School of Medical Laboratory Science and Biotechnology

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2020 2021 2022 2023 2024

• 193 Finished

Projects per year

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• Finished

  新聘教師研究補助

  Wang, L.-T. (PI)

  11/1/23 → 10/31/24

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 探究粒線體衍胜肽對粒線體功能障礙的細胞保護作用(3/3)

  Kao, S.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討HMGCS2基因調控酮體生成與能量代謝轉換對抗藥性肝癌之影響(2/2)

  Liao, Y.-J. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 糖尿病的心血管風險：新穎性抗丙二醛修飾胜肽加成物自體抗體在血漿中的致病角色並導入機器學習以預測第二型糖尿病合併冠狀動脈疾病

  Lin, C.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 裝載GM-CSF及標靶奈米粒子疫苗之水膠複合系統用於原位募集並活化樹突細胞以增強腫瘤特異性免疫反應達到抑制癌症轉移之功效(3/3)

  Pan, W.-Y. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以跨世代活體高轉移乳癌模型與全基因組剔除(GeCKO)分析模式探討尿苷雙磷酸葡萄糖醛酸基轉移酶2B7(UGT2B7)標靶抗癌機制

  Lee, C.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 類澱粉蛋白損害類固醇生成之分子基礎探討

  Kao, S.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 建立SARS-CoV-2 nsp5內切酶活性冷光檢測平台篩選抗病毒藥物-以Omicron變異株為例

  Lee, C.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• CDK Inhibitor-Mediated PD-L1 Upregulation Enhances OC Responsiveness to CAR-Based Regimen Targeting

  Liu, C.-L. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• ERO1α在維持癌幹細胞與治療腫瘤細胞的角色

  Liang, Y.-C. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討肝癌細胞長期暴露低劑量塑化劑後對sorafenib感受性的影響及其分子機制

  Liao, Y.-J. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以活體肺轉移研究平台與全基因剔除模式(GeCKO)探討未分化甲狀腺癌轉移與基因調控-以TNFRSF19、CTDP1基因開發抗甲狀腺癌策略為例

  Lee, C.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 人類卵巢顆粒細胞中粒線體動態平衡對於類固醇荷爾蒙生成的影響

  Kao, S.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 粘質沙雷氏菌流行病學及轉錄體適應性之分析

  Wu, C.-J. (PI)

  3/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討環形核糖核酸hsa_circ_0002512及 hsa_circ_0080210在促進胰臟腫瘤發展上的機制

  Liang, Y.-C. (PI)

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新聘教師研究補助

  Wu, C.-J. (PI)

  11/1/22 → 10/31/23

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 經由垂直性群組研究與分子調控機制探討腸道代謝物和腸道菌叢對慢性腎病進程之影響

  Lin, J.-C. (PI)

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Understanding the Cytoprotective Effects of Mitochondrial-Derived Peptides on Mitochondrial Dysfunction(2/3)

  Kao, S.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Effects of Hmgcs2 Mediated Ketone Production and Metabolic Shift in Sorafenib-Resistant Hepatocellular Carcinoma (1/2)

  Liao, Y.-J. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• PAR1嵌合抗體T細胞及T調節細胞在臨床治療上的多功能應用

  Liu, C.-L. (PI)

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Nanocomposite Hydrogel-Delivered Gm-Csf and Targeting Nanoparticle Vaccine That Can Recruit and Activate Dendritic Cells in Situ for Enhancing Tumor-Specific Immune Responses to Inhibit Cancer Metastasis

  Pan, W.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Development of a Novel Therapeutic Strategy for Triple Negative Breast Cancers (Tnbc) through Targeting Udp-Glucuronosyltransferase 2b7 (Ugt2b7)( III )

  Lee, C.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 長期暴露低劑量塑化劑對肝癌藥物 （sorafenib）感受性的影響

  Liao, Y.-J. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 粒線體衍生肽對於細胞自噬作用的影響

  Kao, S.-H. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎PDI抑制劑誘導鐵死亡之研究

  Liang, Y.-C. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• Clinical Assay for Colorectal Carcinoma Early Detection Using Wheat Germ Agglutinin-Multiple Reaction Monitoring Mass Spectrometry Kit: U.S. Fda Guideline

