Projects per year
- 7,000 - 7,050 out of 8,639 results
Search results
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Investigation of the Transcriptional and Epigenetic Mechanisms for the Nm23-H1 Expression---An Nm23-H1-Promoter Screening Platform for Novel Metastasis-Suppressing Anticancer Drugs
Wang, L.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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https://www.grb.gov.tw/search/planDetail?id=8356932&docId=447412
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Evaluate the Molecluar Mechanims and Clinical Application on Atf3 Regulated microRNAs
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Exploitation of Taiwan Native Plants in Promoting Bone Growth and Establishment of the System Biology Platform
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effect of Vasopressin Receptor Agonist and Antagonist on Pulmonary Vein and Atrial Arrhythmogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Effects of the APOE4 Allele on Cerebral Structural and Functional Connectivity---A Diffusion Tensor Imaging and Resting-State MRI Study
Chen, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Arsenic Methylation Capacity, Methylenetetrahydrofolate Reductase and Dna Methylation Gene Polymorphisms, Plasma Selenium Concentration and Selenoprotein Gene Polymorphisms and Renal Cell Carcinoma
Hsueh, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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周產期尼古丁及新生兒高氧暴露對仔鼠心臟及腎臟的影響
3/1/14 → 7/31/15
Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital
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The Study of the Relationships among Anti-Obesity Activity, Adipogenesis, and Adipose Angiogenesis of Vegetable Indolic Derivatives---Involvement of the Ah Receptor/Arnt ?(III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Identifying Prostate Cancer Biosignature from Multi-Scale Mixture-Lineage Modeling of Tumor Cell Progression
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Effects of Adipose-Derived Stem Cells on Denervated Rat Skeletal Muscle Atrophy
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Chemo-Sensitizer Conjugated Carbon Nanotubes as a Novel Cancer Therapeutical Delivery System
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma---The Treatment of Metastatic Cancer
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Investigation on Dental Implant Stability Detection Using Damping Factor as a Parameter
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Resveratol on Proliferation of Leiomyoma: in Vitro and in Vivo Study (A09)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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TMU102-AE1-B27
1/1/14 → 7/31/15
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty
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ALA Photodynamic Therapy, Tumor Hypoxia, CSE1L Phosphorylation, and the Progression and Treatment of Skin Cancer
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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To See Is to Believe-Visualization of the Spectrum on Chronic Kidney Disease
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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抗氧化防禦基因標籤單核?酸多形性、氧化壓力生物標記與冠狀動脈心臟病之相關性(2/2)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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鐵質誘發巨噬細胞活化與遷移對胰島素耐受性的影響
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effects and Mechanisms of Massotherapy of Acupoints, Gene Polymorphisms of RRM1 and RRM2 on Relieving Chemotherapy-Induced Myelossupression among Patients with Cervical Cancer
8/1/13 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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TMU102-AE1-B45
7/1/14 → 7/31/15
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty
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The Process Development of Electrospun Silk Fibroin/Sacchachitosan Membranes for Endotoxin Removal Applications
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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腫瘤相關巨噬細胞在誘發產生表皮生長因子受器酪胺酸酉每抑制劑的抗藥性的角色
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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To Investigate the Role of SPNS2 in Determining Individual Susceptibility to Hypoxic Challenge
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Spatiotemporal Analysis of the Effects of Ambient Bioparticles on Allergic Diseases in the Greater Taipei Area
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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老年性聽力損失: Cisd2缺失會加速老化過程中的聽力損傷
11/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Design and Characterization of Multifunctional Self-Assembling Lecithin/Amphiphilic Polymers Mixed Micellar Delivery Systems
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Therapeutic Implications of Down-Regulation of Microglia Activation Following Repetitive Traumatic Brain Injury-Induced Chronic Traumatic Encephalopathy
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)
Huang, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Role of CISD2 in the Female Reproductive System of Mammal
Chang, H.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Genetic Polymorphisms in microRNA and Risk of the Post-Thrombolytic Hyperglycemia in Acute Ischemic Stroke and Its Prognosis Study
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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肺纖維化之轉譯研究－組蛋白去乙醯酉每2的SUMO化修飾貢獻於慢性阻塞性氣喘的結締組織生長因子表現與肺部纖維化反應(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Role of Organic Anion Transporter in Renal Tubular Injury---A Gateway to Hurt
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Drug Discovery and Pharmacological Study of Novel pan-HDAC Inhibitors as Anti-Angiogenic Drugs
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Role of CCR5/RANTES in Neurodegeneration
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色：經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成酉每)的調控與白蘆黎醇/史達汀臨床治療及應用(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Investigation of the Oncogenic Role of Prohibitin in Breast Cancer Progression
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Exploration of RBM4-Regulated Splicing Events in Differentiating Adipocytes by Using Next-Generation Sequencing
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Effect of Health Risk Behaviors on Recurrent Traffic Injury
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Investigating of Transcranial Direct Current Stimulation and Robot-Assisted Gait Training Effects in Subjects with Stroke (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Evaluate the Radio-Biological Roles of miR-17-5P in Oral Cancer Cell Line OC3
Wu, S.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Novel Roles of Aldose Reductase (AR) in Collagen GPVI- and Thrombin PAR4-Mediated Platelet Activation and Apoptosis---Regulatory Machinery of Arf-AR Signaling in Anucleate Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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核糖核甘酸還原酉每抑制劑在人類乳突瘤病毒感染之非小細胞肺癌治療效果評估
Hsu, N.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council