TMU Research Center of Cell Therapy and Regeneration Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2023

• 1 Active
• 452 Finished

Projects per year

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• Antibody-Mediated Immune Suppression of Fetal and Neonatal Alloimmune Thrombocytopenia ( FNAIT)

  Burnouf, T. P. R.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • thrombocytopenia 100%
  • immunoglobulin G 34%
  • antigens 26%
  • antibodies 23%
  • hemorrhage 14%

• Radiogenomics of Malignant Gliomas by Linking Physiological Mr Imaging, Histopathological Patterns, and Genetic Alternations: a Translational Study from Rat to Man

  Chen, C., Tsai, P., Liu, H., Lin, Y. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Glioma 51%
  • Biomarkers 36%
  • Multiparametric Magnetic Resonance Imaging 15%
  • Neoplasms 14%

• The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model

  Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phenserine 100%
  • Stroke 75%
  • Amyloid beta-Protein Precursor 49%
  • Stem Cells 31%
  • pifithrin 27%

• Genomic, Epigenomic and Epiproteomic Analysis of Etk/Bmx Traumatic Brain Injury

  Chen, K., Chiang, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Protein Kinases 15%
  • Epigenomics 14%
  • Tec protein-tyrosine kinase 14%
  • Inflammation Mediators 10%

• Repositioning Drug Therapies for Traumatic Brain Injury

  Chiu, W., Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Wounds and Injuries 37%
  • Dipeptidyl-Peptidase IV Inhibitors 33%
  • Incretins 33%
  • Acetylcysteine 28%

• Effects of Ultrafine Particles on Cardiopulmonary System: a Population-Based Approach

  Chuang, K. & Feng, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Air Pollution 68%
  • Taiwan 34%
  • United States Environmental Protection Agency 33%
  • Organized Financing 13%

• Brain Function for Evaluating Post Stroke Recovery Following Robot-Assisted Gait Training and Transcranial Direct Current Stimulation

  Lai, C., Chen, C., Chen, S., Peng, C., Kang, J. & Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Transcranial Direct Current Stimulation 100%
  • Rehabilitation 95%
  • Stroke 63%
  • Gait 29%
  • Neuroimaging 28%

• Subproject 2---Establishment of a General Multi-Input Multi-Output Platform for Assistive Technology Followed by Developing Individual-Specific Systems: for the Quadriplegic (Themes: E1)

  Chen, S., Peng, C., Pan, L., Jian, W. & Liou, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Education 100%
  • Demonstrations 96%
  • Set theory 75%
  • Feedback 74%
  • Industry 51%

• Development of Cortical Electrical Stimulation Technique for Improving Neuroplasticity and Motor Function in Parkinsonian Rats

  Hsieh, T., Chiang, Y. & Peng, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展國際級之「全方位復健研究中心」(第二年)

  Chen, S.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Valproate治療腦外傷病人的臨床研究

  Chang, C., Chiang, Y., Liao, K., Yang, S., Wu, C. & Chen, K.

  8/7/14 → 8/6/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Traumatic Brain Injury 100%
  • Valproic Acid 97%
  • Therapeutic Uses 31%
  • Histone Deacetylases 29%
  • Glycogen 26%

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( II )

  Chen, S., Lai, C., Ou, K. & Peng, C.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases --Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (II)

  Huang, Y.

  10/1/15 → 9/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具有近紅外光熱效應與螢光影像之奈米金抗癌藥物載體

  Mi, F.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › j - National Taipei University of Technology

• New drug development using dengue virus-infected mouse models(I)

  Lin, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 105年度第二期癌症研究計畫-臺北醫學大學

  Yen, Y., Whang-Peng, J., Liu, L. & Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Neoplasms 100%
  • Breast Neoplasms 71%
  • Antibodies 52%
  • Computational Biology 40%
  • Nicotine 34%

• Development of Ophthalmic Nanomedicine for Corneal Neovascularization Treatment

  Tseng, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Cornea 100%
  • Nanomedicine 81%
  • Eye 59%
  • Nanoparticles 47%
  • Corneal Neovascularization 45%

• 生物矽轉換成中孔生物活性玻璃應用於肌腱骨頭癒合

  Chen, C.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › l - National Taiwan Ocean University

• Implantable Rat ECG Measurement Device Based on Wireless Charge Technique and IMU motion Detection

  Liu, J.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• The Role of Galectin-1 in Fibrosis-promoted Liver Cancer Progression

  Wu, M.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Galectin 1 100%
  • Liver Neoplasms 33%
  • Myofibroblasts 29%
  • Fibrosis 22%
  • Liver Cirrhosis 19%

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 初探以立體列印開發個人化乳癌放療輔具之可行性

  Lu, L.

  1/1/16 → 12/31/16

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Functional Outcomes and Cognitive Interventions in Older People following Traumatic Brain Injury

  Lin, M., Tsai, S., Chen, S., Chiang, Y., Liou, T., Lin, Y. & Shu Kei Lam, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Traumatic Brain Injury 100%
  • Tai Ji 13%
  • Brain Death 11%
  • Executive Function 9%
  • Activities of Daily Living 9%

• 生命科技群組政府科技發展計畫規劃及審議之研究

  Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討精神分裂症藥物之抗乳癌幹細胞潛力與訊息調控機制

  Lin, C.