  Lin, C.-Y. (PI)

  6/1/22 → 5/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Understanding the Cytoprotective Effects of Mitochondrial-Derived Peptides on Mitochondrial Dysfunction

  Kao, S.-H. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Studies on the Mechanisms of Histamine N-Methyl-Transferase (Hnmt) as a Novel Molecular Marker to Help Clinician for Identifying of Herceptin Responder in Breast Cancer Patients

  Ho, Y.-S. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Development of a Novel Therapeutic Strategy for Triple Negative Breast Cancers (Tnbc) through Targeting Udp-Glucuronosyltransferase 2b7 (Ugt2b7)( II )

  Lee, C.-H. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Roles of Npc2 Mediated Free Cholesterol Homeostasis in the Sorafenib-Resistant Hepatocellular Carcinoma( III )

  Liao, Y.-J. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Explore of the Α9-Nicotinic Acetylcholine Receptor/Her2 Proteins Complex as Molecular Targets for Developing Rna Nanomedicine on Herceptin® Resistant Breast Cancer Cells( II )

  Ho, Y.-S. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Study of Ero1a on the Roles of Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma

  Liang, Y.-C. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Nanocomposite Hydrogel-Delivered Gm-Csf and Targeting Nanoparticle Vaccine That Can Recruit and Activate Dendritic Cells in Situ for Enhancing Tumor-Specific Immune Responses to Inhibit Cancer Metastasis

  Pan, W.-Y. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Emerging Impact of Gut Microbiota-Gut Metabolite-Host Posttranscriptional Event Network on Manipulating Gut Homeostasis or Carcinogenic Signature of Colorectal Cancer Cells

  Lin, J.-C. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Ovarian Cancers with Chimeric Antigens Receptor (Cars) T-Cells Mediated Immunotherapy

  Liu, C.-L. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 以玻尿酸合成酶為平台探討RNA適體奈米質粒抑制乳癌之機制

  Ho, Y.-S. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• miR-1作為非小細胞肺癌對歐洲紫杉醇敏感性的調節機制探討

  Liu, J.-J. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• Artemisia santolinifolia對頭頸癌細胞生長抑製及其機制研究

  Liu, J.-J. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討酮體對肝癌細胞sorafenib感受性影響

  Liao, Y.-J. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討ERO1α經由c-Met調控腫瘤細胞移動的分子機制

  Liang, Y.-C. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 以CRISPR/Cas9建立exosome-free研究模式探討外泌體(exosome)調控三陰性乳癌轉移機制

  Lee, C.-H. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 以CRISPR/cas9開發三陰性乳癌轉移中iPS相關基因作為標靶研究平台

  Lee, C.-H. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 開發ㄧ奈米粒子水膠複合系統作為手術後的DNA疫苗以預防癌症之復發

  Pan, W.-Y. (PI)

  11/1/20 → 10/31/21

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Pan, W.-Y. (PI)

  10/1/20 → 9/30/21

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Investigate the Genetic Diagnosis of Pearson Syndrome and the Feasibility of Selective Removal of Deleted Mitochondrial Dna in the Patient-Derived Cells

  Kao, S.-H. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 探討ARE結合蛋白質與選擇性聚腺甘酸化作用在人類大腸直腸癌上所扮演的角色(3/3)

  Liang, Y.-C. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Generation, Characterization and Humanization of Chicken-Derived Single Chain Antibody against Venom Proteins Using Phage Display Technology

  Yang, Y.-Y. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Studies on the Mechanisms of Histamine N-Methyl-Transferase (Hnmt) as a Novel Molecular Marker to Help Clinician for Identifying of Herceptin Responder in Breast Cancer Patients

  Ho, Y.-S. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯 研究-乳癌細胞α9尼古丁受體/HER2複合體作為RNA奈米藥物治療HerceptinR抗藥 性之機制探討(1/3)

  Ho, Y.-S. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Study the Roles of Npc2 Mediated Free Cholesterol Homeostasis in the Sorafenib-Resistant Hepatocellular Carcinoma( II )

  Liao, Y.-J. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council