Projects per year
- 1,850 - 1,900 out of 2,493 results
Search results
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Finished
Molecular Epidemiological Study of Renal Cell Carcinoma---Arsenic Methylation Capability, 8-OHdG and Polymorphism of IRS and RAAS Exploration
Hsueh, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Mechanisms Underlying Airway Hypersensitivity Induced by Hydrogen Sulfide
8/1/14 → 10/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Investigation of Mechanisms of SSRI Antidepressants and GABAAR Modulators Inhibit High-Grade Glioma Invasion
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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A Multidisciplinary Study of the Pathophysiology of Blast-Induced Mild Traumatic Brain Injury
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色:經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成酉每)的調控與白蘆黎醇/史達汀臨床治療及應用(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Genomic and Non-Genomic Estrogen Effects on the Spinal NR2B-Related Uterus-Colon Crosstalk in Rats
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function in
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Biomarkers Associated with Toll-Like Receptors and Neuroimage Study in Ischemic Stroke Patients (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Explore the Molecular Mechanisms and Application of microRNA-16 in In Acute Kidney Injury
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Relationship between Lumbar Vertebral Perfusion and Fat Marrow Content in Normal Subjects, Osteoporosis and Bone Metastases Using DCE-MRI and Fat-Water Separation
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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榖胱甘月太硫轉移酉每參與乳癌致癌之分子機制探討(3/3)
Wu, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.
Ho, Y. & Wu, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Oncolytic Measles Virus for the Treatment of Breast Adenocarcinoma
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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組蛋白去甲基酉每JARID1B基因在肺腺癌之腫瘤形成與影響腫瘤生物行為機轉之探討(1/2)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Investigation of Glioblastoma Cell-Secreted microRNA Signatures and Their Functional Effects on Tumor Angiogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Chitosan Nanoparticle as a Macrophage-Targeting Drug Delivery Carrier
8/1/14 → 8/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Effect of Endothelin-1 on Myofibroblast Transformation of Pleural Mesothelial Cells and Its Implications for Pleural and Pulmonary Fibrosis
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Characterization of 5-Hydroxymethylcytosine and Ten-to-Eleven Translocation Gene (TET) in Cervical Cancer
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Unraveling the Impact of Deletion of Androgen Receptor on Brain Trauma
Yang, L.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Study of Mechanotransduction in Hair Cell
8/1/14 → 12/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Functional Electrical Stimulation Cycling and Central Neuromodulation on Motor Control in Stroke
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women.
Hsu, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Reflex Pelvic Floor Muscle Activities in Women with Urinary Incontinence (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Application and Mechanism of Novel Fluoro-Rutaecarpine on Inhibition of Inflammation Induced Endomt
8/1/14 → 12/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Indoor Air Quality Improvement on Cardiovascular Health in General Population
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Relationship and Predictors of Electrocardiography, Inflammatory Markers, Clinical Features in Older Bipolar and Schizophrenia Patients Concurrent with Coronary Heart and Cerebro-Vascular Diseases
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Efficacy Studies of Tn-Directed Therapeutic Antibody and Immunotoxin in Syngeneic Mouse Tumor Models
Hwang, J.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Effects of the APOE4 Allele on Cerebral Structural and Functional Connectivity---A Diffusion Tensor Imaging and Resting-State MRI Study
Chen, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Application of Scaffold in Ovarian Transplantation for Female Fertility Preservation---An in vivo Transgenic Mouse Model (I)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Role of Oxidative Stress-triggered Redox Adaptation Mechanism and Genetically Endowed Expression Profile of Antioxidant Enzymes in the modulation of Intrinsic and Acquired Chemoand Radio-resistance of Human Hepatocellular Carcinoma Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Evaluate the Radio-Biological Roles of miR-17-5P in Oral Cancer Cell Line OC3
Wu, S.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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探討不同選擇作用之組織蛋白去乙醯?調節成分抑制神經發炎之機制及其對腦內出血與腦炎之治療特性評估(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Evaluation of the Mechanism of Post-Traumatic Immunosuppression---The Role of TLR4 Trafficking and microRNA
Lin, J. A.
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Influence of Porphyromonas gingivalis Groel in Vascular Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Role and Molecular Mechanism of PPARα in Acute Kidney Injury---Focus on the Protective Effect in Renal Tubular Cell
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Evaluate the Molecluar Mechanims and Clinical Application on Atf3 Regulated microRNAs
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關,曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能,包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義,這也促使我們想要釐清E1A抑制癌症的機制。因此,我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣,並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示,E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中,GRP78所扮演的生物功能及其調控的機轉。為了達到此目的,我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標: 目標一:探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二:研究E1A抑制GRP78表現之分子機轉 目標三:於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四:探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外,藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Association Study of Persistent Metabolic Syndrome, Inflammatory Markers, Adipose Markers and Mild Cognitive Decline
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council
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The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model(2/3)
Chang, C. & Chiang, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › a - National Health Research Institutes
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The Effect of Muscle Strength Training on Body Composition and Sarcopenic Obesity among the Female Overweight Elderly
8/1/14 → 7/31/15
Project: A - Government Institution › b - National Science and Technology Council