TMU Research Center of Cancer Translational Medicine

Projects

Projects per year 2010 2014 2015 2016 2017 2018 2023

• 6 Active
• 535 Finished

Projects per year

Search results

• Finished

  Role and Molecular Mechanisms of a Disintegrin and Metalloproteinase with Thrombospondin Motif 1 in Melatonin-Mediated Invasive and Metastatic Abilities of Renal Cell Carcinoma

  Wen, Y.

  12/1/17 → 11/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 大數據應用分析人才培訓計畫

  Chiou, H.

  12/1/17 → 11/30/18

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 選擇性抗癌標靶藥物HDAC6抑制劑臨床前試驗研究

  Pan, S.

  12/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 子宮內膜癌分子篩檢試劑套組開發案

  Lai, H.

  12/1/17 → 5/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 整合式篩檢問卷及生化檢驗值統計分析案

  Chen, L.

  11/20/17 → 12/10/17

  Project: A - Government Institution › f - Other (Funded by Government)

• 新聘教師研究補助

  Huang, C.

  10/1/17 → 9/30/18

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 新聘教師研究補助

  Tzeng, H.

  10/1/17 → 9/30/18

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Investigation of Inflammatory Microenvironment-Regulated Stemess in Glioblastoma

  Ko, C.

  10/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • CCAAT-Enhancer-Binding Protein-delta 100%
  • Glioma 36%
  • Gallbladder Neoplasms 11%
  • Neoplastic Stem Cells 9%
  • Glioblastoma 8%

• 106年度委託科技研究計畫－運用資通訊科技以提升健康照護服務效能－分項5：健康資訊科技之國際合作研究

  Li, Y.

  8/23/17 → 4/22/18

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Telemedicine 100%
  • Learning Health System 90%
  • Information Technology 85%
  • Delivery of Health Care 65%
  • Technology 58%

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy

  Tsai, K. K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Antitumor Activity and Pharmacological Mechanisms of Pik3c3 Inhibitor in Bladder Cancer Cells

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Urinary Bladder Neoplasms 100%
  • Autophagy 72%
  • Endosomes 31%
  • Cachexia 23%
  • Phosphatidylinositol 3-Kinases 18%

• The Association of Nonage Chronic Arsenic Exposure, Methylation Levels of Arsenic Metabolism Genes, and the Risk of Cancer Development

  Chiou, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • arsenic 100%
  • adulthood 37%
  • neoplasms 27%
  • methylation 24%
  • metabolism 15%

• 腦血流調控功能在腦血管疾病及神經退化性疾病的角色及應用

  Chiou, H.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia( III )

  Chiou, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma

  Chien, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• The Encapsulated Cell Therapy via a Novel Microtube Array Membrane Encapsulated Hybridoma for Cancer Immunotherapy

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Immunotherapy 100%
  • Membranes 81%
  • Hybridomas 77%
  • Cell Survival 51%
  • Neoplasms 43%

• Drug Discovery and Pharmacological Investigation of Selective Hdac1 and 2 Inhibitors as Novel Anticancer Drugs

  Pan, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Antitumor 34%
  • Antineoplastic Agent 33%
  • Drug 29%
  • DNA Sequence 19%

• Disease Trajectories and Its Association with Metabolic Dysfunction of Prostate Cancer Men Following Androgen Deprivation Therapy and the Potential of Pharmacological Medication in Preventing Metastatic Diseases.

  Shao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Pctk1 in the Progression of Colorectal Cancer and Molecular Mechanism

  Wei, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • colorectal neoplasms 100%
  • neoplasms 54%
  • therapeutics 39%
  • metastasis 39%
  • death 31%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Therapeutic Potentials of Peptide-Based Cytokine Binding Decoy against Sepsis and Its Effects on Modulating Inflammation, Oxidation, Apoptosis, Autophagy and Inflammasome

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sepsis 100%
  • Peptides 37%
  • Cytokine Receptors 31%
  • Cytokines 24%
  • Inflammasomes 23%

• Apply Human Cell Lines and Mice Model to Study Novel Bio-Adhesive Nanomaterials in Anti-Aging and Skin Cancer Prevention.

