Projects per year
Organization profile
Organisation profile
宗旨:
促進本校生技醫藥商品化發展,提供一校三院同仁醫藥品研發服務,以開發具有創新性與前瞻性之生技醫藥產品開發為宗旨。
背景:
生技醫藥為我國重要產業,建立藥品及醫材開發的關鍵價值鏈平台是校園研究成果產業化最大的助力。為有效統整及加速本校之新藥及醫材研發能量,規劃成立臺北醫學大學生技醫藥商品化中心(TMU Biomedical Commercialization Center),藉由商品化中心跨院系所專業團隊間的整合運作,提供一校三院同仁生技藥品臨床前到IND申請之臨床前研究(pre-clinical study)諮詢與服務。此外,透過北醫事業發展處協助醫藥品商品化開發策略,包含藥物市場定位分析,法規、專利檢索和諮詢服務,技術轉移或尋求業界承接產學合作案,及衍生新創事業體之相關規劃。
目的:
整合新藥開發及醫療器材從臨床前研究到IND/IDE所需之技術發展平台(Research Development),提供校內外單位委託合作或共同開發之服務。
搭配事業發展處之資源協助擬定生技醫藥品商業化發展策略(Business Development)、專利布局及商業化輔導,以加速產出具有創新性與前瞻性的生技醫藥品。
初期以藥品的商業化平台為目標:規劃由藥物設計/合成與篩選、藥理活性、藥物動力學、藥物代謝、藥效、毒理、小試量產、製劑開發等提供平台服務。
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Network
Profiles
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Wei-Chiao Chang
- Department of Clinical Pharmacy - Professor
- Master Program in Applied Epidemiology - Joint-Appointment Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Professor
- Ph. D. Program in the Clinical Drug Development of Herbal Medicine - Joint-Appointment Professor
- The Ph.D. Program for Translational Medicine - Joint-Appointment Professor
- Ph.D. Program in Medical Neuroscience - Joint-Appointment Professor
- TMU Research Center of Drug Discivery - Member
- TMU Research Center of Cancer Translational Medicine - Member
Person: Researcher
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Chun-Han Chen
- Department of Pharmacology - Associate Professor
- TMU Research Center of Drug Discivery - Member
- TMU Research Center of Cancer Translational Medicine - Member
Person: Researcher
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Mei-Chuan Chen
- Department of Pharmaceutical Sciences - Associate Professor
- Graduate Institute of Pharmacognosy - Joint-Appointment Associate Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Associate Professor
- Ph. D. Program in the Clinical Drug Development of Herbal Medicine - Joint-Appointment Associate Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Associate Professor
- TMU Research Center of Drug Discivery - Member
- TMU Research Center of Thoracic Medicine - Member
Person: Researcher
Projects
- 136 Finished
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DYRK1B於胰臟癌中的轉譯研究與其抑制劑之活體藥效測試
1/1/21 → 12/31/21
Project: B - Project of TMU › h - Higher Education Sprout Project
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合成可雙重抑制組織蛋白去乙醯酶6與熱休克蛋白90,並同時調節PD-L1之雜環類抗癌化合物
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
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標的蛋白降解技術: 含氮三環化合物為骨架利用有機金屬耦合反應合成系列衍生物
8/1/20 → 7/1/21
Project: A - Government Institution › b - Ministry of Science and Technology
Research output
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Application of Design of Experiments in the Development of Self-Microemulsifying Drug Delivery Systems
Hsieh, C. M., Yang, T. L., Putri, A. D. & Chen, C. T., Feb 2023, In: Pharmaceuticals. 16, 2, 283.Research output: Contribution to journal › Review article › peer-review
Open Access -
Comparing the Therapeutic Mechanism and Immune Response of Human and Mouse Mesenchymal Stem Cells in Immunocompetent Mice With Acute Liver Failure
Wang, C. H., Chen, C. Y., Wang, K. H., Kao, A. P., Chen, Y. J., Lin, P. H., Chen, M., Wu, T. Y., Cheng, J. J., Lee, K. D. & Chuang, K. H., Jan 30 2023, In: Stem cells translational medicine. 12, 1, p. 39-53 15 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors
Hsu, J. Y., Hsu, K. C., Sun, C., Chou, C. H., Lin, T. E., Sung, T. Y., Tseng, H. J., Yen, S. C., Yang, C. R. & Huang, W. J., Mar 2023, In: Biomedicine and Pharmacotherapy. 159, 114258.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)
Datasets
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Additional file 1 of Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury
Pan, S. (Contributor), Hsu, K. (Creator), Lin, T. E. (Creator), Lin, C. (Creator), Huang, H. (Contributor) & HuangFu, W. (Contributor), Figshare, 2020
DOI: 10.6084/m9.figshare.11992497.v1, https://doi.org/10.6084%2Fm9.figshare.11992497.v1
Dataset
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MOESM9 of Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning
Wong, H. S. (Creator), Tsai, F. (Contributor), Lu, H. (Contributor), Chang, W. (Contributor), Lin, Y. (Creator), Liao, W. (Creator), Wu, J. (Contributor) & Chen, C. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.10270469.v1, https://doi.org/10.6084%2Fm9.figshare.10270469.v1
Dataset
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Additional file 1 of Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer
Liu, E. (Contributor), Wang, C. (Contributor), Chuang, K. (Contributor), Chen, F. (Creator), Wu, T. (Contributor), Chen, C. (Creator), Chen, I. (Creator), Lin, R. (Creator), Wang, Y. (Contributor), Lu, Y. (Contributor), Liao, T. (Contributor), Chen, H. (Creator), Cheng, T. (Creator) & Cheng, Y. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12885938.v1, https://doi.org/10.6084%2Fm9.figshare.12885938.v1
Dataset