J. (Contributor), Chang, C.-D. (Contributor), Lai, M.-J. (Contributor), Chen, Y.-Y. (Creator), Liou, J.-P. (Creator), Teng, C.-M. (Contributor) & Pan, S.-L. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.8202896.v1, https://springernature.figshare.com/articles/Additional_file_4_of_Combination_treatment_strategy_for_pancreatic_cancer_involving_the_novel_HDAC_inhibitor_MPT0E028_with_a_MEK_inhibitor_beyond_K-Ras_status/8202896/1

  Dataset

• Additional file 1 of Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer

  Liu, E.-S. (Contributor), Wang, C.-K. (Contributor), Chuang, K.-H. (Contributor), Chen, F.-M. (Creator), Wu, T.-H. (Contributor), Chen, C.-Y. (Creator), Chen, I.-J. (Creator), Lin, R.-A. (Creator), Wang, Y.-M. (Contributor), Lu, Y.-C. (Contributor), Liao, T.-Y. (Contributor), Chen, H.-J. (Creator), Cheng, T.-L. (Creator) & Cheng, Y.-A. (Creator), Figshare, 2020

  DOI: 10.6084/m9.figshare.12885938.v1, https://doi.org/10.6084%2Fm9.figshare.12885938.v1

  Dataset

• The association between BDNF Val66Met polymorphism and emotional symptoms after mild traumatic brain injury

  Wang, Y.-J. (Creator), Chen, K.-Y. (Creator), Kuo, L.-N. (Creator), Wang, W.-C. (Creator), Hsu, Y.-W. (Creator), Wong, H.S.-C. (Creator), Lin, C.-M. (Creator), Liao, K.-H. (Contributor), Zhang, Y.-F. (Creator), Chiang, Y.-H. (Contributor) & Chang, W.-C. (Contributor), Figshare, 2018

  DOI: 10.6084/m9.figshare.c.3983745.v1, https://figshare.com/collections/The_association_between_BDNF_Val66Met_polymorphism_and_emotional_symptoms_after_mild_traumatic_brain_injury/3983745/1

  Dataset

• Additional file 1 of A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies

  Wang, Y.-T. (Creator), Huang, B.-C. (Creator), Hsieh, Y.-C. (Creator), Ho, K.-W. (Creator), Cheng, T.-L. (Creator), Wang, J.-Y. (Creator), Liu, H.-J. (Creator), Tsai, H.-L. (Creator), Liao, J.-M. (Creator), Liu, Y.-L. (Creator), Hong, S.-T. (Creator), Chen, I.-J. (Creator), Su, Y.-C. (Creator) & Chuang, K.-H. (Creator), Figshare, 2022

  DOI: 10.6084/m9.figshare.19101789.v1, https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_A_universal_in_silico_V_D_J_recombination_strategy_for_developing_humanized_monoclonal_antibodies/19101789/1

  Dataset

• MOESM8 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Chung, P.-H. (Contributor), Chen, S.-H. (Contributor), Hsu, T.-I. (Contributor), Liu, M.-S. (Creator), Lo, W.-L. (Creator), Chu, J.-M. (Contributor), Yang, K.-Y. (Creator), Yang, S.-T. (Creator), Liu, J.-J. (Creator), Chuang, J.-Y. (Creator), Yang, W.-B. (Creator), Huang, C.-Y. (Contributor), Chien, C.-H. (Contributor), Chang, K.-Y. (Contributor), Chen, P.-Y. (Contributor) & Chou, S.-W. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006883.v1, https://doi.org/10.6084%2Fm9.figshare.10006883.v1

  Dataset

• MOESM3 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Liu, J.-J. (Creator), Hsu, T.-I. (Contributor), Chou, S.-W. (Creator), Chuang, J.-Y. (Creator), Yang, W.-B. (Creator), Chen, P.-Y. (Contributor), Chen, S.-H. (Contributor), Yang, S.-T. (Creator), Chu, J.-M. (Contributor), Huang, C.-Y. (Contributor), Yang, K.-Y. (Creator), Chien, C.-H. (Contributor), Chung, P.-H. (Contributor), Lo, W.-L. (Creator), Liu, M.-S. (Creator) & Chang, K.-Y. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006856.v1, https://doi.org/10.6084%2Fm9.figshare.10006856.v1

