TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2023

• 6 Active
• 535 Finished

Projects per year

Search results

• Finished

  魚油多元不飽和脂肪酸對胰臟癌細胞脂質代謝與癌轉移之研究

  Chiu, C.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Strategy for Treatment of Osimertinib-Resistant Lung Adenocarcinoma by Jnk Activation

  Yao, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Carcinogenic Mechanisms of Serine/Threonine-Protein Kinase (Sik3) Involved in the Process of Breast Tumor Formation

  Chen, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting O-Glycans of Iga1 to Develop Diagnostic Reagents for Iga Nephropathy and Reshape Its Clinical Assessment Protocol( III )

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Immunoglobulin A 100%
  • Clinical Protocols 35%
  • Taiwan 35%
  • Polysaccharides 33%
  • Therapeutics 5%

• Identify Human Surfaceome in Deep Learning for Cell-Type Annotation and Isolation from Scrna-Seq

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以IgA1 O-聯結醣基為標靶開發IgA腎病變之診斷試劑重塑臨床評估之準則(2/3)

  Lee, Y.

  8/1/20 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米HEVnp於晚期大腸直腸癌患者的治療策略(2/3)

  Whang-Peng, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of the Hdacs/Sp1-Mediated Microrna-106b~25 Axis in Drug Resistance of Glioblastomas(1/3)

  Chen, R.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Mechanisms of Histamine N-Methyl-Transferase (Hnmt) as a Novel Molecular Marker to Help Clinician for Identifying of Herceptin Responder in Breast Cancer Patients(1/3)

  Ho, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Translational Study to Verify Roles of Circulating Mir-19b and Mir-93 as Biomarker Signatures for Early Diagnosis of Osteoporosis in Men(2/3)

  Chen, R.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Mechanism of Cd155/Tigit in Mdsc/Tam Induced Nk Cell Dysfunction -A Link to Lung Cancer Resistance to Immune Checkpoint Blockade

  Feng, P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Leukemia Based Precision Medicine Research Model on Non-Invasive Apoptosis Detection Platform – Application of Crispr/Cas9 Gene and Target Therapy on Philadelphia Chromosome of Chronic Myelogenous Leukemia as an Example

  Chen, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Precision Medicine 100%
  • Leukemia 88%
  • Heterografts 41%
  • Philadelphia Chromosome 39%
  • Myeloid Leukemia 37%

• Synthetic and Medicinal Utility of Organometallics in the Development of Anticancer Epigenetic Inhibitors: Applications and Explorations( I )( I )(1/2)

  Liou, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Nano-Hevnp Theranostic Strategy for Late-Stage Colorectal Cancer Patients(1/3)

  Whang-Peng, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Develop Novel Treatment Options for Hepatocellular Carcinoma via Drug Repurposing(2/2)

  Whang-Peng, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Oncogenic Roles of A9-Nicotinic Acetylcholine Receptor Variants on Breast Cancer( III )

  Ho, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Role of Gut Microbiota in Antipsychoticinduced Metabolic Dysfunction in Patient with Schizophrenia

  Liu, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 調節第一型神經衍生孤兒核受體 (Neuron-derived orphan receptor 1, NOR-1)之蛋白質表現可能是 Pomalidomide對創傷性腦損傷之神經保護作用之一

  Chen, R.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 激肽釋放酶-激肽系統調控惡性神經膠質瘤細胞基質金屬蛋白酶表現之機轉

  Chen, R.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 21121 發展特色研究，推動轉譯醫學（CRISPR基因編輯核心實驗室）

  Chu, C.

  1/1/19 → 12/31/19

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 神經內分泌型前列腺癌的轉譯研究-ADAM9在神經內分泌型前列腺癌的轉譯研究

  Sung, S.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 亞太生醫矽谷精準醫療旗艦計畫-臺北醫學大學合作案

  Liou, J.

  1/1/19 → 12/1/19

  Project: A - Government Institution › a - National Health Research Institutes

• 具抗藥性多形性膠質母細胞瘤的新穎治療策略研究-Bradykinin-TIMP-MMP 軸在抗藥性神經膠質瘤細胞調控血瘤障壁通透性過程中扮演的角色

  Chen, R.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Repurposing of a Positive Allosteric Modulator of M5 Muscarinic Acetylcholine Receptor as a Microtubule-Targeting Agent and Its Application for Treating Pancreatic Ductal Adenocarcinoma

  Hsieh, Y.

