International Master/Ph.D. Program in Medicine

2025

A Deep Learning and PSSM Profile Approach for Accurate SNARE Protein Prediction

Kha, Q. H., Nguyen, H. P. L. & Le, N. Q. K., 2025, In: Methods in molecular biology (Clifton, N.J.). 2887, p. 79-89 11 p.

Research output: Contribution to journal › Article › peer-review

A ferritin-related dietary pattern is positively associated with iron status but negatively associated with vitamin D status in pregnant women: a cross-sectional study

Das, A., Bai, C. H., Chang, J. S., Huang, Y. L., Wang, F. F., Hsu, C. Y., Chen, Y. C. & Chao, J. C. J., Feb 2025, In: European Journal of Nutrition. 64, 1, 30.

Research output: Contribution to journal › Article › peer-review

Open Access

An in-depth review of AI-powered advancements in cancer drug discovery

Le, M. H. N., Nguyen, P. K., Nguyen, T. P. T., Nguyen, H. Q., Tam, D. N. H., Huynh, H. H., Huynh, P. K. & Le, N. Q. K., Mar 2025, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1871, 3, 167680.

Research output: Contribution to journal › Article › peer-review

Association between underlying health conditions and long COVID among non-hospitalized and hospitalized individuals as modified by health literacy: A multi-center study

Vo, H. T., Dao, T. V., Do, T. X., Do, B. N., Nguyen, T. T., Pham, K. M., Vu, V. H., Pham, L. V., Nguyen, L. T. H., Le, L. T. H., Nguyen, H. C., Tran, T. V., Nguyen, T. H., Nguyen, A. T., Nguyen, H. V., Nguyen, P. B., Pham, T. T. M., Dao, T. D., Le, T. T. & Nguyen, T. T. P. & 3 others, Tran, C. Q., Nguyen, K. T. & Duong, T. V., Jan 10 2025, (E-pub ahead of print) In: Public Health. 239, p. 87-93 7 p.

Research output: Contribution to journal › Article › peer-review

Bola-Amphiphilic Dendrimer Enhances Imatinib to Target Metastatic Ovarian Cancer via β-Catenin-HRP2 Signaling Axis

Shi, Z., Artemenko, M., Yu, W., Zhang, M., Yi, C., Chen, P., Lin, S., Bian, Z., Lian, B., Meng, F., Chen, J., Roussel, T., Li, Y., Chan, K. K. L., Ip, P. P. C., Lai, H. C., To, S. K. Y., Liu, X., Peng, L. & Wong, A. S. T., Jan 15 2025, In: ACS applied materials & interfaces. 17, 2, p. 2884-2898 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Camptothecin Triggers Apoptosis in Human and Mouse Drug-resistant Glioblastoma Cells via ROS-mediated Activation of the p53-p21-CD1/CDK2-E2F1-Bcl-xL Signaling Axis

Wu, G. J., Chen, J. T., Cherng, Y. G., Lin, C. J., Liu, S. H. & Chen, R. M., Feb 2025, In: Anticancer Research. 45, 2, p. 565-577 13 p.

Research output: Contribution to journal › Article › peer-review

Cerebral white matter damage in patients with end-stage kidney disease associates with cognitive impairment

Hou, Y. C., Tsai, C. C., Chen, R. M., Liu, Y. C., Lu, K. C., Chen, Y. L., Shen, T. W. & Wang, J. J., Jan 2025, In: Clinical Kidney Journal. 18, 1, sfae283.

Research output: Contribution to journal › Article › peer-review

Open Access

Chemical constituents from marine medicinal brown alga-derived Scytalidium lignicola SC228

Hsi, H. Y., Hsiao, G., Wang, S. W., Huang, S. J. & Lee, T. H., Jan 2025, In: Phytochemistry. 229, 114289.

Research output: Contribution to journal › Article › peer-review

Diagnostic performance of rapid on-site evaluation during bronchoscopy for lung cancer: A comprehensive meta-analysis

Chen, C. C., Lu, S. C., Chang, Y. K., Bai, C. H., Hsiao, K. Y., Lee, K. Y. & Wang, Y. H., Jan 2025, In: Cancer cytopathology. 133, 1, e22908.

