International Ph.D. Program for Translational Science

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2019 2025

• 1 Active
• 111 Finished

Projects per year

Search results

• Active

  Development and Optimization of an Anti-Ceacam6 Single Domain Antibody-Drug Conjugate to Improve Blood-Brain Barrier Permeability for Brain-Metastasis Cancer Therapy

  Wu, M.-H. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council
• Finished

  小分子結合位相之預測與分析

  Hsu, K.-C. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › f - Other (Funded by Government)

• Translational Research of Clinical Grade Placenta-Derived Mesenchymal Stem Cell (Pcmsc) Therapy on Post Ali/Ards Lung Fibrosis( III)

  Wu, M.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 發展高危險口腔癌前病變的精準預測模式及診斷治療策略

  Wu, M.-H. (PI)

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 111年度育苗「開發針對cetuximab抗藥性癌症的anti-CEACAM6重鏈抗體藥物」

  Wu, M.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

  File

  • Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 100%
  • CEACAM6 100%
  • Cetuximab 70%
  • Epidermal Growth Factor Receptor 60%
  • Epidermal Growth Factor 60%

• Translational Research of Clinical Grade Placenta-Derived Mesenchymal Stem Cell (Pcmsc) Therapy on Post Ali/Ards Lung Fibrosis( II )

  Wu, M.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 探討半乳糖凝集素-1調控ADAM17活性在新冠病毒導致發炎反應的角色

  Wu, M.-H. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 人類胎盤間葉幹細胞對急性肺損傷及氣喘免疫調控的臨床前評估

  Wu, M.-H. (PI)

  1/1/20 → 12/31/20

  Project: A - Government Institution › d - Ministry of Education

• 以基因影像學技術應用於分析高風險兒童髓母細胞瘤使用奈米藥物標靶治療之療效

  Hsieh, C.-L. (PI)

  1/1/20 → 12/31/20

  Project: A - Government Institution › d - Ministry of Education

• 蝦急性肝胰腺壞死病毒素 PirAvp 與 PirBvp 之轉錄調節機制探討

  Wang, H.-C. (PI)

  1/1/20 → 12/31/20

  Project: C - Project of Alliance › l - National Taiwan Ocean University

• 老化發炎現象所導致的外在調控可促進子宮內膜異位症的病程發展(I/II)

  Chen, Y.-F. (PI)

  1/1/20 → 12/31/20

  Project: A - Government Institution › d - Ministry of Education

• 發展標靶CEACAM6的口腔癌治療診斷方法

  Wu, M.-H. (PI)

  1/1/20 → 12/31/20

  Project: A - Government Institution › a - National Health Research Institutes

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X

  Wang, W.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(2/3)

  Wu, M.-H. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Exploration of the Pathogenesis of Acute Hepatopancreatic Necrosis Disease (Ahpnd) in Shrimp(3/3)

  Wang, H.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Investigation of the Regulatory Mechanism and Roles of Sentrin-Specific Protease 2 in Epithelial-Mesenchymal Transition and Breast Cancer Stemness

  Chang, C.-C. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• 以能量關聯線寬特性研製高靈敏微環型共振器之生物感測器

  Chang, C.-C. (PI)

  1/1/19 → 12/31/19

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 紫膜光電生物晶片應用於食安快速檢測之探討

  Wang, W.-C. (PI)

  1/1/19 → 12/31/19

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 人類胎盤間質幹細胞治療於急性及慢性肺損傷誘發肺纖維化：微環境、免疫調節、基因體/蛋白質體分析與臨床級細胞製備之臨床前轉譯研究-探討人類胎盤間質幹細胞調控肺纖維母細胞活化及肺組織纖維化的角色

  Wu, M.-H. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 神經內分泌型前列腺癌的轉譯研究-ADAM9在神經內分泌型前列腺癌的轉譯研究

  Sung, S.-Y. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 神經內分泌型前列腺癌的轉譯研究-L1CAM在神經內分泌型前列腺癌的轉譯研究

  Hsieh, C.-L. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 北醫大的表基因轉譯工作組-在人類幹細胞上的表觀基因工程研究

  Chen, Y.-F. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 受石斑虹彩病毒(grouper iridovirus)誘導表現之點帶石斑L型胺基酸氧化酶之免疫功能鑑定

  Wang, H.-C. (PI)

  1/1/19 → 12/31/19

  Project: C - Project of Alliance › l - National Taiwan Ocean University

• Evolution Haptoglobins as Protein Drugs for Coronary Artery Diseas

  Cheng, T.-M. (PI)

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Haptoglobin 100%
  • Coronary Artery 100%
  • Coronary Artery Disease 80%
  • Inflammation 50%
  • Atherosclerosis 30%

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X(2/3)

  Wang, W.-C. (PI)

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Galectin-3 in Ceacam6 Enhanced Egfr Signaling and Its Implication in Head and Neck Cancer Therapy

  Wu, M.-H. (PI)

  8/1/18 → 7/30/20

  Project: A - Government Institution › b - National Science and Technology Council

  • Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 100%
  • Galectin 3 100%
  • Head and Neck Cancer 100%
  • Neck 100%
  • CEACAM6 100%

• The Role of Intracellular and Extracellular Ubiquitin Machinery in Modulation of Breast Cancer Tumorigenesis, Metastasis and Tumour Microenvironment

  Chang, S.-C. (PI)

