Projects per year
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以樹突棘發育相關的mRNA為作用目標,建立由TDP-43和FMRP共同調控 參與 的神經疾病發病機制:藉此尋找新的藥物靶標(3/3)
9/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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整合大腦健康指標與多樣生物標記軌跡及多基因風險分數發展精準的中風後認知功能障礙軌跡預測模型
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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TNKS / PI31訊息傳遞路徑在TDP-43相關神經病變中調控蛋白酶體之機制(3/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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研究趨化因子-CCL5及其受體在神經新生和分化中的作用機制(1/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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探討BMX與Wnt/beta-catenin訊息傳遞路徑對腦外傷後認知功能缺失的調控機制(2/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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哺乳類動物DNA甲基化酶的新功能─去DNA甲基化活性的生理角色, 調控機制, 與轉譯研究(3/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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透過調整腫瘤細胞中的類固醇合成至别孕烷醇酮和重新編程脂肪酸代謝來促進自然殺手細胞治療膠質母細胞瘤
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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一個重要RNA結合蛋白標的TDP-43的神經功能及它在神經退化疾病上的角色(2/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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脂質薑黃素顆粒(SLCP)在體內對mTOR訊息路徑的作用–尋求以疾病機制為基礎對結節性硬化症(TSC)癲癇的治療策略(3/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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以多模態人工智慧機器學習區辨發展遲緩與泛自閉症症候群幼兒及結合複合式早療介入成效進行幼兒語言發展預測(2/3)
8/1/23 → 7/31/24
Project: A - Government Institution › b - National Science and Technology Council
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112年度【治療重症地中海貧血與鐮刀型貧血候選藥物AS-28之臨床前試驗(I)】
7/1/23 → 12/31/23
Project: A - Government Institution › b - National Science and Technology Council
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利用鼻腔給藥探討CCL5對成年小鼠神經新生與改善神經功能的效用
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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探討親職壓力對於親代注意力與兒童語言發展遲緩的關聯性
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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以超高速腦波掃描探討語言發展遲緩幼兒於腦間同步性之神經特徵指標:以親子共讀過程為例
7/1/23 → 2/29/24
Project: A - Government Institution › b - National Science and Technology Council
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探討前列腺素E2調節之神經細胞活化在神經膠質母細胞瘤產生帝盟多抗性中的角色
3/1/23 → 2/29/24
Project: C - Project of Alliance › o - Chi Mei Medical Center
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深入探討CCL5對於微小膠細胞活化與神經軸突修復的相關性
3/1/23 → 2/29/24
Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital
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CCL5 在神經退化性疾病的早期認知障礙和行為障礙中的影響
1/1/23 → 12/31/23
Project: B - Project of TMU › h - Higher Education Sprout Project
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探討結節性硬化症相關病徵之病理機制-尋求以疾病機制為基礎的治療策略
1/1/23 → 12/31/23
Project: B - Project of TMU › h - Higher Education Sprout Project
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針對人類生命週期各階段開發精準神經調節策略以提升認知功能
1/1/23 → 12/31/23
Project: B - Project of TMU › h - Higher Education Sprout Project
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Finished
以樹突棘發育相關的mRNA為作用目標,建立由TDP-43和FMRP共同調控 參與 的神經疾病發病機制:藉此尋找新的藥物靶標(2/3)
9/1/22 → 8/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Investigating the Effects of Peripheral Ptx3 Blockade on Alzheimer'S Disease Therapy (Ii)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Tnks/Pi31 Signal Cascade in the Spectrum of Proteasome Regulation under Tdp-43 Neuropathies(2/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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TNKS / PI31訊息傳遞路徑在TDP-43相關神經病變中調控蛋白酶體之機制(2/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Using Machine Learning to Integrate Multi-Omics Approach in Order to Explore the Potential Biomarkers and Develop Accurate Prediction Model for Post-Stroke Cognitive Impairment
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Basic and Translational Research of the Active Dna De-Methylation Process by Mammalian Dna Methyltransferases- Physiological Functions and Regulatory Mechanisms
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Investigation of the Effects of Ccl5 Mediated Neuronal Energy Metabolism on Hippocampal Neurogenesis and Memory Formation under Normal and Alzehemier’S Disease Conditions