Research output: Contribution to journal › Article › peer-review

Emerging Norovirus GII.12 infection in 2010 in Northern Taiwan

Tsai, C. N., Chang, Y. C., Chao, H. C., Hsu, Y. H., Wang, Y. H. & Chen, S. Y., Feb 2025, In: Journal of the Formosan Medical Association. 124, 2, p. 186-189 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

FIGO 2023 staging system predicts not only survival outcome but also recurrence pattern in corpus-confined endometrial cancer patients

Wu, H. H., Chou, H. T., Lin, S. Y., Lai, C. R. & Chen, Y. J., Jan 2025, In: Taiwanese Journal of Obstetrics and Gynecology. 64, 1, p. 76-81 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Genetic variants of IGF2BP2 as potential predictors for perineural invasion of prostate cancer in a Taiwanese population

Weng, W. C., Lin, Y. W., Lai, C. H., Lin, C. Y., Wen, Y. C., Chang, L. C., Yang, S. F. & Chien, M. H., 2025, In: International Journal of Medical Sciences. 22, 6, p. 1269-1277 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Histamine N-methyltransferase (HNMT) as a potential auxiliary biomarker for predicting adaptability to anti-HER2 drug treatment in breast cancer patients

Cheng, T.-C., Hung, M.-C., Wang, L.-H., Tu, S.-H., Wu, C.-H., Yen, Y., Chen, C.-L., Whang-Peng, J., Lee, W.-J., Liao, Y.-C., Lee, Y.-C., Pan, M.-H., Lin, H.-K., Tzeng, H.-E., Guo, P., Chu, C.-Y. & Chen, L.-C., Jan 9 2025, In: Biomarker Research. 13, 1, p. 7

Research output: Contribution to journal › Article › peer-review

Hypoxia enhances IL-8 signaling through inhibiting miR-128-3p expression in glioblastomas

Ho, K. H., Hsu, S. Y., Chen, P. H., Cheng, C. H., Liu, A. J., Chien, M. H. & Chen, K. C., Feb 2025, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1872, 2, 119885.

Research output: Contribution to journal › Article › peer-review

Indoxyl Sulfate Induces Ventricular Arrhythmias Attenuated by Secretoneurin in Right Ventricular Outflow Tract Cardiomyocytes

Hung, Y., Cheng, C. C., Lu, Y. Y., Huang, S. Y., Chen, Y. C., Lin, F. J., Lin, W. S., Kao, Y. H., Lin, Y. K., Chen, S. A. & Chen, Y. J., 2025, (Accepted/In press) In: Cardiovascular Toxicology. e34026.

Research output: Contribution to journal › Article › peer-review

Open Access

Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique

Tran, T. X., Khanh Le, N. Q. & Nguyen, V. N., Mar 2025, In: Computers in Biology and Medicine. 186, 109664.

Research output: Contribution to journal › Article › peer-review

Investigating T Cell Immune Dynamics and IL-6’s Duality in a Microfluidic Lung Tumor Model

Sardarabadi, P., Lee, K. Y., Sun, W. L., Kojabad, A. A. & Liu, C. H., Jan 2025, In: ACS Applied Materials and Interfaces. 17, 3, p. 4354-4367 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Joint effects of temperature and humidity with PM_2.5 on COPD

Tran, H. M., Tsai, F. J., Wang, Y. H., Lee, K. Y., Chang, J. H., Chung, C. L., Tseng, C. H., Su, C. L., Lin, Y. C., Chen, T. T., Chen, K. Y., Ho, S. C., Yang, F. M., Wu, S. M., Chung, K. F., Ho, K. F., Chuang, K. J. & Chuang, H. C., Dec 2025, In: BMC Public Health. 25, 1, 424.

