School of Respiratory Therapy

Projects

Projects per year 2010 2019 2020 2021 2022 2023 2027

• 8 Active
• 195 Finished

Projects per year

Search results

• Active

  Investigating the Role and Mechanism of Usp24 on Pulmonary Fibrosis

  Wang, S.-A. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• To Explore the Mechanism of Pp4 in Macrophage Pyroptosis during Sepsis

  Yang, F.-M. (PI)

  8/1/24 → 7/31/27

  Project: A - Government Institution › b - National Science and Technology Council

• Role of Senp1 in Regulating Sumoylation of Pp4c and Lung Fibrosis in Idiopathic Pulmonary Fibrosis

  Wu, Y.-C. (PI)

  8/1/24 → 7/31/27

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of the Pathological Function of Lemur Tyrosine Kinase 3 (Lmtk3) in Thrombin-Induced Il-8/Cxcl8 Expression and Airway Inflammation in Type-2-Low Severe Asthma

  Chen, B.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 探討缺氧環境對胚胎肺臟形態學發育的機轉

  Chuang, H.-C. (PI)

  1/1/24 → 12/31/24

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 探討蛋白質去磷酸酶PP4於敗血症中調控嗜中性細胞胞外誘捕網的機制

  Yang, F.-M. (PI)

  1/1/24 → 12/31/24

  Project: A - Government Institution › a - National Health Research Institutes

• The Role of Fndc5/Irisin through Regulation of Mitochondrial Function in Airway Subepithelial Fibrosis of Severe Asthma

  Cheng, W.-H. (PI)

  1/1/24 → 12/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Cheng, W.-H. (PI)

  11/1/23 → 10/31/24

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Finished

  探討在慢性阻塞性肺病由PM2.5造成肺氣腫的潛在ITIH缺失之分子機轉型 －探討PM2.5的金屬成分對慢性阻塞性肺病之ITIH表現研究：鐵依賴型細胞死亡所扮演的角色(2/3)

  Chuang, H.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 結合穿戴與臨床大數據建構睡眠呼吸健康照護模式(1/3)

  Liu, W.-T. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 肺部纖維化的新穎治療策略：關閉肌成纖維細胞活性同時啟動免疫監控機轉(2/3)

  Chen, C.-L. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• TSLP/IL-7Ralpha在嚴重T2氣喘中調控上皮屏障崩壞之角色探討(1/3)

  Weng, C.-M. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Omeprazole (Prilosec®) 引發呼吸道過度敏感之機制探討(2/3)

  Hsu, C.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 氣候敏感性對慢性阻塞性肺病之疾病韌性研究(1/3)

  Chuang, H.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討serine/threonine kinase 33 (STK33)於嚴重氣喘中thrombin誘導趨化因子IL-8/CXCL8表現及氣道發炎之病理角色

  Chen, B.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Doublecortin like kinase protein 1 (DCLK1)在支氣管肺纖維化中的病理生理學研究－ADAM17/ACE2調控DCLK1過度的表現參與呼吸道纖維化角色探討(2/3)

  Chen, B.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• TRIM5調控肋膜間皮細胞的間皮間質轉形和細胞遷移於特發性肺纖維化的影響機轉

  Chung, C.-L. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研究基質金屬蛋白酶-28對慢性阻塞性肺疾病合併肺氣腫患者發炎反應和疾病進展的調節作用(2/3)

  Ho, S.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研究慢性阻塞性肺病中調控發炎老化的新機轉: miR-1, miR-133及let-7c之負調控導致過度活化gp130-IL-6信號傳遞路徑(3/3)

  Su, B.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討USP24抑制劑的鐵依賴性死亡機制並作為癌症抗藥性與纖維化的潛力治療策略

  Wang, S.-A. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討在慢性阻塞性肺病由PM2.5造成肺氣腫的潛在ITIH缺失之分子機轉型 －暴露於 PM2.5 的 COPD 患者中 ITIH 介導的嗜中性白血球調節之研究：先天免疫和適應性免疫之間的聯繫(2/3)

  Ho, S.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Doublecortin like kinase 1 (DCLK1)在支氣管肺纖維化中的病理生理角色－探討DCLK1調節上皮細胞間質轉化誘發第二型免疫反應在嚴重氣喘疾病中的角色(2/3)

  Chen, C.-L. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 呼吸道微生物體對慢性阻塞性肺病之穩定性及皮質類固醇對其療效之相關性研究