  Dataset

• MOESM1 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Yang, K.-Y. (Creator), Chen, S.-H. (Contributor), Chung, P.-H. (Contributor), Chang, K.-Y. (Contributor), Liu, M.-S. (Creator), Chuang, J.-Y. (Creator), Chien, C.-H. (Contributor), Lo, W.-L. (Creator), Hsu, T.-I. (Contributor), Huang, C.-Y. (Contributor), Chen, P.-Y. (Contributor), Chu, J.-M. (Contributor), Liu, J.-J. (Creator), Yang, S.-T. (Creator), Chou, S.-W. (Creator) & Yang, W.-B. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006847.v1, https://doi.org/10.6084%2Fm9.figshare.10006847.v1

  Dataset

• MOESM5 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

  Liu, J.-J. (Creator), Chen, P.-Y. (Contributor), Chen, S.-H. (Contributor), Chu, J.-M. (Contributor), Chien, C.-H. (Contributor), Yang, W.-B. (Creator), Lo, W.-L. (Creator), Hsu, T.-I. (Contributor), Yang, K.-Y. (Creator), Chung, P.-H. (Contributor), Chou, S.-W. (Creator), Chang, K.-Y. (Contributor), Yang, S.-T. (Creator), Chuang, J.-Y. (Creator), Huang, C.-Y. (Contributor) & Liu, M.-S. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.10006868.v1, https://doi.org/10.6084%2Fm9.figshare.10006868.v1

  Dataset

• Additional file 1: Table S1. of Associations of genetic variants of endothelin with cardiovascular complications in patients with renal failure

  Zhang, Y.-F. (Creator), Cheng, S.-Y. (Creator), Kao, C.-C. (Contributor), Lu, H.-F. (Contributor), Hsu, Y.-W. (Creator), Wu, M.-S. (Creator), Chien, S.-C. (Creator), Wu, M.-Y. (Creator) & Chang, W.-C. (Contributor), Figshare, 2017

  DOI: 10.6084/m9.figshare.c.3874468_d1.v1, https://doi.org/10.6084%2Fm9.figshare.c.3874468_d1.v1

  Dataset

• Additional file 1: of Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

  Wu, M.-Y. (Creator), Nam, S. (Creator), Sun, T. (Creator), Wang, Y.-J. (Creator), Chang, W.-C. (Contributor), Lu, H.-F. (Contributor), Kao, C.-C. (Contributor), Hsu, Y.-W. (Creator), Chien, S.-C. (Creator), Cheng, S.-Y. (Creator) & Wu, M.-S. (Creator), Figshare, 2019

  DOI: 10.6084/m9.figshare.8233763.v1, https://doi.org/10.6084%2Fm9.figshare.8233763.v1

  Dataset

• MOESM7 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

  Wu, J.-Y. (Contributor), Tsai, F.-J. (Contributor), Chen, C.-H. (Contributor), Wong, H.S.-C. (Creator), Lin, Y.-J. (Creator), Lu, H.-F. (Contributor), Liao, W.-L. (Creator) & Chang, W.-C. (Contributor), Figshare, 2019

  DOI: 10.6084/m9.figshare.10270460.v1, https://doi.org/10.6084%2Fm9.figshare.10270460.v1

  Dataset

• Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors

  Su, C.-Y. (Contributor), Chen, M. (Contributor), Chen, L.-C. (Contributor), Ho, Y.-S. (Contributor), Ho, H.-O. (Contributor), Lin, S.-Y. (Contributor), Chuang, K.-H. (Contributor) & Sheu, M.-T. (Contributor), Unknown Publisher, May 2 2018

  DOI: 10.6084/m9.figshare.6213620.v1, https://tandf.figshare.com/articles/Bispecific_antibodies_anti-mPEG_anti-HER2_for_active_tumor_targeting_of_docetaxel_DTX_-loaded_mPEGylated_nanocarriers_to_enhance_the_chemotherapeutic_efficacy_of_HER2-overexpressing_tumors/6213620/1

  Dataset