Research output: Contribution to journal › Article › peer-review

Open Access

Mediating role of obstructive sleep apnea in altering slow-wave activity and elevating Alzheimer's disease risk: Pilot study from a northern Taiwan cohort

Tsai, C. Y., Su, C. L., Huang, H. T., Lin, H. W., Lin, J. W., Hei, N. C., Cheng, W. H., Chen, Y. L., Majumdar, A., Kang, J. H., Lee, K. Y., Chen, Z., Lin, Y. C., Wu, C. J., Kuan, Y. C., Lin, Y. T., Hsu, C. R., Lee, H. C. & Liu, W. T., 2025, In: Sleep Health. 11, 1, p. 80-90 11 p.

Research output: Contribution to journal › Article › peer-review

Potential role of solid lipid curcumin particle (SLCP) as estrogen replacement therapy in mitigating TDP-43-related neuropathy in the mouse model of ALS disease

Majumder, P., Hsu, T. I., Hu, C. J., Huang, J. K., Lee, Y. C., Hsieh, Y. C., Ahsan, A. & Huang, C. C., Jan 2025, In: Experimental Neurology. 383, 114999.

Research output: Contribution to journal › Article › peer-review

Open Access

RNA-ModX: a multilabel prediction and interpretation framework for RNA modifications

Yuge, C. C., Hang, E. S., Mamtha, M. R. N., Vishwakarma, S., Wang, S., Wang, C. & Le, N. Q. K., Jan 1 2025, In: Briefings in Bioinformatics. 26, 1, bbae688.

Research output: Contribution to journal › Article › peer-review

Open Access

Sex differences in prognostic factors and genomic variations in oral squamous cell carcinoma: A 5-year retrospective study

Ko, H. H., Wu, F. Y., Chen, Y. S., Lin, W., Fang, C. K., Bai, C. H., Lin, H. Y., Kao, H. F. & Cheng, S. J., 2025, (Accepted/In press) In: Journal of Dental Sciences.

Research output: Contribution to journal › Article › peer-review

Open Access

Small Extracellular Vesicles Engineered Using Click Chemistry to Express Chimeric Antigen Receptors Show Enhanced Efficacy in Acute Liver Failure

Lu, Y. T., Chen, T. Y., Lin, H. H., Chen, Y. W., Lin, Y. X., Le, D., Huang, Y.-H., Wang, A. H. J., Lee, C.-C. & Ling, T. Y., Feb 2025, In: Journal of Extracellular Vesicles. 14, 2, e70044.

Research output: Contribution to journal › Article › peer-review

Open Access

The comparison of serum bone-turnover markers in different stage of chronic kidney disease and the associated impact of intradialytic cycling in patients with end-stage renal disease

Hou, Y. C., Chao, C. T., Shih, L. J., Tsai, K. W., Lin, S. M., Chen, R. M. & Lu, K. C., 2025, In: Aging. 17, 1, p. 217-231 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The expression of BHLHE22 in endometrial carcinoma: Associations with mismatch repair protein expression status, tumor-infiltrating immune cells, programmed death-ligand 1 and clinical outcomes

Chen, L. Y., Chen, H. Y., Lai, H. C., Lin, S. F., Wen, K. C., Darmawi & Liew, P. L., 2025, In: Taiwanese Journal of Obstetrics and Gynecology. 64, 1, p. 110-119 10 p.

Research output: Contribution to journal › Article › peer-review

The off‑target effect of loratadine triggers autophagy‑mediated apoptosis in lung adenocarcinoma cells by deactivating JNK, p38, and STAT3 signaling through both PP2A‑dependent and independent pathways

Chien, M. H., Hung, W. Y., Lai, T. C., Tsai, C. H., Lee, K. L., Hsieh, F. K., Lee, W. J. & Chang, J. H., Apr 2025, In: International Journal of Molecular Medicine. 55, 4

Research output: Contribution to journal › Article › peer-review

The Role of SMAD7 in the Epigenetic Regulation of TGF-β Targets in the Metastasis of Ovarian Cancer

