TMU Research Center of Biomedical Devices

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2021

• 425 Finished

Projects per year

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• Production of polyclonal IgY and monoclonal scFv antivenom antibodies against Formosan venomous snakes and their potential applications

  Yang, Y.

  8/16/10 → 12/31/10

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • antibodies 100%
  • venoms 94%
  • horses 48%
  • immunoglobulin Y 38%
  • antivenoms 31%

• Reconstruction of Vertebral Body with Delayed Posttraumatic Vertebral Collapse---Biomechanical Evaluation and Redesign

  Chen, H.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • vertebrae 100%
  • mechanical testing 50%
  • spine (bones) 47%
  • surgery 43%
  • bones 36%

• Investigation of the Feasibility of Functional Electrical Stimulation in the Treatment of Bladder Dysfunction under a Diabetic Rat Model

  Peng, C. & Chen, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Urinary Bladder 100%
  • Electric Stimulation 83%
  • Urinary Tract 45%
  • Neurogenic Urinary Bladder 14%
  • Anal Canal 12%

• Cell Behaviors and Its Gene Analysis of Nerve-Like Cell on Three-Dimensional Fibrous Matrix

  Tseng, H. & Ho, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • membranes 100%
  • nerves 70%
  • cells 60%
  • gene expression 50%
  • tissue engineering 32%

• The Characterisitc of Trapezius Surface Myography during Sleep

  Kang, J., Hu, C., Chen, S. & Tseng, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Superficial Back Muscles 100%
  • Myalgia 51%
  • Sleep 36%
  • Posture 8%
  • Myofascial Pain Syndromes 6%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Li, Y., Yang, W., Shen, S. & Kao, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• Application for Surface Modification and Patterns of Bio-Medical Degradable Material on Nano Forming Technology Using Anodic Alumina Oxide Template (II)

  Shen, Y. & Huang, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Plastic products 100%
  • Aluminum oxide 58%
  • Blood vessel prostheses 38%
  • Animals 26%
  • Electroforming 20%

• The Role and Molecular Mechanism of Urotensin II in Renal Disease: Focus on Tubular Injury and Renal Fibrosis

  Hsu, Y., Chen, T. & Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • urotensin II 100%
  • Kidney 27%
  • Fibrosis 11%
  • Wounds and Injuries 10%
  • Renal Insufficiency 8%

• Effect of Bright Light Therapy on Improving Sleep Disburanbce and Its Clustered Symptoms in Cancer Patients

  Lin, C., Lee, H., Shiau, F., Lai, Y. & Lin, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Phototherapy 40%
  • Neoplasms 26%
  • Light 14%
  • Sleep Initiation and Maintenance Disorders 14%

• Investigation on the Effects of Smf on the Promotion of Neuritogenesis and Inhibition of Neurodegeneraton

  Huang, H.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Magnetic Fields 100%
  • Microglia 35%
  • Neurodegenerative Diseases 30%
  • Lipopolysaccharide Receptors 25%
  • Catalogs 21%

• Sleep Disturbances in Methadone Maintenance Treatment---A Case-Control Study

  Lee, H. & Kang, J.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methadone 100%
  • Sleep 45%
  • Mental Disorders 23%
  • Case-Control Studies 23%
  • Central Sleep Apnea 20%

• Development of Novel Dna Methyltransferases Inhibitors for Breast Cancer Treatment

  Lin, R. & Huang, W.

  1/1/11 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • mithramycin A 100%
  • mithramycin SK 42%
  • Tumor Suppressor Genes 37%
  • Neoplasms 32%
  • CpG Islands 22%

• Impact of Internet Use on Sleep Quality and Autonomic Nervous System in Elementary School Children and the Effect of Cognitive Behavioral Treatment

  Chen, S., Jeng, C., Lee, H. & Shiau, F.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autonomic Nervous System 100%
  • Internet 77%
  • Sleep 47%
  • Cognitive Behavioral Therapy 31%
  • Heart Rate 29%

• Development of Hydrophilic Electrospun (Es) PLA/Bioceramic Guided Tissue/Bone Regeneration (GT/GBR) Membranes

  Lee, S. & Yang, J.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bones 100%
  • clinical trials 50%
  • periodontal diseases 32%
  • animal tests 28%
  • biocompatibility 27%

• 100年度「轉譯醫學及農學人才培育先導型計畫」

  Lee, S., Huang, Y. & Yang, J.

  1/1/11 → 12/31/11

  Project: A - Government Institution › d - Ministry of Education

• An Integrated Program for Evaluation, Risk factors, and Intervention of Mental Health among Antepartum and Postpartum Women in Taiwan

  Chen, Y., Chen, P., Hsu, C. & Lee, H.