  1/1/19 → 6/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展抗肺纖維化劑-合成抗肺纖維化合物

  Liou, J.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 探討CD155/TIGIT 在類骨髓衍生抑制細胞/腫瘤衍生巨噬細胞誘導自然殺手細胞失調的機轉- 研究肺癌病人免疫檢查點阻斷藥物抗藥性機轉

  Feng, P.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• PM2.5對慢性阻塞性肺病在肺修復和再生受損的影響-IL-17和新穎生物標記在環境PM2.5誘導COPD肺損傷的影響

  Lee, K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 雙打擊在瀰漫大B細胞淋巴瘤所扮演的角色-致病機轉與臨床特色之探討-JARID1B蛋白在雙打擊瀰漫大B細胞淋巴瘤的角色及其臨床定義

  Liu, Y.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of High-Throughput Sequencing Approaches in Immunogenomic Research : Diversity and Clonal Selection in the Human T-Cell Repertoire for Colonrectal Cancers(3/4)

  Chang, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)(1/3)

  Chien, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Mirna and Gut Microbiota in Pathogenesis of Post-Stroke Vascular Cognitive Impairment

  Chiou, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Environmental Factors and Genetic Polymorphisms Associate with the Development and Prognosis of Oral Squamous Cell Carcinoma

  Yeh, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Squamous Cell Carcinoma 100%
  • Genes 26%
  • Taiwan 21%
  • DNA Repair 20%
  • Genome 14%

• Investigation of Hmga2-Microrna Regulatory Network to Tune Oncogenesis

  Huang, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • MicroRNAs 16%
  • Colorectal Neoplasms 12%
  • Carcinogenesis 9%
  • Neoplasms 7%

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells(3/3)

  Ho, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 16%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• Investigation of Role of Adam17/Preadipocyte Factor-1 in Hypoxia-Induced Ctgf Expression and Airway Fibrosis(1/3)

  Chen, B.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Sp1 in Cancer Drug Resistance(3/3)

  Chuang, J.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Develop Novel Treatment Options for Hepatocellular Carcinoma via Drug Repurposing(1/2)

  Whang-Peng, J.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Nano-Diamino-Tetrac (Ndat) Enhances Resveratrol-Induced Anti-Proliferation by Action on the Rrm2 Pathway in Colorectal Cancers

  Lin, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • Ribonucleotide 49%
  • Antiproliferative 13%
  • Bellow 10%
  • Stilbenoid 10%

• Drug Discovery and Pharmacological Investigation of Novel Selective Hdac Inhibitors as Anticancer Drugs(1/3)

  Pan, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腸道菌相在抗精神病藥物誘發思覺失調症患者代謝症候群之作用

  Liu, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Gastrointestinal Microbiome 100%
  • Antipsychotic Agents 74%
  • Schizophrenia 49%
  • Treatment Adherence and Compliance 46%
  • Metabolic Diseases 42%

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X(2/3)

  Wang, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Pctk1 in the Progression of Colorectal Cancer and Molecular Mechanism (Continuation Project)(1/3)

  Wei, P.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Studies on the Mechanisms of Dna Primase（Prim1）Involved in Smoking-Induced Breast Cancer Formations and Its Translational Applications

  Chen, L.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Generate Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Gastric Cancer

  Lee, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Angiopoietin-Like Protein 1 in Sorafenib Resistance and Cancer Stemness of Hepatocellular Carcinoma Cells

  Huang, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Angiopoietin-like Proteins 100%
  • Sorafenib 97%
  • Hepatocellular Carcinoma 53%
  • Gastropoda 44%
  • Neoplasms 17%

• A Translational Study to Verify Roles of Circulating Mir-19b and Mir-93 as Biomarker Signatures for Early Diagnosis of Osteoporosis in Men

  Chen, R.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Dyrk1a Inhibitors for the Treatment of Alzheimer'S Disease

  HuangFu, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dyrk kinase 100%
  • Alzheimer Disease 43%
  • Neurofibrillary Tangles 17%
  • Amyloid beta-Peptides 15%
  • Memory 10%