  3/1/15 → 12/31/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• Establishing Health and Welfare Biotechnology Electronic Database Sharing Platform, Promoting Evidence-Based Medicine and Disseminating Technology Knowledge in Taiwan

  Chen, C., Tam, K., Chen, K., Hou, W. & Bai, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • evidence 76%
  • welfare 56%
  • ministry 47%
  • health 44%

• Investigation of the cerebral perfusion changes in patients with mild traumatic brain injury using 3D bSSFP arterial spin labeling MRI

  Liu, H., Tsai, P., Chen, C. & Lu, C.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 人文思維在科學脈絡的闡發

  Lin, C.

  2/1/16 → 1/31/17

  Project: A - Government Institution › d - Ministry of Education

• 牛樟芝萃取物Antraquinonol對大腸癌幹細胞之抑制潛力與分子標的之探討

  Lin, C.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 神經醯胺生成於麻醉劑異丙酚刺激的巨噬細胞：分子機制與其角色

  Lin, C.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• Application of the Combination of Decelluarized Extracellular Matrix Grafted by Graphene and Bone Marrow Aspirate Concentrates on the Healing of Partial Tear of Anterior Cruciate Ligament

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • anterior cruciate ligament 100%
  • bone marrow 53%
  • extracellular matrix 44%
  • concentrates 35%
  • graphene 28%

• 肺部炎症暨纖維化之轉譯研究

  Lin, C.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Role of Amyloid-Beta in the Late-Onset Post-Stroke Vascular Cognitive Impairment( II )

  Hu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cell Sheet Engineering for Primary Corneal Endothelial Cells and Its Animal Model

  Tseng, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endothelial Cells 100%
  • Transplants 31%
  • Cornea 31%
  • Polyglutamic Acid 27%
  • polyvinylidene fluoride 26%

• Molecular Mechanism of the Effect of Cafestol on Growth Factor-Induced Cardiomyocyte Hypertrophy

  Liu, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cafestol 100%
  • urotensin II 55%
  • Cardiac Myocytes 49%
  • Hypertrophy 40%
  • Intercellular Signaling Peptides and Proteins 21%

• Anti-Aging Effect with the Associated Mechanism by PRP (Platelet-Rich Plasma) in Cartilage---A Fibronectin Fragment Model(3/3)

  Lee, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • cartilage 63%
  • Toll-like receptor 2 58%
  • osteoarthritis 50%
  • chondrocytes 42%

• Mri Study on Trans-Neuronal Degeneration of the Thalamic Networks after Ischemic Stroke

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thalamus 100%
  • Stroke 96%
  • Thalamic Nuclei 52%
  • Cerebral Infarction 43%
  • Gait 38%

• Characterization of Thalamocortical Dysrhythmia in Mild Traumatic Brain Injury Using Simultaneous Mri and Eeg Measurements and Pre-Clinical N-Acetylcysteine Treatment Response

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylcysteine 44%
  • Post-Concussion Syndrome 17%
  • Neuroimaging 15%
  • Electroencephalography 14%
  • Atrophy 9%

• Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring(3/3)

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fetal Growth Retardation 100%
  • Hyperoxia 99%
  • Receptor for Advanced Glycation End Products 74%
  • Epigenomics 69%
  • Lung 48%

• Radiogenomics of Malignant Gliomas by Linking Physiological Mr Imaging, Histopathological Patterns, and Genetic Alternations: a Translational Study from Rat to Man(2/3)

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Glioma 51%
  • Biomarkers 36%
  • Multiparametric Magnetic Resonance Imaging 15%
  • Neoplasms 14%

• The Studies of Cxcl12 on Mycobacterium Tuberculosis-Induced Fibrocyte Activation and Pulmonary Fibrosis

  Lin, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Fibrosis 100%
  • Mycobacterium tuberculosis 84%
  • Tuberculosis 80%
  • Myofibroblasts 49%
  • Connective Tissue Growth Factor 43%

• 幹細胞基礎研究與前臨床動物試驗

  Huang, Y.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Platelets and Platelet-Derived Microparticles for Trojan Horse Cancer Therapy (THCt)(2/3)

  Burnouf, T. P. R.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • doxorubicin 100%
  • microparticles 83%
  • cancer therapy 31%
  • drug carriers 16%
  • neoplasms 16%

• The Functional Role of Pdk1 in Arnt Oncogene-Regulated Tumorigenesis and Tumor Progression

  Chang, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasms 100%
  • Enzymes 90%
  • Carcinogenesis 47%
  • Oncogenes 39%
  • Neoplasm Metastasis 38%

• To Study the Role of Sp1 in Cancer Metastatic Progression( I )

  Chang, W.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasms 100%
  • Neoplasm Metastasis 39%
  • Transcriptome 23%
  • Stomach Neoplasms 22%
  • Lung Neoplasms 20%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Make a Portable/Wearable Kidney Possible – Development of Microtube Array Membrane (Mtam) Dialyzer – Study on Uremic Toxins Removal

  Wu, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Membranes 100%
  • Dialysis 95%
  • Equipment and Supplies 66%
  • Artificial Kidneys 55%
  • 4-cresol sulfate 34%

• Kaempferol Contained Nanomedicine as Eye-Drop for Corneal Neovascularization Treatment : Formulation, Anti-Angiogenesis Mechanism and Therapeutic Outcome Evaluation

  Tseng, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cornea 100%
  • Nanomedicine 81%
  • Eye 52%
  • Ophthalmic Solutions 50%
  • Nanoparticles 47%

• The New Therapeutic Strategy of 2, 3, 5, 4’-Tetrahydroxystilbene-2-O-Β-D-Glucoside (Thsg) Derivatives on Human Dental Pulp Stem Cells-Based Periodontal Treatment

  Lee, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • resveratrol 100%
  • stem cells 59%
  • therapeutics 55%
  • tooth pulp 53%
  • cell proliferation 42%