  8/1/18 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

  • Breast Cancer 100%
  • Ubiquitin 100%
  • Tumor Microenvironment 100%
  • Carcinogenesis 100%
  • Ubiquitins 100%

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.-F. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Sarcopenia 100%
  • Muscle Disease 100%
  • Ribonucleotide Reductase 100%
  • Skeletal Muscle 100%
  • Mouse Model 66%

• Investigation of the Cytotoxic Mechanism of Photorhabdus Luminescens Pirapl and Pirbpl Toxins by Using Structural and Proteomic Approaches

  Wang, H.-C. (PI)

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Photorhabdus luminescens 100%
  • Photorhabdus 100%
  • Proteomics 100%
  • Glibenclamide 100%
  • Infectious Agent 66%

• Study of the Role of L1cam on Neuroendocrine Prostate Cancer Progression

  Hsieh, C.-L. (PI)

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Cancer Growth 100%
  • Prostate Cancer 100%
  • Cell Adhesion Proteins 50%
  • Castration Resistant Prostate Cancer 13%

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(I)(1/3)

  Wu, M.-H. (PI)

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• 探討人類胎盤蛻膜間葉幹細胞對肝臟纖維化的治療效果：聚焦免疫調節腫瘤壞死基因-α在肝臟星狀細胞的訊息傳遞(先期補助)

  Wu, M.-H. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• Molecular and Translational Study of L1cam in Metastatic Castraction Resistant Prostate Cancer (Mcrpc)

  Hsieh, C.-L. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Prostate Cancer 100%
  • Cell Adhesion Proteins 100%
  • Cell Signaling Pathway 17%
  • Signaling Protein 17%
  • Bone Metastasis 11%

• To Investigate the Role of N-Linked Glycosylated Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Ceacam6) in Egf Receptor Signaling and the Implication in Oral Cancer Therapy

  Wu, M.-H. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 100%
  • Epidermal Growth Factor Receptor 100%
  • Mouth Cancer 100%
  • CEACAM6 100%
  • Glycosylation 36%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Sumoylation 100%
  • Protease 100%
  • Transforming Growth Factor Beta 80%
  • Transforming Growth Factor Beta Induced 30%
  • MMP9 20%

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.-F. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Sarcopenia 100%
  • Muscle Disease 100%
  • Ribonucleotide Reductase 100%
  • Skeletal Muscle 100%
  • Mouse Model 66%

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X

  Wang, W.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

• Analysis the Role of Adam9 as Novel Biosignature in Prostate Cancer Malignant Progression

  Sung, S.-Y. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Prostate Cancer 100%
  • ADAM9 100%
  • Cancer Growth 36%
  • Metastatic Carcinoma 27%
  • Biological Marker 27%

• Exploring the Potential Applications of Dna Mimic Protein Saugi in Viral Diseases and Mrsa by Structure-Based Study

  Wang, H.-C. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Viral Disease 100%
  • Human Immunodeficiency Virus 100%
  • Herpes Simplex Virus 100%
  • Staphylococcus Aureus 100%
  • Competitive Inhibition 50%

• 探討高尿酸血症(痛風)病人與日後罹患阿茲海默症疾病風險的相關性研究

  Yang, W.-C. (PI)

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - National Science and Technology Council

• Creating the SUMOylated-factor specific antibody and the application in biochemical analysis

  Chang, C.-C. (PI)

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating a Key Switch between Immune-Overactivation and Tumorigenesis

  Chang, S.-C. (PI)

  2/1/17 → 10/31/17

  Project: A - Government Institution › b - National Science and Technology Council

• 使用級聯低同調干涉之表面電漿技術於微小核醣核酸相位感測

  Chang, C.-C. (PI)

  1/1/17 → 12/31/17

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• 半乳糖凝集素-1影響肝纖維化促進肝癌進程的探討

  Wu, M.-H. (PI)

  1/1/17 → 12/31/17

  Project: A - Government Institution › a - National Health Research Institutes

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C.-L. (PI)

  8/1/16 → 8/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Prostate Cancer 100%
  • Bone Marrow Derived Mesenchymal Stem Cell 100%
  • Osteoplasty 100%
  • Bone Remodeling 100%
  • Bone Marrow-Derived Mesenchymal Stem Cells 100%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis(3/3)

  Wu, M.-H. (PI)

  8/1/16 → 9/30/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Galectin-1 100%
  • Glycosylation 100%
  • Hepatic Stellate Cell 100%
  • Neuropilin 1 100%
  • Liver Fibrosis 100%

• 不同表現型之血紅素結合蛋白在缺血性心臟病之功能差異及其重組次單元當缺血性心臟病胜?藥評估

  Cheng, T.-M. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

• ADAM9 調節 integrin b4 之轉換率以促使前列腺癌細胞移動及浸潤之研究(3/3)

  Sung, S.-Y. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Integrin 100%
  • ADAM9 100%
  • Metastatic Carcinoma 90%
  • Hemidesmosome 70%
  • Cancer Cell 40%

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.-F. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Sarcopenia 100%
  • Muscle Disease 100%
  • Ribonucleotide Reductase 100%
  • Skeletal Muscle 100%
  • Mouse Model 66%

• Uncovering the Specific Interactions between DNA Mimic Proteins and Their Target DNA Binding Proteins by Structure-Based Studies(3/3)

  Wang, H.-C. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Neisseria 100%
  • Uracil-DNA Glycosylase 100%
  • Staphylococcus Aureus 100%
  • Histone 100%
  • DNA-binding Protein 100%