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Solid Lipid Curcumin Particle (Slcp) on Mtor Signaling in Vivo – Searching for a Mechanism-Based Therapeutic Strategy for Epilepsy in Tuberous Sclerosis Complex (Tsc) (2/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Study of Bmx and Wnt/Beta-Catenin Pathway on Cognitive Impairment after Traumatic Brain Injury (1/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Neuronal Function of the Rna-Binding Protein Tdp-43 and Its Dysfunction in Neurodegenerative Diseases (1/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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Predicting Language Development and Classification in Toddlers with Developmental Delays and Autism Spectrum Disorders by Applying Multimodal Data to Artificial Intelligence/Machine Learning and Combining the Therapeutic Efficacy of Early Intervention (1/3)
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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The Role of Fatty Acid Metabolic Reprogramming Associated with Mitochondrial Dna Mutations in the Drug Resistance of Glioblastoma
8/1/22 → 7/31/23
Project: A - Government Institution › b - National Science and Technology Council
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探討高密度脂蛋白膽固醇和缺血性中風預後的因果相關性:雙樣本孟德爾隨機化分析
7/1/22 → 2/28/23
Project: A - Government Institution › b - National Science and Technology Council
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Characterization of Sleep Disturbance during Disease Progression in Tuberous Sclerosis Complex
7/1/22 → 2/28/23
Project: A - Government Institution › b - National Science and Technology Council
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探討神經類固醇用於診斷及治療神經退化性疾病之潛力
3/1/22 → 2/28/23
Project: C - Project of Alliance › o - Chi Mei Medical Center
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To study the effect of CCL5 on immune regulation and therapy effect through nasal administration after mild brain injury
3/1/22 → 2/28/23
Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital
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Investigating Nerve Regeneration Following Traumatic Brain Injury( III )
2/1/22 → 1/31/23
Project: A - Government Institution › b - National Science and Technology Council
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闡明化療對前列腺素E2介導的膠質母細胞瘤和神經元之間交互作用的影響
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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探討癌症相關纖維母細胞在多形性膠質母細胞瘤發展過程中的影響
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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探討親職壓力與親子互動刺激對衝動/注意力缺失高風險幼兒的神經語言發展影響
1/1/22 → 12/31/22
Project: B - Project of TMU › h - Higher Education Sprout Project
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Investigating the Effects of Peripheral Ptx3 Blockage for Alzheimer'S Disease Therapy
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Investigate Neuroimaging-Based Neural Substrate of Social Communication Deficits for Early Diagnosis and Predicting the Efficiency of Early Intervention for Toddlers with Autism Spectrum Disorders
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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To Clarify the Role of Neurosteroids Metabolism in Drug Resistance in Glioblastoma( III )
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Basic and Translational Study of the Neuronal Functions of Tdp-43 Protein and Its Dysfunction in Neurodegenerative Diseases( III )
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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The Effect of Guidance Receptor/Ligand Cis-Attenuation on Neural Circuit Assembly in Spinal Motor Neurons
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Studying the mechanism of CCL5/RANTES in neuro protection in a brain injury mouse mode –memory neurite circuit activation after injury
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Effects of Solid Lipid Curcumin Particle (Slcp) on Mtor Signaling in Vivo – Searching for a Mechanism-Based Therapeutic Strategy for Epilepsy in Tuberous Sclerosis Complex (Tsc)
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Basic and Translational Research of the Active Dna De-Methylation Process by Mammalian Dna Methyltransferases- Physiological Functions and Regulatory Mechanisms
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Tnks/Pi31 Signal Cascade in the Spectrum of Proteasome Regulation under Tdp-43 Neuropathies
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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Revealing Benefits and Mechanisms of Ceemt (Combined Environmental Enrichment and Music Therapy) on Cognition, Depression and Anxiety after Traumatic Brain Injury
8/1/21 → 7/31/22
Project: A - Government Institution › b - National Science and Technology Council
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實體及多媒體音樂語言介入模式對疑似語言發展遲緩幼兒詞彙量擴充及腦部神經發展之影響
7/1/21 → 2/28/22
Project: A - Government Institution › b - National Science and Technology Council