Taipei Medical University

Projects

Projects per year 2002 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 589 Active
• 7312 Finished

Projects per year

Search results

• Effects of Curcumin and Its 25 Kinds of Structural Analogs on Antiproliferation, Antimetastasis, Solubility Improvements, and Related Mechanism Investigations

  Hou, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Curcumin 100%
  • Antimetastatic 16%
  • Cell Viability 10%
  • Intraperitoneal 6%
  • Blood Pressure 6%

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs( I )

  Wang, J.

  8/1/12 → 7/31/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Traumatic Brain Injury 100%
  • Research Personnel 51%
  • Pharmaceutical Preparations 22%
  • Touch 18%
  • MicroRNAs 15%

• Cytotoxicity and Application on Drug Resistant Cells of Halide Derivatives of Rutaecarpine

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Evodiamine 100%
  • Poison 67%
  • Halide 66%
  • Topoisomerase Inhibitor 49%
  • Antimicrobial Agent 40%

• Investigation of the Transcriptional and Epigenetic Mechanisms for the Nm23-H1 Expression: an Nm23-H1-Promoter Screening Platform for Novel Metastasis-Suppressing Anticancer Drugs

  Wang, L.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasm Metastasis 100%
  • Genetic Promoter Regions 93%
  • Methylation 87%
  • Esophageal Neoplasms 66%
  • Tumor Suppressor Genes 63%

• Molecular Therpary and Mechanism Study in Spinal Cord Injury

  Hung, K.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 100%
  • 3-(1-benzenesulfonyl-1H-indol-5-yl)-N-hydroxyacrylamide 97%
  • Spinal Cord Injuries 31%
  • Chromatin 25%
  • Histone Deacetylase Inhibitors 16%

• Huntingtin-Associated Protein Related Biomarkers in Neural Survival

  Lin, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Huntingtin Protein 100%
  • Mouse Hap1 protein 77%
  • Microtubules 50%
  • Biomarkers 33%
  • Proteins 25%

• Effect of Pacemaker Current Inhibitor (Ivabradine) on Sinoatrial Node Function and Pulmonary Vein Arrhythmogenesis

  Lin, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Veins 100%
  • Ivabradine 66%
  • Atrial Fibrillation 48%
  • Sinoatrial Node 40%
  • Cardiac Arrhythmias 27%

• Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

  Wu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Breast Neoplasms 19%
  • Neoplasms 7%
  • Carcinogenesis 6%

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries

  Chen, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Effects of Glutamine Supplementation on T Cell Homeostasis and Inflammatory Response in Inflammatory Bowel Disease

  Yeh, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glutamine 100%
  • inflammatory bowel disease 84%
  • colitis 78%
  • T-lymphocytes 59%
  • ulcerative colitis 57%

• Genetic Polymorphisms of Calcium Channel in the Risk of Breast Cancer

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium Channels 63%
  • Breast Neoplasms 60%
  • Genetic Polymorphisms 37%
  • Calcium 24%
  • Case-Control Studies 18%

• Characterizationof Platelet-Rich Fibrin Releasing Growth Factors and Its Application on Regeneration of Nerve Injury during Radical Prostatectomy

  Ho, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibrin 100%
  • prostatic neoplasms 58%
  • nerve regeneration 51%
  • growth factors 40%
  • adhesives 38%

• Effects of Fish Oil on Alcoholic Liver Disease in Rats Based on Pathological Mechanisms

  Yang, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • liver diseases 100%
  • alcohol abuse 83%
  • fish oils 81%
  • liver function 46%
  • rats 39%

• The Pre-Clinical Assessment of the Anti-Tumor Efficacy of a Protein Vaccine and Mesenchymal Stem Cell Combined Therapy, Using Non-Invasive Molecular Imaging Technology

  Wu, A. T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vaccines 100%
  • Molecular Imaging 78%
  • Neoplasms 75%
  • Suicide 61%
  • Mesenchymal Stem Cells 59%

• The First Randomized Controlled Clinical Trial for Computerized Decision Support System (II)

  Li, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Contrast Media 100%
  • Drug-Related Side Effects and Adverse Reactions 60%
  • Clinical Decision Support Systems 56%
  • Physicians 54%
  • Randomized Controlled Trials 43%