  1/1/11 → 12/31/11

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Depression 100%
  • Mothers 69%
  • Pregnant Women 44%
  • Taiwan 43%
  • Psychiatric Status Rating Scales 42%

• Characterization of single chain variable fragment (scFv) antibodies against snake venoms from chickens with high titers of anti-venom IgY antibodies

  Yang, Y. & Leu, S.

  1/1/11 → 12/31/11

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • antibodies 100%
  • venoms 77%
  • snake venoms 36%
  • polyclonal antibodies 31%
  • antivenoms 30%

• A development plan for the immunodiagnostic kit of endometriosis

  Yang, W.

  5/1/11 → 4/30/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • blood serum 100%
  • patents 77%
  • analytical kits 70%
  • antibodies 46%
  • biomarkers 32%

• The Research of Core Course for Bio-Energy in TMU

  Shen, Y.

  11/1/10 → 6/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bioenergy 100%
  • biofuel 50%
  • renewable resources 20%
  • SPSS 14%
  • student 12%

• The Causes and Courses of Insomnia---Case-Control and Follow-up Study

  Lee, H., Hsu, R. & Kang, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep Initiation and Maintenance Disorders 100%
  • Sleep 24%
  • Organized Financing 18%
  • Arousal 15%
  • Case-Control Studies 12%

• Development a Tissue-Like Block by Novel Porous Calcium Phosphate Combined Dental Pulp Stem Cells and Platelets Rich Fibrin for Bone Regeneration in Large Bony Defect

  Lee, S. & Yang, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium phosphate 100%
  • Stem cells 80%
  • Pulp 61%
  • Bone 54%
  • Platelets 43%

• Development of Dna Methyltransferases Inhibitors from Natural Products for Target Therapy of Lung Cancer

  Lin, R.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • mithramycin A 100%
  • Tumor Suppressor Genes 56%
  • DNA Methylation 28%
  • Lung Neoplasms 22%
  • Tissue Inhibitor of Metalloproteinase-3 21%

• Research of Wear Resistance and Biocompatibility on Dental Drills Surface with TiAlN Films

  Huang, M.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Biocompatibility 100%
  • Biomedical equipment 44%
  • Thin films 38%
  • Stainless steel 35%
  • Copper 33%

• Effect of Bright Light Therapy on Improving Sleep Disburanbce and Its Clustered Symptoms in Cancer Patients

  Lin, C., Shiau, F., Lai, Y., Lin, C. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Phototherapy 40%
  • Neoplasms 26%
  • Light 14%
  • Sleep Initiation and Maintenance Disorders 14%

• Quantifying the Thermodynamic Profiles of the Interaction between Small Molecules and Nucleic Acids by Single Molecule Techniques

  Yang, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Drug 100%
  • Thermodynamics 97%
  • Kd 95%
  • Gibbs Free Energy 71%
  • Nucleic Acid 53%

• Increasing Cryopreservative Efficiency of Therapeutic Cells by Coupling a Strong Static Magnetic Field during Freezing Process

  Huang, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • magnetic fields 100%
  • freezing 36%
  • cells 33%
  • thawing 32%
  • natural killer cells 26%

• Functional Evaluation of Extracts and Pure Compounds Isolated from VI Tis Thunbergii Var. Taiwaniana on the Improvements of Metabolic Syndrome-Related Diseases

  Hou, W., Liu, D. & Liang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vitis ficifolia 100%
  • metabolic syndrome 58%
  • diabetes 45%
  • extracts 33%
  • cardiovascular diseases 23%

• Preparation and Application of New Type Matrix for Cell Sheet Engineering Use

  Tseng, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Systems engineering 100%
  • Cell culture 86%
  • Membranes 84%
  • Monomers 79%
  • Tissue 57%

• Surface Adsorption of Nanomaterials in Applications for Gas Sensor and Catalyst

  Lin, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Catalysts 100%
  • Zinc oxide 58%
  • Precious metals 58%
  • Cerium oxide 56%
  • Chemical sensors 50%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Shen, S., Yang, W., Li, Y., Yeh, C. & Kao, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• Fabrication of Plla Microtube Array (Mta) via Electrospinning --- the Array Formation of Poly-L-Lactic Acid/ Polyethylene Glycol, (Plla/Peg) Micro Shell /Core Fibers

  Chen, C. & Shen, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibers 100%
  • fabrication 46%
  • hollow 46%
  • flow velocity 40%
  • membranes 37%

• Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

  Yang, Y. & Leu, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphopyruvate Hydratase 100%
  • Anti-Idiotypic Antibodies 22%
  • Antibodies 17%
  • Single-Chain Antibodies 13%
  • Neoplasms 10%

• Development of the Balance Tele-Rehabilitation System with Virtual Reality and Functional Electrical Stimulation

