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Collaborations and top research areas from the last five years
Profiles
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Che-Chang Chang
- The Ph.D. Program for Translational Medicine - Professor
- Graduate Institute of Biomedical Informatics - Joint-Appointment Associate Professor
- International Ph.D. Program for Translational Science - Joint-Appointment Associate Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Associate Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Associate Professor
- International Master Program for Translational Science - Joint Appointment Associate Prfoessor
- TMU Research Center of Drug Discovery - member
- TMU Research Center of Cell Therapy and Regeneration Medicine - member
- TMU Research Center of Cancer Translational Medicine - Member
Person: Researcher
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Wei-Chiao Chang
- Department of Clinical Pharmacy - Professor
- Master Program in Applied Epidemiology - Joint-Appointment Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Professor
- Ph. D. Program in the Clinical Drug Development of Herbal Medicine - Joint-Appointment Professor
- The Ph.D. Program for Translational Medicine - Joint-Appointment Professor
- Ph.D. Program in Medical Neuroscience - Joint-Appointment Professor
- TMU Research Center of Cancer Translational Medicine - Member
- TMU Research Center of Cell Therapy and Regeneration Medicine - member
Person: Researcher
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Mei-Chuan Chen
- Department of Pharmaceutical Sciences - Professor
- Graduate Institute of Pharmacognosy - Joint-Appointment Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Professor
- Ph. D. Program in the Clinical Drug Development of Herbal Medicine - Joint-Appointment Professor
- TMU Research Center of Thoracic Medicine - Member
Person: Researcher
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Pharmacological Investigation of Hdac8 Inhibitor in Perturbation of Chromatin Replication
Lee, S.-B. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Active Targeted Polymer Nanoparticles for Delivery of Structurally Engineered Olaparib-Based Poly (Adp-Ribose) Polymerase (Parp) Inhibitors for Triple-Negative Breast Cancer (Tnbc) Cancer Therapy and Leukemia Cancer Therapy.
Rao, N. V. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Click Chemistry and Suzuki Coupling Approach for the Construction of Small Molecule Bifunctional Inhibitors Targeting the Dna Damage Repair Pathways.
Nepali, K. (PI)
8/1/24 → 7/31/27
Project: A - Government Institution › b - National Science and Technology Council
Research output
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3,4-dihydroxybenzalacetone from Phellinus linteus reduces glial activation, mitigates oxidative stress and inflammation, and preserves retinal function in ischemia–reperfusion-like injury
Wu, L. H., Kuo, Y. H., Lin, F. L., Fitriana, I., Yang, C. H., Shen, Y. C., Liu, Y. C., Jiang, C. Y., Yen, J. L., Lee, Y. M., Cheng, Y. W. & Hsiao, G., Jan 2026, In: Experimental Eye Research. 262, 110762.Research output: Contribution to journal › Article › peer-review
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7,7”-dimethoxyagastisflavone induced MYCN/MYBL2-dependent apoptosis and metabolism reprogramming in Sonic Hedgehog medulloblastoma
Wu, Y. S., Lin, H. H., Wu, K. S., Huang, Y. T., Liao, J. Y., Chu, S. S., Wong, T. T., Hsieh, C. L., Chang, C. C., Sung, S. Y., Lin, C. Y. & Lin, Y. L., Dec 2026, In: Journal of Translational Medicine. 24, 1, 386.Research output: Contribution to journal › Article › peer-review
Open Access -
A heavy-chain antibody-drug conjugate targeting glycosylated CEACAM6 inhibits brain metastatic tumor growth
Tsai, Y. T., Yen, M. H., Hu, P. J., Lee, C. C., Liu, C. Y., Cheng, T. M., Shen, H. T., Benjamin Zhang, B. X., Lee, H. L., Chuang, K. H., Yap, C. V., Wang, W. C. & Wu, M. H., Jun 28 2026, In: Cancer Letters. 648, 218463.Research output: Contribution to journal › Article › peer-review
Datasets
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Additional file 5 of Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women
Tsai, K.-L. (Contributor), Chang, C.-C. (Creator), Chang, Y.-S. (Creator), Lu, Y.-Y. (Creator), Tsai, I.-J. (Contributor), Chen, J.-H. (Creator), Lin, S.-H. (Creator), Tai, C.-C. (Contributor), Lin, Y.-F. (Creator), Chang, H.-W. (Creator), Lin, C.-Y. (Creator) & Su, E.C.-Y. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.13889400.v1, https://springernature.figshare.com/articles/dataset/Additional_file_5_of_Isotypes_of_autoantibodies_against_novel_differential_4-hydroxy-2-nonenal-modified_peptide_adducts_in_serum_is_associated_with_rheumatoid_arthritis_in_Taiwanese_women/13889400/1
Dataset
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Additional file 1 of A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies
Wang, Y.-T. (Creator), Huang, B.-C. (Creator), Hsieh, Y.-C. (Creator), Ho, K.-W. (Creator), Cheng, T.-L. (Creator), Wang, J.-Y. (Creator), Liu, H.-J. (Creator), Tsai, H.-L. (Creator), Liao, J.-M. (Creator), Liu, Y.-L. (Creator), Hong, S.-T. (Creator), Chen, I.-J. (Creator), Su, Y.-C. (Creator) & Chuang, K.-H. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.19101789.v1, https://springernature.figshare.com/articles/journal_contribution/Additional_file_1_of_A_universal_in_silico_V_D_J_recombination_strategy_for_developing_humanized_monoclonal_antibodies/19101789/1
Dataset
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CCDC 1417633: Experimental Crystal Structure Determination
Liu, F.-L. (Creator), Chang, D.-M. (Creator), Chen, C.-L. (Creator), Chen, T.-C. (Creator), Liu, F.-C. (Creator), Ahmed Ali, A. A. (Contributor), Huang, H.-S. (Creator) & Lee, C.-C. (Creator), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc1jl53d, https://doi.org/10.5517%2Fcc1jl53d
Dataset