  Cho, E.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antiaging 100%
  • Reactive Oxygen Metabolite 97%
  • Bioadhesive 97%
  • Fullerene 94%
  • Free Radical 82%

• Primase, DNA, polypeptide 1（PRIM1)參與吸菸所誘發乳癌形成機制及臨床轉譯研究(1/3)

  Chen, L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Discovering Blood Circulating and Bone Micrornas as Biomarker Signatures for Diagnosis or Therapy of Osteoporosis in Men and Male Osteoporotic Fracture

  Chen, R.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteoporosis 100%
  • microRNA 57%
  • bones 36%
  • biomarkers 27%
  • bone fractures 19%

• Studies on the Role of Stomatin-Like Protein 2 (Stoml2) in Thrombin-Stimulated Il-8/Cxcl8 Expression and Airway Inflammation

  Chen, B.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Angiopoietin-Like Protein 1 in Sorafenib Resistance and Cancer Stemness of Hepatocellular Carcinoma Cells

  Huang, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Angiopoietin-like Proteins 100%
  • Sorafenib 97%
  • Hepatocellular Carcinoma 53%
  • Gastropoda 44%
  • Neoplasms 17%

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 17%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X

  Wang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular and Translational Study of L1cam in Metastatic Castraction Resistant Prostate Cancer (Mcrpc)

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Cell Adhesion Molecule L1 100%
  • Prostatic Neoplasms 37%
  • Radiation 14%
  • Phosphorylation 13%
  • Bone Neoplasms 11%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• A Preclinical Study of the Therapeutic Targeting of Inflammatory-Cytokine-Addicted Cancer Stem Cells in Advanced Pancreatic Cancer

  Tsai, K. K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臨床藥物基因體科技在血管支架再阻塞的預測及藥物開發之應用(先期補助)

  Chang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• Dissected the Role of Thrombomodulin in the Clinical Diagnostic and Therapeutic Impacts for Breast Cancer and the Regulation Mechanisms

  Hung, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thrombomodulin 100%
  • Breast Neoplasms 90%
  • Therapeutics 20%
  • Neoplasms 12%
  • Steroid Receptors 11%

• To Study the Role of Sp1 in Cancer Drug Resistance( II )

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Hdac6-Mediated Sp1 Deacetylation in the Evolution of Acquired Temozolomide Resistance in Glioblastoma

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase 6 100%
  • Temozolomide 84%
  • Glioblastoma 54%
  • Vorinostat 26%
  • Methyltransferases 20%

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression

  Chen, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Measure of Palliative Care Spiritual Care Competency and the Effectiveness of an Educational Program for Palliative Spiritual Care Providers

  Chiou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Palliative Care 100%
  • Program Evaluation 46%
  • Education 32%
  • Research Design 24%
  • Learning 15%

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development

  Hsu, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• The Role of Egfr in Prostate Cancer Progression and Combination Therapy

  Liu, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 75%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• 幹細胞基礎研究、前臨床動物試驗與臨床試驗

  Huang, Y.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Investigating the Oncogenic Roles of A9-Nicotinic Acetylcholine Receptor Variants on Breast Cancer( I )

  Ho, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents.( I )

  Liou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Chan-Lam Coupling 96%
  • Buchwald-Hartwig Cross Coupling Reaction 79%
  • Ullmann Reaction 76%
  • Alkynylation 75%

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skeletal Muscle 100%
  • Sarcopenia 58%
  • Regeneration 52%
  • Muscles 47%
  • Muscular Diseases 33%

• Application of High-Throughput Sequencing Approaches in Immunogenomic Research : Diversity and Clonal Selection in the Human T-Cell Repertoire for Colonrectal Cancers

  Chang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • T-Cell Antigen Receptor 54%
  • V(D)J Recombination 52%
  • T-Lymphocytes 44%
  • Neoplasms 28%

• Investigation of the Role and Underlying Mechanism of Methylenetetrahydrofolate Dehydrogenase 2(Mthfd2) in the Cancer Stem Cell Properties and Tumorigenesis of Lung Cancer

  Deng, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methylenetetrahydrofolate Dehydrogenase (NADP) 100%
  • Neoplastic Stem Cells 29%
  • Lung Neoplasms 27%
  • NAD 21%
  • Serine 20%

• Tumor Microenvironment Induced Egfr-Tki Resistance

  Feng, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ErbB Receptors 100%
  • Adenocarcinoma of Lung 37%
  • Macrophages 36%
  • Tumor Microenvironment 36%
  • Neoplasms 33%

• 藉由虛擬實境提升高齡者身心健康

  Li, Y.

  8/1/17 → 7/31/18

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Hmga2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 82%
  • tetraiodothyroacetic acid 76%
  • Colorectal Neoplasms 47%
  • Catenins 34%

• Personzliaed Periodontal Disease Prevention

  Chen, L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Risk assessment 100%
  • Microorganisms 61%
  • History 60%
  • Medical problems 56%
  • Medicine 51%