Taipei Medical University

Projects

Projects per year 2002 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 589 Active
• 7312 Finished

Projects per year

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• 探討黃腐醇合併降血糖藥是否可調控粒線體失常並經由活化未摺疊蛋白反應所激發之AMPK-NRf2-ARE-Glo1路徑來逆轉雙羰基壓力導致之糖尿病腎脂毒性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用轉錄體學與蛋白質體學方法探討膀胱癌對鉑類藥物產生抗藥性之分子機轉研究並開發新的治療策略(第二年)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bicalutamide經Sirt3/p53引發腎膈細胞電子傳遞鏈複合體I缺陷而致細胞凋亡機制的探討-輔以Idebenone及MitoTempo提升氧化磷酸化系統及調節粒線體動態之治療策略評估

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 穴位按壓介入對具有認知功能障礙的長照機構長者之認知功能和生活品質之成效: 叢聚隨機控制試驗(2/2)

  Chen, I.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 突觸支架蛋白Shank3調控神經發炎反應在急性缺血性腦中風之病理作用機制研究(2/2)

  Hsieh, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 3D實境對於達文西手術教學平台建立與操作能力提升(2/2)

  Liu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Tactile Massage in Improving Older Residents' Loneliness, Anxiety, and Depression in Long-Term Care Facilities

  Chuang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討孩童肥胖，青春期發育與胰島素阻抗之基因生活型態影響因素(3/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立傳染疾病的全球傳播風險預警架構：評估台灣與東亞區域的境外移入風險(2/2)

  Chuang, T.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 潛在臨終個案篩檢計分系統：應用死亡風險預測與機器學習於心臟衰竭與慢性腎臟衰竭患者之安寧療護需求評估

  Chang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma( III )

  Wu, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 滑世代幼兒期親子睡眠與晝夜節律追蹤研究-整合智慧型資料探討3C產品使用與孕產期相關因子影響效應(2/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 活性維生素D經由非典型高等糖化終產物受體與纖維母細胞生長因子受體訊息調控心臟纖維母細胞與糖尿病心臟纖維化之關聯(3/3)

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探究LINC01540/miR-107調控軸於口腔癌惡化進程之功能及其臨床意涵

  Tsai, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建置公衛研究專用之衛星遙測影像環境資料自動化平台

  Chuang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以尿苷雙磷酸葡萄糖醛酸基轉移酶2B7 (UGT2B7) 開發新穎三陰性乳癌標靶治療策略(1/3)

  Lee, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Integrated Study of Clinical, Molecular Analysis, Mr-Based Radiogenomic, and Preclinical Trials for Precision Treatment of Atypical Teratoid/Rhabdoid Tumor (Atrt) in Children(2/3)

  Wong, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Atypical Teratoid Tumor 99%
  • Tumor Cell Line 18%
  • Drug Therapy 15%
  • Neoplasms 14%
  • Radiotherapy 12%

• 利用次世代定序研究細菌與黴菌菌相與黴菌性鼻竇炎的關聯(1/3)

  Chang, T.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Benefical Effects and Mechanisms of Probiotics and Exercise Intervention Strategies in 6-Ohda Induced Parkinson'S Disease Rat(1/3)

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Probiotics 100%
  • Oxidopamine 81%
  • Parkinson Disease 39%
  • Substantia Nigra 25%
  • Gastrointestinal Microbiome 23%

• 探討真菌衍生之抗神經發炎成分及其對視網膜疾病之療效評估(3/3)

  Hsiao, G.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 母親食安風險認知對孩童體內實際鉛、鎘、砷暴露之影響(1/3)

  Chien, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建置與評估可擴充式機器學習演算法之重症醫療資訊平台

  Lo, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 非洲史瓦帝尼王國引致癲癇之神經性犬蛔蟲症或神經性囊尾幼蟲症之分子流行病學、相關危險因子與蟲體親緣分析(2020-2023)

  Fan, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 免疫圖譜與免疫球蛋白及其醣化胜?質譜分析技術建立與臨床應用(3/3)

  Kao, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Omega-3脂肪酸合併褪黑激素致效劑改善憂鬱症狀與生物日夜週期機制之探討： 一項營養與精神醫學之轉譯研究(1/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation of Senior Driving Simulation Training on Executive Function, Cognitive Promotion and Eeg in Subjective Cognitive Decline and Mild Cognitive Impairment. (1/3)

  Chiu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發透明質酸基奈米藥物以增強後眼部藥物遞送效能及應用於藍光誘導損傷之視網膜病變治療

  Tseng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展干擾染色質複製時期基因體穩定性之藥劑 (第二至四年)

  Lee, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探索蝦急性肝胰腺壞死病毒素 PirAvp 與 PirBvp 之活化機制與中和策略(1/3)

  Wang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立類神經網路模型以評估手術病患發生呼吸中止與低血氧的風險

  Chang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內 T 細胞於腫瘤微環境抗癌功效之創新協同療法-發展新型聚乙二醇-免疫增敏奈米藥物載體以毒殺大腸癌並強化腫瘤區域T細胞之抗癌功效(1/3)

  Liu, D.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 將BTK-ITK途徑作為標靶以克服肺癌治療的抗藥性以及抑制腦轉移的策略(2/3)

  Kuo, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Aza-PBHA , 透過調控芳香烴受體於糖尿病視網膜病變治療潛力機制探討(1/3)

  Cheng, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用結構生物學與蛋白質體學探討植物菌質體 PHYL1 交互作用蛋白質

  Wang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(1/3)

  Chuang, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 腦創傷老人中長期多重功能變化以及整體功能評估工具在輕度腦創傷老人之檢驗(1/3)

  Lin, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用機器學習演算法透過基因體資訊挖掘未知基因的功能與預測細菌抗藥性(2/3)

  Wu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 為腎臟替代療法患者建立永續發展的營養照護生態系統

  Yang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對C型肝炎引發之肝細胞癌開發之溶瘤麻疹病毒精準醫療(3/3)

  Lin, L. T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發高效能人工光合作用系統(1/2)

  Kuo, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Lycium Barbarum Polysaccharides and Capsaicin on the Healing of Ulcerative Colitis-Mechanisms of Antioxidation, Anti-Inflammation, Anti-Apoptosis, Analgesic Activity, Intestinal Permeability, Cytoprotection, and Microbiota Regulation(2/3)

  Chao, J. C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-對免疫療法併用方案節拍式化療或射頻燒灼療法之胰臟癌患者進行基因標記和免疫基因組庫之鑑定與分析(2/3)

  Chang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Trajectory of Psychological Distress among Infertility Women: Efficacy and Mechanism of Mind-Body Intervention with Heart Rate Variability Biofeedback (3/3)

  Kuo, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 精準健康科學之應用隨機模型-生物資訊隨機過程於精準健康科學之應用(2/3)

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制NLRP3發炎體- 糖尿病心肌病變的治療新策略

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:動物模式與人類世代之整合研究-青少年期慢性睡眠剝奪對認知、情緒與壓力調適功能之影響:健康青少年族群之觀察追蹤與介入研究(2/3)

  Lee, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以電混凝浮除法同時處理火力發電廠廢水中硼與硝酸鹽之研究(1/3)

  Hu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Choroid Plexus as a Hub of Immune-Clock Interaction That Connects the Body to the Brain in Prematurity (1/3)

  Myung, J.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 治療膠質母細胞瘤之新穎小分子多標靶抗癌藥物之設計合成與開發

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology