Ph.D. Program in Drug Discovery and Development Industry

Projects

Projects per year 2010 2012 2013 2014 2015 2027

• 10 Active
• 303 Finished

Projects per year

Search results

• Active

  新聘教師研究補助

  Rao, N. V. (PI)

  1/20/25 → 1/19/26

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 新穎 NLRP3 發炎小體小分子抑制劑用於慢性腎病之研究開發

  Huang, H.-S. (PI)

  1/1/25 → 12/31/25

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 113年度大專校院STEM領域及女性研發人才培育計畫: 「整合智慧型新藥研發跨領域女性人才培育計畫-以新藥創新創業為例」

  Pan, S.-L. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › d - Ministry of Education

• An Rgd-Modified Pendant Vinpocetine-Derived Hydroxamic Acid Hdac Inhibitor Derived from Raft Polymers as a Novel Drug Delivery System for Breast Cancer Therapy

  Rao, N. V. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

  • Novel Drug Delivery System 100%
  • Malignant Neoplasm 100%
  • Vinpocetine 100%
  • Breast Cancer 100%
  • Hydroxamic Acid 100%

• 運用互動教學模式以增進EMI教學之學習成效-以藥物設計與開發為例

  HuangFu, W.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › d - Ministry of Education

• Discovery of Bbb-Crossing Drugs Targeting Neuroinflammation for Glioblastoma( III )

  Liou, J.-P. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• 混合專題式問題導向教學策略以提升研究論文數據分析之能力

  Hsieh, Y.-C. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › d - Ministry of Education

• Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication

  Lee, S.-B. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• Click Chemistry and Suzuki Coupling Approach for the Construction of Small Molecule Bifunctional Inhibitors Targeting the Dna Damage Repair Pathways.

  Nepali, K. (PI)

  8/1/24 → 7/31/27

  Project: A - Government Institution › b - National Science and Technology Council

  • DNA Repair 100%
  • Suzuki Reaction 100%
  • Dna Damage 100%
  • Click Chemistry 100%
  • Pathway Inhibitor 50%

• 113年度「人工智慧技術應用於醫療服務場域治理研究計畫」

  Lee, C.-H. (PI)

  8/1/24 → 7/30/25

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Finished

  探討認知與精神障礙之細胞與分子機制並發展治療策略-以結節性硬化症為例

  Lee, Y.-C. (PI)

  1/1/24 → 12/31/24

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Pharmacological investigation of HDAC8 inhibitor in perturbationof chromatin replication

  Lee, S.-B. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 小分子結合位相之預測與分析

  Hsu, K.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › f - Other (Funded by Government)

• 健保資料庫相關法規研究計畫

  Lee, C.-H. (PI)

  8/1/23 → 7/30/24

  Project: D - Other Project

• Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication and Evaluation of Its Cancer Therapeutic Potential in Combination with Checkpoint Kinase Inhibitors

  Lee, S.-B. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation and Mechanism Validation of the Combination Therapy of Pan- or Selective Histone Deacetylase Inhibitors with Immune Checkpoint Blockade Agent

  Huang, H.-L. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• DYRK1B抑制劑於胰臟癌中之活體藥效測試

  Huang, H.-L. (PI)

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Investigation and Mechanism Validation of the Combination Therapy of Pan- or Selective Histone Deacetylase Inhibitors with Immune Checkpoint Blockade Agent

  Huang, H.-L. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 以無患子油治療牙周病和促進口腔黏膜及植牙骨癒合之機轉探討並製備其釋放水膠體

  Huang, H.-M. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Discovery of agents disturbing genome stability during chromatin replication (2nd-4th years)

  Lee, S.-B. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• International Training Program in Advanced Implant Dentistry and Digital Dentistry

  Huang, H.-M. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting replication stress in cancer therapy(II)

  Lee, S.-B. (PI)

  7/1/20 → 6/30/21

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Design and Potency Optimization of Kinase Inhibitors for Cancer Treatment(1/3)

  Hsu, K.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Study on the Use of Static Magnetic Field to Induce Mechanobiological Effects to Enhance the Killing Ability of Natural Killer Cell

  Huang, H.-M. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Discovery of Agents Disturbing Genome Stability during Chromatin Replication

  Lee, S.-B. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Integrated Bioinformatics Approaches to Study the Mechanisms and Discover Drugs of Hcv-Induced Type 2 Diabetes Mellitus(3/3)

  Hsu, K.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Therapeutic Potential and Molecular Mechanism of Natural Products for Platinum-Resistant Bladder Cancer(1/3)

  Chen, M.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Mechanism and Efficacy Investigation of Using Histone Deacetylase Inhibitors to Enhance the Immune Modulation of Immune Checkpoint Blockade Agent

  Huang, H.-L. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting replication stress in cancer therapy (I)

  Lee, S.-B. (PI)

