Projects per year
Organisation profile
Organisation profile
The International Ph.D. Program for Translational Science in TMU (Taipei Medical University) provides comprehensive training programs for clinical and translational researches. In this program, we combine expertise from various fields including molecular biology, cancer biology, animal model, aging, proteomic and structural biology, and focus on the discovery and development of clinical biomarkers for oncology, neuroscience, reproductive medicine, stem cell and regenerative medicine. By translating the results of benchside research into bedside treatments, we look forward to enhancing the bio-pharmaceutical research, as well as improving the quality of clinical diagnosis and medical care.
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Collaborations and top research areas from the last five years
Profiles
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Che-Chang Chang
- The Ph.D. Program for Translational Medicine - Professor
- Graduate Institute of Biomedical Informatics - Joint-Appointment Associate Professor
- International Ph.D. Program for Translational Science - Joint-Appointment Associate Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Associate Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Associate Professor
- International Master Program for Translational Science - Joint Appointment Associate Prfoessor
- TMU Research Center of Drug Discovery - member
- TMU Research Center of Cell Therapy and Regeneration Medicine - member
- TMU Research Center of Cancer Translational Medicine - Member
Person: Researcher
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Shu-Chun Chang
- The Ph.D. Program for Translational Medicine - Associate Professor
- International Ph.D. Program for Translational Science - Joint-Appointment Associate Professor
- Graduate Institute of Biomedical Informatics - Joint-Appointment Associate Professor
- International Master Program for Translational Science - Joint Appointment Associate Professor
- TMU Research Center of Cell Therapy and Regeneration Medicine - member
Person: Researcher
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Yi-Fan Chen
- International Master Program for Translational Science - Professor
- Graduate Institute of Biomedical Informatics - Joint-Appointment Professor
- International Ph.D. Program for Translational Science - Joint-Appointment Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Professor
- The Ph.D. Program for Translational Medicine - Joint-Appointment Professor
- TMU Research Center of Cancer Translational Medicine - Member
- TMU Research Center of Cell Therapy and Regeneration Medicine - Member
Person: Researcher
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探討在癌化過程中ACSL1調節免疫監視的機制與其應用
Tsai, C.-H. (PI)
1/1/26 → 12/31/26
Project: B - Project of TMU › i - Other (Funded by TMU)
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Metabolic Reinvigoration of Immune Tolerance for Hepatocellular Carcinoma Immune Therapy( III )
Tsai, C.-H. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
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Exploring the Potential of Aphbvp Transcription Factor as a Drug Target against Acute Hepatopancreatic Necrosis Disease (Ahpnd)
Wang, H.-C. (PI)
8/1/25 → 7/31/26
Project: A - Government Institution › b - National Science and Technology Council
Research output
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2-Hydroxyl hispolon reverses high glucose-induced endothelial progenitor cell dysfunction through the PI3K/Akt/eNOS and AMPK/HO-1 pathways
Wang, T. J., Hou, W. C., Hsiao, B. Y., Lo, T. H., Chen, Y. T., Yang, C. H., Shih, Y. T. & Liu, J. C., 2026, In: British Journal of Pharmacology. 183, 1, p. 189-211 23 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
7,7”-dimethoxyagastisflavone induced MYCN/MYBL2-dependent apoptosis and metabolism reprogramming in Sonic Hedgehog medulloblastoma
Wu, Y. S., Lin, H. H., Wu, K. S., Huang, Y. T., Liao, J. Y., Chu, S. S., Wong, T. T., Hsieh, C. L., Chang, C. C., Sung, S. Y., Lin, C. Y. & Lin, Y. L., Dec 2026, In: Journal of Translational Medicine. 24, 1, 386.Research output: Contribution to journal › Article › peer-review
Open Access -
A heavy-chain antibody-drug conjugate targeting glycosylated CEACAM6 inhibits brain metastatic tumor growth
Tsai, Y. T., Yen, M. H., Hu, P. J., Lee, C. C., Liu, C. Y., Cheng, T. M., Shen, H. T., Benjamin Zhang, B. X., Lee, H. L., Chuang, K. H., Yap, C. V., Wang, W. C. & Wu, M. H., Jun 28 2026, In: Cancer Letters. 648, 218463.Research output: Contribution to journal › Article › peer-review
Datasets
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Additional file 9: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Contributor), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Contributor), Hsu, Y.-L. (Contributor), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Unknown Publisher, Jan 6 2019
DOI: 10.6084/m9.figshare.7552553.v1, https://springernature.figshare.com/articles/Additional_file_9_of_Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/7552553/1
Dataset
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Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis
Hung, P.-F. (Creator), Hong, T.-M. (Contributor), Chang, C.-C. (Contributor), Hung, C.-L. (Creator), Hsu, Y.-L. (Creator), Chang, Y.-L. (Contributor), Wu, C.-T. (Contributor), Chang, G.-C. (Contributor), Chan, N.-L. (Contributor), Yu, S.-L. (Contributor), Yang, P.-C. (Contributor) & Pan, S.-H. (Contributor), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4356413.v1, https://springernature.figshare.com/collections/Hypoxia-induced_Slug_SUMOylation_enhances_lung_cancer_metastasis/4356413/1
Dataset
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3VJZ : Crystal structure of the DNA mimic protein DMP19
Wang, H.-C. (Contributor), Wang, A.H.-J. (Contributor) & Ko, T.-P. (Contributor), RCSB-PDB, 2012
DOI: 10.2210/pdb3vjz/pdb, https://www.rcsb.org/structure/3VJZ
Dataset