TMU Research Center of Cell Therapy and Regeneration Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2024

• 1 Active
• 453 Finished

Projects per year

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• Active

  生殖系幹細胞的多能性調控: 探討SATB2, IGF-1R, 和 Laminin微環境間的相互作用對於細胞命運的影響(延續型計畫)(1/3)

  Kuo, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Finished

  Regulation of Pluripotency in Germline Stem Cells: the Effect of Crosstalk between Satb2, Igf-1r, and Laminin Niches on Cell Fate Determination

  Kuo, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 探討Lenvatinib合併使用IGF-1R抑制劑 Linsitinib逆轉抗Sorafenib肝癌抗藥性的機制

  Kuo, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 2-1-1 發展居國際領先地位之研究領域-癌症轉譯研究中心業務費

  Yen, Y.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 以α9-尼古丁受體作為分子標靶探討國人乳癌發生之風險暴露及抗體藥物研發與臨床前試驗評估(第4年)

  Yen, Y.

  1/1/21 → 12/31/21

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 人類胎盤間質幹細胞(在急性肺損傷與氣喘中對於纖維細胞分化、遷徙、免疫調控之研究)

  Kuo, Y.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 110年度高等教育深耕計畫第2部分-特色領域研究中心計畫

  Yen, Y.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新聘教師研究補助

  Kuo, Y.

  10/1/20 → 9/30/21

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 藉由檢測細胞免疫分型預測膀胱癌病人接受溫熱治療的療效

  Shih, H.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 109年度高等教育深耕計畫第2部分-特色領域研究中心計畫

  Yen, Y.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 2-1-1 發展居國際領先地位之研究領域-癌症轉譯研究中心業務費

  Yen, Y.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 人類胎盤間質幹細胞(在急性肺損傷與氣喘中對於纖維細胞分化、遷徙、免疫調控之研究)

  Kuo, Y.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 發展標靶CEACAM6的口腔癌治療診斷方法

  Wu, M.

  1/1/20 → 12/31/20

  Project: A - Government Institution › a - National Health Research Institutes

• 以α9-尼古丁受體作為分子標靶探討國人乳癌發生之風險暴露及抗體藥物研發與臨床前試驗評估(第3年)

  Yen, Y.

  1/1/20 → 12/1/20

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 臺北醫學大學自有貴重儀器共同使用服務計畫

  Huang, Y.

  12/1/19 → 12/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Antibody Repertoire in Mycobacterium Tuberculosis Infection: Investigate Functional Immunoglobulins in Tb Infection and Translational Applications

  Tsai, I.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Hbx and Its Associated Epigenetic Regulators in Promoting Senp1 Expression and Cancer Stemness in Hbv-Related Hepatocellular Carcinoma: the Role of Hbx/Senp1 and Its Clinical Impact(2/3)

  Wu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(2/3)

  Wu, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Novel D2r Heteroreceptor Complexes as Anti-Dengue Strategy by Interfering Viral Infection and Immunopathogenesis

  Lin, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.( II )

  Huang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Mechanisms for Epithelium-Derived Interleukin 33 (Il-33) Up-Regulation and Its Effects on Circulating Fibrocyte Chemotaxis, Proliferation and Differentiation in Patients with Chronic Obstructive Asthma(3/3)

  Kuo, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Investigation of Anti-Neuroinflammatory Constituents from Fungal Species and Their Protective Profiles in the Retinal Diseases(2/3)

  Hsiao, G.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Role of high cell density in pIGF1R/EpCAM-induced Sorafenib resistance in HBV-HCC

  Huang, Y.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - National Science and Technology Council

• 細胞損傷誘導之半乳糖凝集素-3在肺纖維化中促進乙型轉型生長因子誘導之間質轉化

  Lin, C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - National Science and Technology Council

• Systemic Safety Allograft Strategies for Cell Therapeutic Product Development: Targeting Unmet Medical Need Human Chronic Inflammatory Disease - Diabetes Mellitus /Decubitus Wound, Severe Burn, and Multiple Sclerosis( III )

  Huang, Y.

  5/1/19 → 4/1/20

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Shih, H.

  5/1/19 → 4/30/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 推動新南向醫衛合作與產業鏈發展

  Kuo, H.

  2/11/19 → 12/11/19

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 藉由檢測自然殺手細胞的活性預測膀胱癌病人接受溫熱治療的療效

  Shih, H.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-應用蛋白代謝體學探討胎盤絨毛膜蛻膜間質幹細胞與肺纖維細胞交互作用及其療效機制

  Tsai, I.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-探討人類胎盤間質幹細胞調控肺纖維母細胞活化及肺組織纖維化的角色

  Wu, M.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-人類胎盤間質幹細胞於治療老化相關急性肺損傷之探討：安全性、有效性、與細胞產品之開發

  Huang, Y.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 人性化的網路平台協助醫學資訊管理與報表產出-放射治療自動繪圖系統的數據驅動機器學習策略

  Shih, H.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-開發人類胎盤間質幹細胞(pcMSCs)之細胞治療產品-細胞庫與品質管控建立

  Wu, Y.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• PM2.5對慢性阻塞性肺病在肺修復和再生受損的影響-IL-17和新穎生物標記在環境PM2.5誘導COPD肺損傷的影響

  Lee, K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 神經內分泌型前列腺癌的轉譯研究-L1CAM在神經內分泌型前列腺癌的轉譯研究

  Hsieh, C.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-人類胎盤間質幹細胞治療於急性肺損傷誘發肺纖維化之免疫校訂監測與調節

  Lin, C.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 癌症病人免疫治療前後之免疫監測

  Lee, K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發-3

  Lin, C.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發-3

  Lin, C.

  10/1/18 → 12/1/18

  Project: A - Government Institution › d - Ministry of Education

• 國際產學聯盟計畫II

  Lin, C.

  9/1/18 → 11/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• Decellularized Plant Extracellular Matrices as a Scaffold for Tissue Engineering(2/2)

  Tseng, H.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • extracellular matrix 100%
  • animal tissues 65%
  • tissue engineering 44%
  • porometers 29%
  • polyglutamic acid 28%

• The Effects of Melatonin on Proliferation, Osteogenic Differentiation and in Vivo Bone Regeneration of Dental Pulp-Derived Mesenchymal Stem Cells and Related Molecular Mechanisms

  Feng, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • mesenchymal stromal cells 100%
  • melatonin 88%
  • tooth pulp 57%
  • bones 52%
  • stem cells 45%

• The Role of Galectin-3 in Ceacam6 Enhanced Egfr Signaling and Its Implication in Head and Neck Cancer Therapy

  Wu, M.

  8/1/18 → 7/30/20

  Project: A - Government Institution › b - National Science and Technology Council

  • Carcinoembryonic Antigen 100%
  • Cell Adhesion Molecules 98%
  • Galectin 3 64%
  • Squamous Cell Carcinoma of Head and Neck 43%
  • Cetuximab 24%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Trajectory and Biomarkers for Post-Stroke Cognitive Impairment(1/3)

  Hu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• To Study the Role of Sp1 in Cancer Metastatic Progression(3/3)

  Chang, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Application of the Combination of Decelluarized Extracellular Matrix Grafted by Graphene and Bone Marrow Aspirate Concentrates on the Healing of Partial Tear of Anterior Cruciate Ligament(3/3)

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - National Science and Technology Council

  • anterior cruciate ligament 100%
  • bone marrow 53%
  • extracellular matrix 44%
  • concentrates 35%
  • graphene 28%