School of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 201 Active
• 2325 Finished

Projects per year

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• b - Ministry of Science and Technology

  標靶B型肝炎誘發之肝癌腫瘤生成與Sorafenib抗藥性之微環境：聚焦發炎激素與癌幹細胞特性之轉譯精準醫學研究與臨床意義-探討微環境發炎細胞激素與基因後生調節於B型肝炎病毒誘導之肝癌表現多能性幹細胞基因OCT4與Sorafenib抗藥性之調控機制與其臨床意義(3/3)

  Huang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Niche Signaling Networks in Self-Renewal and Migration of Pluripotent Germline Stem Cells and Its Implication for Germline Differentiation in Human Pluripotent Stem Cells (III)

  Huang, Y.

  10/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of High Mobility Group Box-1 Protein in Human Vascular Smooth Muscle Progenitor Cells in Regard to the Occurrence of Allograft Vasculopathy after Heart Transplantation

  Lin, F.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • High Mobility Group Proteins 100%
  • Vascular Smooth Muscle 97%
  • Smooth Muscle Myocytes 87%
  • Heart Transplantation 62%
  • Allografts 60%

• 再生醫學科技發展計畫(4/4)－全身安全性異體移植策略之細胞治療產品開發：標靶醫療未滿足慢性發炎相關疾病—糖尿病/褥瘡/嚴重燒燙傷之傷口癒合與多發性硬化症

  Huang, Y.

  5/1/20 → 4/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• 探討新穎小分子化合物影響三陰性乳癌細胞免疫檢查點之機制

  Huang, S.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Immunomodulatory Role of Melatonin in Promoting the Progression of Graves' Disease

  Lin, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • melatonin 100%
  • thyrotropin receptors 35%
  • thyroid diseases 25%
  • hyperthyroidism 14%
  • autoimmune diseases 13%

• Niche Extracellular Matrix (Ecm) and Hypoxia Promote Symmetric Self-Renewal Proliferation and Migration in Embryonic Germline Stem Cells through Igf-1r-Hif-2a Central Signaling Pathway

  Au, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stem Cells 100%
  • Alkaline Phosphatase 88%
  • Cell Hypoxia 45%
  • Germ Cells 44%
  • Hypoxia 42%

• The Role and Mechanism of Cd155/Tigit in Mdsc/Tam Induced Nk Cell Dysfunction -A Link to Lung Cancer Resistance to Immune Checkpoint Blockade

  Feng, P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Human Leukocyte Antigen Polymorphisms Associated with the Efficacy of Hepatitis B Virus Vaccination

  Su, F.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatitis B virus 100%
  • HLA Antigens 83%
  • Hepatitis B Vaccines 75%
  • Hepatitis B Antibodies 49%
  • Vaccination 35%

• 新穎性結構天然物??衍生物於血管及淋巴管新生抑制與抗腫瘤之應用及其機轉探討(1/3)

  Huang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Hep G2 Cells 36%
  • Androgens 30%
  • Neoplasms 29%
  • sulfoenolpyruvate 21%

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Characterization of both carbapenem- and colistin-resistant Acinetobacter clinical isolates: mechanisms of antimicrobial resistance, virulence and fitness

  Huang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.(I)(1/3)

  Huang, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cell Sheet Engineering for Primary Corneal Endothelial Cells and Its Animal Model

  Tseng, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endothelial Cells 100%
  • Transplants 31%
  • Cornea 31%
  • Polyglutamic Acid 27%
  • polyvinylidene fluoride 26%

• Reflex Pelvic Floor Muscle Activities in Women with Urinary Incontinence (II)

  Yang, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • muscle contraction 100%
  • urinary incontinence 92%
  • reflexes 85%
  • muscles 36%
  • perineum 21%

• Metabolomic Analysis of Tuberculous Pleural Effusions with Residual Pleural Thickening

  Chung, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pleural Effusion 100%
  • Platelet Activating Factor 90%
  • Small Interfering RNA 21%
  • Epithelial-Mesenchymal Transition 19%
  • Metabolomics 13%

• Service for Sharing Precious Instruments of Taipei Medical University

  Lin, C.

  1/1/14 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effect of pacemaker current inhibitor (Ivabradine) on sinoatrial node function and pulmonary vein arrhythmogenesis

  Lin, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Veins 100%
  • Ivabradine 66%
  • Atrial Fibrillation 48%
  • Sinoatrial Node 40%
  • Cardiac Arrhythmias 27%

• 研究合併E1A基因和表皮生長因子受體酪氨酸激?抑制劑在三重陰性乳癌臨床前治療的嶄新策略(1/3)

  Su, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Preparation and Application of New Type Matrix for Cell Sheet Engineering Use

  Tseng, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Systems engineering 100%
  • Cell culture 86%
  • Membranes 84%
  • Monomers 79%
  • Tissue 57%

• Reflex Pelvic Floor Muscle Activities in Women with Urinary Incontinence (II)

  Yang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • muscle contraction 100%
  • urinary incontinence 92%
  • reflexes 85%
  • muscles 36%
  • perineum 21%

• 降解型細胞自噬藉由促進微小RNA miR-449a表現量抑制大腸直腸癌之進程進而發展治療大腸癌之新策略(2/2)

  Wu, S.

  6/1/21 → 5/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 重點產業高階人才培訓與就業計畫

  Lin, C.

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Implication of Plasminogen Activator Inhibitor-1 in the Regulation of Thrombin-Induced Fibrogenesis in Inflammatory Pleural Effusions.