  Chang, J.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討去磷酸酶PP4在柴油排放粒子誘導嚴重過敏性發炎反應中的角色(3/3)

  Yang, F.-M. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討Pref-1在人類肺部纖維母細胞中誘導DCLK1表現的機制

  Chen, B.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討ITIH4對急性呼吸窘迫症候群之治療研究：LARS2在第二型肺泡上皮細胞分化之角色

  Chuang, H.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 新冠肺炎病毒3CL蛋白酶透過切斷IRAK- 1以抑制干擾素抗病毒機轉之研究

  Su, B.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討USP24抑制劑的鐵依賴性死亡機制並作為肝纖維化的潛力治療策略

  Wang, S.-A. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討SENP1/PP4C因子與特發性肺纖維化 、閉塞性細支氣管炎、慢性阻塞性肺病之關聯性

  Wu, Y.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 吳茱萸次鹼對抑制大腦血管內皮細胞發炎以及血管平滑肌細胞增生的機轉探討及效價評估

  Chung, C.-L. (PI)

  3/1/23 → 2/29/24

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 探討DCLK1/IL-23在漸進纖維化間質性肺病之病理角色

  Chen, B.-C. (PI)

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 慢性阻塞性肺疾病面對極端氣象事件與氣候變遷下溫度變化對於疾病嚴重度之轉譯研究

  Chuang, H.-C. (PI)

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 非侵入式呼吸器品質驗證方法評估

  Chuang, H.-C. (PI)

  1/1/23 → 12/31/23

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Study on the Pathological Role of Dclk1 in Thrombin-Induced Il-8/Cxcl8 Expression and Airway Inflammation in Chronic Obstructive Asthma

  Chen, B.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation into Metal Effects of Pm2.5 on Itih Expression in Copd: the Role of Ferroptosis( I )

  Chuang, H.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Study on Dclk1-Mediated Epithelial-Mesenchymal Transition Conducing to Type 2-Biased Immune Responses in Severe Asthma( I )

  Chen, C.-L. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of Itih-Mediated Neutrophil Modulation in Copd Patients Exposed to Pm2.5: Link between Innate and Adaptive Immunity( I )

  Ho, S.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Effects of Glyoxalase 1 Gene Manipulation on Metabolic Stress-Mediated Lung Cancer Cell Epithelial-Mesenchymal Transition and Metastasis in Malignant Pleural Effusion

  Chung, C.-L. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Exploring the Role of Protein Phosphatase 4 in Dep-Exacerbated Allergic Inflammation (2/3)

  Yang, F.-M. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Upregulated Fceri Trigger Epithelium Instability and Imbalance of Epithelium Immune Microenvironment in Severe Allergic Asthma

  Weng, C.-M. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• To Investigate the Role of Usp24 between Lung Cancer and Copd

  Wang, S.-A. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Study on the Role of Adam17/Ace2 in Doublecortin Like Kinase 1 (Dclk1) Overexpression Responsible for Airway Fibrosis( I )

  Chen, B.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Novel Therapeutic Strategy against Pulmonary Fibrosis: Switching off Myofibroblast Activities While Arousing the Effective Immune Surveillance (1/3)

  Chen, C.-L. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Mechanisms Underlying the Airway Hypersensitivity Induced by Omeprazole (Prilosec®)

  Hsu, C.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation into the Effects of Metal Fine Particulate Matter on Yap/Taz-Regulated Cellular Senescence in Alveolar Epithelial Type II Cells of Chronic Obstructive Pulmonary Disease

  Chuang, H.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Down-Regulation of Mir-1, Mir-133a, and Let-7c Reduces to Control Gp130-Il-6 Signaling, a Novel Role to Promote Inflammaging in Copd (2/3)

  Su, B.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• To Study the Regulation of Mmp-28 on the Inflammatory Response and Disease Progression of Copd Patients with Emphysema (1/3)

  Ho, S.-C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 脂多醣對於YAP/TAZ調控胚胎肺部發育的纖維母細胞衰老與小兒支氣管肺發育不全關聯性之研究

  Chuang, H.-C. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• ADAM17/CX3CL1在TGF-ꞵ誘導的促纖維化蛋白及纖維母細胞的分化在嚴重氣喘病人的氣道纖維化

  Chen, B.-C. (PI)

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 暴露於PM2.5的COPD 患者基於嗜中性球胞外網狀結構的免疫病理學研究

  Ho, S.-C. (PI)

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project