Chen, L. Y., Yang, S. Y., Chou, J. L., Chou, H. L., Yeh, C. C., Chiu, C. C., Lai, H. C., Chan, M. W. Y. & Jhang, J. S., 2025, In: Molecular Carcinogenesis. 64, 2, p. 290-304 15 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Treadmill intervention attenuates motor deficit with 6-OHDA- induced Parkinson's disease rat via changes in lipid profiles in brain and muscle

Panunggal, B., Yeh, T. H., Tsao, S. P., Pan, C. H., Shih, W. T., Lin, Y. T., Faradina, A., Fang, C. L., Huang, H. Y. & Huang, S. Y., 2025, In: Aging. 17, 1, p. 232-250 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Ultrasensitive Assays Detect Different Conformations of Plasma β Amyloids

Li, C. Y., Fan, L. Y., Lin, C. H., Hu, C. J. & Chiu, M. J., Feb 25 2025, In: ACS Omega. 10, 7, p. 7256-7263 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Utilizing a Wireless Radar Framework in Combination With Deep Learning Approaches to Evaluate Obstructive Sleep Apnea Severity in Home-Setting Environments

Lee, K. T., Liu, W. T., Lin, Y. C., Chen, Z., Ho, Y. H., Huang, Y. W., Tsai, Z. L., Hsu, C. W., Yeh, S. M., Lin, H. Y., Majumdar, A., Chen, Y. L., Kuan, Y. C., Lee, K. Y., Feng, P. H., Chen, K. Y., Kang, J. H., Lee, H. C., Ho, S. C. & Tsai, C. Y., 2025, In: Journal of Multidisciplinary Healthcare. 18, p. 381-393 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

10 weeks low intensity treadmill exercise intervention ameliorates motor deficits and sustains muscle mass via decreasing oxidative damage and increasing mitochondria function in a rat model of Parkinson's disease

Tung, Y. T., Liao, Y. C., Yeh, T. H., Tsao, S. P., Chang, C. C., Shih, W. T. & Huang, H. Y., Aug 1 2024, In: Life Sciences. 350, 122733.

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

3D organoid cultivation improves the maturation and functional differentiation of cholangiocytes from human pluripotent stem cells

Budi, N. Y. P., Lai, W. Y., Huang, Y. H. & Ho, H. N., 2024, In: Frontiers in Cell and Developmental Biology. 12, 1361084.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

A bronchiole-on-a-chip and a stretching system for studying human disease model of asthma attack

Sun, C. H., Lee, K. Y., Chan, Y. F., Ho, S. C., Liu, C. Y., Wu, S. M., Sun, W., Ke, Y. T. & Liu, C. H., Oct 1 2024, In: Sensors and Actuators B: Chemical. 416, 136031.

Research output: Contribution to journal › Article › peer-review

A computational predictor for autophagy-related proteins using interpretable machine learning and genetic algorithm

Nguyen, N. T. K., Vo, T. H., Lin, S. H. & Le, N. Q. K., Mar 2024, In: Gene Reports. 34, 101876.

Research output: Contribution to journal › Article › peer-review

Active DNA Demethylase, TET1, Increases Oxidative Phosphorylation and Sensitizes Ovarian Cancer Stem Cells to Mitochondrial Complex I Inhibitor

Chen, L. Y., Shen, Y. A., Chu, L. H., Su, P. H., Wang, H. C., Weng, Y. C., Lin, S. F., Wen, K. C., Liew, P. L. & Lai, H. C., Jun 2024, In: Antioxidants. 13, 6, 735.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Acute invasive fungal rhinosinusitis in post-COVID-19 patients in Vietnam

Quang, L. X., Tam, T. T., Dang, L. H., Chen, Y. C., Hung, S. H., Tai, T. T., Le Vu Hoang, N. & Thanh, N. V., Mar 2024, In: Journal of the Formosan Medical Association. 123, 3, p. 357-365 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Adaptation behaviors modify the effects of body fat on heat-related symptoms among Taiwanese elderly

Chen, C. H., Lin, W. Y., Lee, K. Y., Sun, W. J., Huang, L. Y. & Guo, Y. L. L., Jan 2024, In: International Journal of Hygiene and Environmental Health. 255, 114296.