• Molecular Mechanisms of Alpha 9-Nicotinic Acetylcholine Receptor (Alpha 9-Nachr)-Mediated Trastuzumab (Herceptinr) Drug Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • MicroRNAs 66%
  • Trastuzumab 62%
  • CP 14 54%
  • Antineoplastic Agents 50%

• The Pathogenic Role of Posttranslational Modification of Plasma N-Linked Glycoprotein to Rheumatoid Arthritis Combined Sjogren$S Syndrome Was Investigated

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sjogren's Syndrome 100%
  • Rheumatoid Arthritis 73%
  • Post Translational Protein Processing 62%
  • Blood Proteins 19%
  • Proteins 14%

• The Role of Microrna Let-7g in Cytosolic Ca2+ Regulation and Cox-2 Gene Expression

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Atherosclerosis 57%
  • Calcium Channels 51%
  • Gene Expression 42%
  • Epigenomics 41%

• The Roles of Fibronectin Fragments in the Articular Chondrocytes: from Single Nucleotide Polymorphism to Functional Investigation.

  Lee, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • chondrocytes 59%
  • cartilage 53%
  • integrins 43%
  • osteoarthritis 23%

• The Exploitation of Taiwan Native Plants in Promoting Bone Growth and Establishment of the System Biology Platform

  Lee, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Uraria crinita 100%
  • osteoblasts 67%
  • Taiwan 65%
  • bones 48%
  • Biological Sciences 27%

• 睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生，形成症狀群集，影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨，然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解，仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗，將有助於未來睡眠評估工具之修訂。另外， 在評估癌症病人睡眠品質時，若能以簡單工具評估，會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷，廣為使用在一般失眠的病人， 在癌症病人使用上，尚未有豐富的實證資料，若能建立其在癌症病人的信效度，將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則，日夜節律又需要光作為矯正的線索，光在癌症病人睡眠的 角色，尚未有研究證實，過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索，光療法透過褪黑激素調節，調整日夜節律週期，可能可以改善睡 眠品質。另外，由於，睡眠障礙、憂鬱、疲憊經常形成一症狀群集，光療法於改善睡眠 障礙之同時，是否亦同時改善憂鬱、疲憊及生活品質。目前，光療法在癌症病人的運用 上，付之闕如，故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫，目的包括有：1.瞭解癌症個案對於睡眠困擾的主觀經驗 （第一年）。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性（第一年）。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係（第二年）。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效；以及瞭解光療法影響褪黑激素之 程度（第三年）。 本研究擬以癌症住院及門診病人為對象，研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷，簡明疲憊量表，貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括：內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係，並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效，以期，最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Phototherapy 34%
  • Neoplasms 25%
  • Sleep Initiation and Maintenance Disorders 22%
  • Light 15%

• Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipocytes 100%
  • Atrial Fibrillation 64%
  • Cardiac Myocytes 60%
  • Calcium 44%
  • Adipokines 37%

• Studies of Molecular and Cellular Underlying Mechanisms of Ferrous Citrate-Induced Cerebral Vasospasm and Brain Injury

  Lee, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Subarachnoid Hemorrhage 100%
  • monoferrous acid citrate 89%
  • Intracranial Vasospasm 74%
  • Brain Injuries 53%
  • Thioredoxins 49%

• Endothelin-1 Mediates Fibrocyte Differentiation in Chronic Obstructive Asthma

  Lin, C.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Asthma 100%
  • Fibrosis 76%
  • Myofibroblasts 73%
  • Lung 61%
  • Connective Tissue Growth Factor 51%

• 探討加護病房多種致病微生物揮發性有機成分

  Shih, C.

  7/25/12 → 11/30/12

  Project: A - Government Institution › f - Other (Funded by Government)

• The studies and analysis of the addiction,abuse and social risk of emerging abused drugs

  Sheu, S.

  7/10/12 → 12/31/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Pharmacopoeias 100%
  • Names 98%
  • Pharmaceutical Preparations 75%
  • Pharmaceutical Databases 73%
  • 2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one 63%

• 護理碩士進階實務人才培育共識論壇

  Lin, C.