  7/1/19 → 6/30/20

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 組蛋白去乙醯酶在血管認知功能損傷中的作用-組蛋白去乙醯酶調節者在血管認知損傷動物可作為新的治療

  Lai, M.-J. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 開發整合二維材料、智慧微機電與微尺度光學系統之智慧型微量血液凝血偵測系統-以智慧型手機為平臺整合電阻抗式凝血偵測晶片

  Huang, H.-M. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 發展抗肺纖維化劑-治療肺部纖維化小分子藥物之藥理活性機轉探討

  Chen, M.-C. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Construction of a Coronary Computed Tomographic Angiography-Based, Imaging/Physiology Mega-Databank to Develop Artificial Intelligence-Facilitated Automatic Diagnostic/Prediction Systems through a Multi-Center, Cross-Specialty Consortium(2/3)

  Lee, C.-H. (PI)

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation on the Effect and Mechanism of Static Magnetic Field Coupled with Magnesium Ion for Promoting Odontogensis and Migration of Wharton'S Jelly Mesenchymal Stem Cells

  Huang, H.-M. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Mesenchymal Stem Cell 100%
  • Magnesium Ion 100%
  • Odontoblast 44%
  • Dental Pulp Stem Cell 33%
  • Stem Cell 33%

• Tlk Function and Regulation in Chromatin Replication (2nd Years)

  Lee, S.-B. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Phosphotransferase 100%
  • Kinase 100%
  • Proteomics 11%
  • Replisome 5%
  • Epigenetics 5%

• Discovery and Design of Kinase Inhibitors for Cancer Treatment

  Hsu, K.-C. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Malignant Neoplasm 100%
  • Phosphotransferase Inhibitor 100%
  • Janus Kinase 45%
  • Phosphotransferase 36%
  • Drug Development 36%

• 研發選擇性非異羥肟酸組蛋白去乙醯酶 4抑制劑

  Hsu, K.-C. (PI)

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Huang, H.-L. (PI)

  5/1/18 → 4/30/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Integrated Bioinformatics Approaches to Study the Mechanisms and Discover Drugs of Hcv-Induced Type 2 Diabetes Mellitus( I )

  Hsu, K.-C. (PI)

  8/1/17 → 7/1/18

  Project: A - Government Institution › b - National Science and Technology Council

• Discovery of Selective Inhibitors for Oncoprotein Kinases

  Hsu, K.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Oncoprotein 100%
  • Protein Kinases 100%
  • Malignant Neoplasm 50%
  • Diseases 30%
  • Abdominal Cancer 20%

• Investigation on the Role of Cytoskeleton Reorientation and Calcium Ion Transportation in Static Magnetic Field Induced Mesenchymal Stem Cells Proliferation

  Huang, H.-M. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Cytoskeleton 100%
  • Calcium Ion 100%
  • Mesenchymal Stem Cell 100%
  • Cell Proliferation 100%
  • Magnetic Field 100%

• Tlk Function and Regulation in Chromatin Replication

  Lee, S.-B. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Histone 100%
  • DNA Synthesis 100%
  • Micrococcal Nuclease 50%
  • Copurification 50%
  • Chromosome Instability 50%

• Mechanism of Anticancer Activity of Dihydroartemisinin Derivatives for Colorectal Cancer Treatment

  Chen, M.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Dihydroartemisinin 100%
  • Dihydroartemisinin Derivative 100%
  • Colorectal Carcinoma 100%
  • Artemisinin 66%
  • Antitumor Activity 22%

• 藉由全方位探索新致病機制發現新的第2型糖尿病之肝臟治療靶點：基於慢性C型肝炎病毒感染模式到一般族群、連結基礎，生物信息學和臨床的系統性探討之轉譯研究－整合生物資訊方法研究C型肝炎誘發之第二型糖尿病的機轉與藥物開發(1/3)

  Hsu, K.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy

  Chuang, K.-H. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Arm 100%
  • Bispecific Antibody 100%
  • T Cell 100%
  • CD3 Antigen 63%
  • Colon 15%

• Anticancer Drug Discovery of New Tegafur-Derivatives for Colorectal Cancer Therapy(3/3)

  Chen, M.-C. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Cancer Therapy 100%
  • Anticarcinogen 100%
  • Tegafur 100%
  • Colorectal Carcinoma 100%
  • Drug Discovery 100%

• Design and Synthesis of Biaryl and Biphenylamino Sulfonamides as Novel Anticancer Agents

  Lai, M.-J. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Sulfonamide 100%
  • Anticancer Drug 100%
  • Hydroxamic Acid 66%
  • STAT3 Protein 50%
  • IC50 50%

• 分析TLK訊息傳遞網絡及其於染色質維護與防止腫瘤生成之功能

  Lee, S.-B. (PI)

  4/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Lee, S.-B. (PI)

  4/1/16 → 7/19/21

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 將生物資訊之方法和功能性研究應用於基因表達與乳癌危險性相關性

  Chang, W.-C. (PI)

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › q - Cathay General Hospital