Research output: Contribution to journal › Article › peer-review

Adenosine monophosphate-regulated protein kinase inhibition modulates electrophysiological characteristics and calcium homeostasis of rabbit right ventricular outflow tract

Lu, Y. Y., Cheng, C. C., Chen, Y. C., Lin, Y. K., Higa, S., Kao, Y. H. & Chen, Y. J., Apr 2024, In: Fundamental and Clinical Pharmacology. 38, 2, p. e12953 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

Adiposity indices and their higher predictive value for new-onset hypertension in metabolically healthy young women: findings from a population-based prospective cohort study

Gumilang, R. A., Fan, Y. C., Wu, S. H. & Bai, C. H., Dec 2024, In: BMC Cardiovascular Disorders. 24, 1, 150.

Research output: Contribution to journal › Article › peer-review

Open Access

Adult PHACE Syndrome Presenting With Visual Field Loss: A Case Report and Review of the Literature

Chen, Y.-T., Liu, Y.-L., Yeh, T.-H., Ho, J.-D., Chang, C.-J. & Hsieh, K.L.-C., Sept 1 2024, In: Journal of Neuro-Ophthalmology. Publish Ahead of Print

Research output: Contribution to journal › Article › peer-review

AIM2 promotes irradiation resistance, migration ability and PD-L1 expression through STAT1/NF-κB activation in oral squamous cell carcinoma

Chiu, H. W., Lee, H. L., Lee, H. H., Lu, H. W., Lin, K. Y. H., Lin, Y. F. & Lin, C. H., Dec 2024, In: Journal of Translational Medicine. 22, 1, 13.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Citations (Scopus)

A new potential therapeutic approach for ALS: A case report with NGS analysis

Hu, C. J., Chen, P. C., Padmanabhan, N., Zahn, A., Ho, C. M., Wang, K. & Yen, Y., Mar 1 2024, In: Medicine (United States). 103, 9, p. E37401

Research output: Contribution to journal › Article › peer-review

Open Access

1 Citation (Scopus)

An expedited model for identifying potential patients with periodic leg movements

Chen, P.-Y., Lin, S.-Y., Wu, C.-S., Hung, S.-H., Chen, D.H.-K., Liu, W.-T. & Lin, Y.-C., Mar 18 2024, (E-pub ahead of print) In: Journal of Sleep Research. p. e14198

Research output: Contribution to journal › Article › peer-review

A novel HDAC8 inhibitor H7E exerts retinoprotective effects against glaucomatous injury via ameliorating aberrant Müller glia activation and oxidative stress

Wu, L. H., Cheng, Y. W., Lin, F. L., Hsu, K. C., Wang, M. H., Yen, J. L., Wang, T. J., Lin, T. E., Liu, Y. C., Huang, W. J. & Hsiao, G., May 2024, In: Biomedicine and Pharmacotherapy. 174, 116538.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Citations (Scopus)

Anti-inflammatory constituents from a sea anemone-derived fungus Arthrinium arundinis MA30

Lee, Y. S., Wu, H. C., Huang, S. J., Hsiao, G., Chi, W. C. & Lee, T. H., Mar 2024, In: Phytochemistry. 219, 113998.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Apoptotic Effect of Simpor Leaf Extract (Dillenia suffruticosa) from Belitung on Colorectal Cancer Cells WiDr

Rahayu, S., Rinendyaputri, R., Nikmah, U. A., Supriyatin, Irnidayanti, Y., Priambodo, R., Nazlihatunnisa, Rusmalina, D. L., Syahira, R. H. & Chang, J., Dec 2024, In: Trends in Sciences. 21, 12, 8316.

Research output: Contribution to journal › Article › peer-review

Open Access

ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells

Chan, T. S., Cheng, L. H., Hsu, C. C., Yang, P. M., Liao, T. Y., Hsieh, H. Y., Lin, P. C., HuangFu, W. C., Chuu, C. P. & Tsai, K. K., 2024, (Accepted/In press) In: Molecular Oncology. 18, 3, p. 562-579 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access