  7/6/12 → 7/27/12

  Project: A - Government Institution › d - Ministry of Education

• 以混合羅吉特模型分析機車路口使用兩段式左轉之行為

  Pai, C.

  7/5/12 → 9/3/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• 101年度建置健保法學知識數位平台

  Yang, C.

  6/29/12 → 12/28/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • health insurance 100%
  • electronic learning 24%
  • death and dying 12%
  • needs assessment 10%
  • health care workers 8%

• Study of solid cultivated fruit bodies of Antrodia camphorata combined with or without aspirin on neuroprotection and lowering the neurobehavioral deficits in rat ischemic stroke: evaluating the risks of inducing hemorrhagic side effects.

  Sheu, J.

  6/1/12 → 12/31/12

  Project: A - Government Institution › e - Council of Agriculture

  • Antrodia 100%
  • Stroke 44%
  • Aspirin 29%
  • Cardiovascular Diseases 18%
  • Dietary Supplements 13%

• Research Symposium for Chinese Medicine Research Projects

  Liang, W., Huang, W. & Lin, M.

  6/1/12 → 12/15/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • medicine 100%
  • research results 51%
  • academic exchange 41%
  • poster 29%
  • budget 22%

• Feasibility of Capitation for the Accountable Family Physician System: An Exploratory Study

  Sheu, M., Hsu, Y. & Wen, H.

  5/2/12 → 3/31/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • health insurance 100%
  • family physician 61%
  • stakeholder 22%
  • fee-for-service 21%
  • Health Care Providers 17%

• 計劃時程生產與自然時程生產之醫療費用分析

  Sheu, M.

  5/1/12 → 7/31/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 以前瞻性乳房專用MRI追蹤方式，觀察婦女服用女性動情激素荷爾蒙或非藥物性食品/補充品((包含植物性（主要是動情激素）)，比較停藥前後和使用藥物前後對乳房MRI影像的影響

  Leung, T.

  5/1/12 → 12/31/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 子宮病變與環境荷爾蒙之關係研究

  Lee, C.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 淋巴管內皮細胞粒腺體導致細胞死亡的關鍵角色探討

  Sheu, J.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• α2A-Adrenergic receptor在加護病房新興鎮靜藥物dexmedetomidine誘發神經保護作用過程中所扮演的角色研究

  Wu, G.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 第四型類鐸接受器在大腸直腸癌化學治療效果上的角色及其作用機制探討

  Huang, M.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 神經細胞中過氧化物?體增殖物活化受體-γ在高血糖及缺氧環境下的表現及對神經細胞存活能力的研究

  Chi, N.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 環境荷爾蒙與多囊性卵巢婦女生殖荷爾蒙之相關性

  Hsu, M.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討眼窩脂肪幹細胞對巨噬細胞活性之影響及其相關調控機制

  Ho, J.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 薑黃素衍生物的抗癌癌細胞轉移活性研究

  Hou, W.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討以植物化學成分抑制β-catenin/PIN1訊息傳道路徑於肝癌幹細胞的發生

  Wu, A. T.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 薑黃素衍生物的抗發炎活性分析與機制探討

  Liang, Y.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• (101NP1003) New Drug Development of MPT0E014 for Ischemic Stroke and Dementia (I)

  Hung, K.

  5/1/12 → 4/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 3-(1-benzenesulfonyl-1H-indol-5-yl)-N-hydroxyacrylamide 100%
  • Stroke 25%
  • Dementia 20%
  • Chromatin 13%
  • Acetylation 9%

• 來自冬蟲夏草菌絲體及靈芝之多醣體萃取物對於炎症淋巴水腫的影響

  Lin, C.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 低能量雷射對老鼠胚胎幹細胞衍生之肌肉幹細胞之影響

  Chang, H.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 跑步機運動對巴金森氏病患者步態、認知功能、運動功能及生活品質之改善成效

  Yuan, R.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Hesperidin-3’-O-methylether在天竺鼠組織抑制3H-rolipram於high-affinity rolipram binding sites之結合及phosphodiesterase isozymes 1~5之活性

  Ko, W.

  5/1/12 → 4/30/13

  Project: C - Project of Alliance › p - Taipei Medical University Hospital