  Chung, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Plasminogen Activator Inhibitor 1 100%
  • Thrombin 81%
  • Fibrosis 40%
  • Collagen 18%
  • Pleural Effusion 17%

• 110年度產業高階人才培訓計畫

  Lin, C.

  5/1/21 → 4/30/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Preparation and Application of New Type Matrix for Aligned Cell Sheet Engineering Use

  Tseng, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tissue 100%
  • Cell culture 65%
  • Membranes 56%
  • Engineering technology 40%
  • Cystines 33%

• Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs

  Hsieh, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Atrial Fibrillation 87%
  • Heat-Shock Proteins 68%
  • Indican 66%
  • Neomycin 41%

• Service for Sharing Precious Instruments of Taipei Medical University

  Lin, C.

  1/1/11 → 1/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs

  Hsieh, M., Chen, Y. & Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Atrial Fibrillation 87%
  • Heat-Shock Proteins 68%
  • Indican 66%
  • Neomycin 41%

• Decellularized Plant Extracellular Matrices as a Scaffold for Tissue Engineering

  Tseng, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • extracellular matrix 100%
  • animal tissues 65%
  • tissue engineering 44%
  • porometers 29%
  • polyglutamic acid 28%

• Effect of Pacemaker Current Inhibitor (Ivabradine) on Sinoatrial Node Function and Pulmonary Vein Arrhythmogenesis

  Lin, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Veins 100%
  • Ivabradine 66%
  • Atrial Fibrillation 48%
  • Sinoatrial Node 40%
  • Cardiac Arrhythmias 27%

• The Molecular Basis, Preventive Efficacy of Angiotension II Receptor Blockade and Quality of Life in Marfan Syndrome

  Chiu, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Marfan Syndrome 100%
  • Fibrillin-1 35%
  • Losartan 28%
  • Dilatation 19%
  • Quality of Life 15%

• Detrimental Effects of an Aryl-Hydrocarbon Receptor Agonist, 3mc, on Brain Vascular Integrity and Permeability, and the Therapeutic Intervention by Statin Derivatives.

  Juan, S. & Hwang, L.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Retinoblastoma Protein 56%
  • extracellular matrix receptor 50%
  • Extracellular Matrix Proteins 49%
  • Phosphatidylinositol 3-Kinases 33%

• Service for Sharing Precious Instruments of Taipei Medical University

  Lin, C.

  1/1/12 → 12/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Beta 3腎上腺素信號傳導對心律異常的發生：從心室心肌細胞中心臟代謝，氧化壓力和鈣離子恆定的見解

  Hsieh, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Telekaryophagy, an Novel Entire Nucleus Elimination Programme in the Liver and Mammary Gland: Exploring Its Role in Genomic Stability and Physiopathology

  Chao, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Big Data Analytics to Build Risk Assessment Models of Postoperative Complications for Patients with Chronic Pulmonary Disease

  Lin, C.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Postoperative Complications 100%
  • National Health Programs 81%
  • Risk Assessment 64%
  • Big Data 52%
  • Support Vector Machine 47%

• Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats

  Peng, C.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Deep Brain Stimulation 100%
  • Traumatic Brain Injury 76%
  • Brain 29%
  • Urinary Bladder 27%
  • Urination 19%

• Big Data Analysis to Build Risk Assessment Models for Perioperative Major Cardiac Complications in Patients with Diabetes, Hypertension, or Stroke

  Lin, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • National Health Programs 100%
  • Databases 95%
  • Big Data 86%
  • Risk Assessment 79%
  • Data Mining 76%

• The Role and Mechanisms of Metabolomics in the Outcome of Acute Ischemic Stroke

  Chi, N.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Metabolomics 44%
  • Rehabilitation 20%
  • Taiwan 13%
  • Biomarkers 8%

• The Association between Plasma Folate and Selenium Concentrations, Gene Polymorphisms of Selenoprotein and One Carbon Metabolism Related Enzymes and Developmental Delay in Preschool Children

  Hsueh, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Preschool Children 100%
  • Arsenic 88%
  • Selenoproteins 47%
  • Selenium 45%
  • Cystathionine 38%

• Sub-Project 1: Mechanisms and Effects of Paired Associative Nerve Stimulation in Spinal Cord Injured Animal Models( I )

  Peng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 高氧誘導的肺損傷由新生小鼠的肺和腸道微生物群相介導

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats

  Peng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Deep Brain Stimulation 100%
  • Traumatic Brain Injury 76%
  • Brain 29%
  • Urinary Bladder 27%
  • Urination 19%

• Characterization of Molecular and Pathological Role of Hs 1-Associated Protein X-1(Hax-1) in Cisplatin Induced Nephorotoxicity via Hax-1 Conditional Knock out Mice

  Lin, H. & Chen, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cisplatin 100%
  • Kidney 45%
  • Knockout Mice 31%
  • Renal Insufficiency 22%
  • Wounds and Injuries 16%

• Study on the Developmnt and Application of Nuclear Medical Assessment Model for Brain Inflammation by Angiostrongylus Cantonesis Infection

  Cheng, P.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • positron-emission tomography 100%
  • image analysis 40%
  • eosinophils 38%
  • brain 34%
  • infection 25%

• Epigenetic Editing as a Novel Therapeutics for Gynecological Cancer

  Lai, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epigenomics 100%
  • Clustered Regularly Interspaced Short Palindromic Repeats 43%
  • Tumor Biomarkers 27%
  • Neoplasms 24%
  • Gene Editing 23%

• Evaluate the Molecluar Mechanims and Clinical Application on ATF3 Regulated microRNA

  Lin, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 43%
  • Kidney 29%
  • Biomarkers 17%
  • Activating Transcription Factor 3 14%