  Chen, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Patient rehabilitation 100%
  • Virtual reality 54%
  • Accelerometers 25%
  • Feedback 16%
  • Information science 12%

• The Effect of Proteoglycans on Neurite Outgrowth and Functional Recovery in an Animnal Model with Spinal Cored Injury

  Yang, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neuronal Outgrowth 100%
  • Annexin A6 82%
  • perlecan 72%
  • chondroitin sulfate glycosaminoglycan 63%
  • Chondroitin Sulfate Proteoglycans 53%

• The Clinical Study of Hydrophilic Electrospun (ES) Pla/Bioceramic Guided Tissue/Bone Regeneration (GTR/GBR) Membranes

  Lee, S. & Yang, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Guided Tissue Regeneration 100%
  • Periodontal Index 42%
  • Periodontal Diseases 36%
  • Membranes 30%
  • Tooth 24%

• Mechanisms and Clinical Applications of Transcranial Direct Current Stimulation in Treating Patients with Firbomyalgia

  Kang, J., Chen, S. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 57%
  • Serotonin and Noradrenaline Reuptake Inhibitors 11%
  • Hyperalgesia 8%
  • Hydrotherapy 6%

• The Influences and Underlying Mechanisms of Differentiation and Proliferation in Ox-Ldl and Hdl-Stimulated Human Late-Outgrowth Endothelial Progenitor Cells.

  Huang, C., Lin, F., Lin, F. & Shyu, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endothelial Progenitor Cells 100%
  • erucylphosphocholine 98%
  • Endothelium 28%
  • HDL Lipoproteins 25%
  • Dyslipidemias 23%

• Application of Functional Electrical Stimulation on the Study of Nerve Regeneration in the Rat with Diabetic Neuropathy

  Peng, C. & Chen, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electric Stimulation 100%
  • Nerve Regeneration 94%
  • Urinary Tract 93%
  • Diabetes Mellitus 49%
  • Nerve Fibers 45%

• Gene Polymorphism of Fatty Acids Metabolism Enzymes in Elderly Patients with Depression and Mild Cognitive Impairment

  Huang, S. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Elderly 82%
  • Depression 79%
  • Apolipoprotein E2 61%
  • Fatty Acids 52%

• Integration of Research on Novel Antibacterial Mini-Implant

  Lin, C. & Ou, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • steel 100%
  • infection 96%
  • breakage 73%
  • titanium 67%
  • bacterium 65%

• Preparation and Modification of Tungsten Oxide Nanomaterials and Its Application as Gas Sensors

  Lin, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tungsten oxides 100%
  • gases 53%
  • catalysts 36%
  • preparation 28%
  • sensors 23%

• Study on Oseto Tissue Regeneration of Bio-Medical Material Scaffolds Using Anodic Aluminum Oxide with Curved Surface Combined Micro/Nanostructure

  Shen, Y.

  8/1/11 → 10/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Plastic products 100%
  • Femtosecond lasers 30%
  • Animals 28%
  • Nanostructures 23%
  • Transmission electron microscopy 20%

• Macro and Micro Biomechanical Studies of Soft Tissue Remodeling under Tissue Expansion

  Chen, H.

  8/1/11 → 11/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tissues 100%
  • skin (animal) 31%
  • mechanical properties 29%
  • animal injuries 22%
  • clinical trials 21%

• 影響各層級醫療院所口腔癌篩檢陽性個案接受後續確診之因素

  Huang, M.

  12/27/11 → 12/26/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Mouth Neoplasms 100%
  • Early Detection of Cancer 54%
  • Administrative Personnel 11%
  • Health Policy 11%
  • Referral and Consultation 8%

• 以奈米滾壓成形製作生醫塑膠奈米結構應用於動物實驗及其製程最佳化之研究

  Shen, Y.

  1/1/12 → 12/31/12

  Project: C - Project of Alliance › j - National Taipei University of Technology

• 含碘-鉑之奈米載體做為肺癌診斷之治療試藥之開發

  Tseng, C.

  1/1/12 → 12/31/12

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 供上肢復健訓練之數位滑板系統研製

  Chen, S.

  1/1/12 → 12/31/12

  Project: C - Project of Alliance › j - National Taipei University of Technology

• 大腸癌病人其抑癌基因甲基化與甲基轉移酵素變異的情形之分析

  Lin, R.

  1/1/12 → 12/31/12

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Preparation and Characterization of Novel ZnO/PLLA Nanocomposite of Nanowire-in-Microtube Array (NWiMTA)

  Chen, C.

  1/1/12 → 12/31/12

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Regulation of human β-defensin 3 expression in human intestinal epithelium by Salmonella enterica serovar Typhimurium

  Fang, S.

  1/1/12 → 12/31/12

  Project: C - Project of Alliance › j - National Taipei University of Technology