Projects per year
Organisation profile
Organisation profile
Graduate Institute of Pharmacognosy was established in1992. The first chairman was professor Yen Kun-Ying. Through 22 sessions, Institute has been educating over 197 Masters.
The research of Graduate Institute of Pharmacognosy cultivates outstanding professionals for industry, research and professional practice. Our research focuses on isolation and structural chemistry of medical herbs, and the development of Chinese herbs and functional foods for anti-hypertension, anti-hepatitis, anti-hyperglycemia, anti-cancer, and immune regulation. By the cooperation with government and biotechnology industry, pharmacognosy development can fit up with people’s need and government’s policy. In education, the core value is applying pharmacognosy, crude drugs development, and clinical research on Chinese herbal medicine. Students are instructed the ability to research chemical substances and reactivity of Chinese herbal medicine as well as skills for isolating and analyzing the structures of natural products, natural products pharmacology, molecular mechanisms and knowledge associated with applying Chinese herbal medicine to clinical medical needs. After graduation, students seek careers associated with Chinese herbal medicine or biotechnology.
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Collaborations and top research areas from the last five years
Profiles
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Mei-Chuan Chen
- Department of Pharmaceutical Sciences - Professor
- Graduate Institute of Pharmacognosy - Joint-Appointment Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Professor
- Ph. D. Program in the Clinical Drug Development of Herbal Medicine - Joint-Appointment Professor
- TMU Research Center of Thoracic Medicine - Member
Person: Researcher
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Kuo-Hsiang Chuang
- Graduate Institute of Pharmacognosy - Professor
- The Ph.D. Program for Translational Medicine - Joint-Appointment Professor
- Ph.D. Program in Drug Discovery and Development Industry - Joint-Appointment Professor
- Ph. D. Program in the Clinical Drug Development of Herbal Medicine - Joint-Appointment Professor
- Master Program in Clinical Genomics and Proteomics - Joint-Appointment Professor
- TMU Research Center of Drug Discovery - Member
- TMU Research Center of Cancer Translational Medicine - Member
- TMU Research Center of Cell Therapy and Regeneration Medicine - Member
Person: Researcher
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Hsiu-O Ho
- Department of Pharmaceutical Sciences - Professor
- Graduate Institute of Pharmacognosy - Joint-Appointment Professor
- TMU Research Center of Drug Discovery - Member
Person: Researcher
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香砂六君子湯及其相關配伍與西藥併用對CYP酵素影響之共性規律研究(3/3)
Lee, C.-J. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Development of Taiwan Folk Medicine for Osteoporosis Application through the Integration of a Multi-Information Molecular Network and Activity Guidance Model
Lee, M.-H. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
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Studies of Extracts and Purified Compounds from Rhizomes of Alpinia Officinarum Hance on Improving Obesity and Type Two Diabetes Mellitus in Vitro and Animal Models in Vivo
Hou, W.-C. (PI)
8/1/24 → 7/31/25
Project: A - Government Institution › b - National Science and Technology Council
Research output
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2-Hydroxyl hispolon reverses high glucose-induced endothelial progenitor cell dysfunction through the PI3K/Akt/eNOS and AMPK/HO-1 pathways
Wang, T. J., Hou, W. C., Hsiao, B. Y., Lo, T. H., Chen, Y. T., Yang, C. H., Shih, Y. T. & Liu, J. C., 2025, (Accepted/In press) In: British Journal of Pharmacology.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of the Trichodimerol Pathway through Deletion of mcrA in Marine Penicillium rubens YAP001
Shyong, J., Tran Huynh, Q. D., Dziedzic, S., Aguirre, E., Rabot, C., Yuan, B., Herrero-MacKenzie, H. E., Stajich, J. E., Lee, C. K., Kenkel, C. D. & Wang, C. C. C., 2025, (Accepted/In press) In: ACS Chemical Biology. 20, 4, p. 823-829 7 p.Research output: Contribution to journal › Article › peer-review
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Anti-inflammatory and Hepatoprotective Iridoid Glycosides from the Roots of Gomphandra mollis
Tran Huynh, Q. D., Phan, T. T. T., Liu, T. W., Nguyen, T. V., Duong, T. L. T., Hsu, S. J., Chu, M. H., Wang, Y. H., Nguyen Bui, B. T., Nguyen, D. K., Vo, T. H. & Lee, C. K., 2025, (Accepted/In press) In: Journal of Natural Products.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer
Hsieh, C.-M. (Contributor), Chen, L.-C. (Contributor), Liu, D.-Z. (Contributor), Ho, H.-O. (Contributor), Su, C.-Y. (Contributor), Sheu, M.-T. (Contributor), Jhan, H.-J. (Contributor) & Chang, C.-E. (Contributor), Unknown Publisher, 2018
DOI: 10.6084/m9.figshare.5908795, https://doi.org/10.6084%2Fm9.figshare.5908795
Dataset
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Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors
Su, C.-Y. (Contributor), Chen, M. (Contributor), Chen, L.-C. (Contributor), Ho, Y.-S. (Contributor), Ho, H.-O. (Contributor), Lin, S.-Y. (Contributor), Chuang, K.-H. (Contributor) & Sheu, M.-T. (Contributor), Unknown Publisher, May 2 2018
DOI: 10.6084/m9.figshare.6213620.v1, https://tandf.figshare.com/articles/Bispecific_antibodies_anti-mPEG_anti-HER2_for_active_tumor_targeting_of_docetaxel_DTX_-loaded_mPEGylated_nanocarriers_to_enhance_the_chemotherapeutic_efficacy_of_HER2-overexpressing_tumors/6213620/1
Dataset
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A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies
Hsieh, Y.-C. (Creator), Liao, J.-M. (Creator), Chuang, K.-H. (Creator), Ho, K.-W. (Creator), Hong, S.-T. (Creator), Liu, H.-J. (Creator), Huang, B.-C. (Creator), Chen, I.-J. (Creator), Liu, Y.-L. (Creator), Wang, J.-Y. (Creator), Tsai, H.-L. (Creator), Su, Y.-C. (Creator), Wang, Y.-T. (Creator) & Cheng, T.-L. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5819661.v1, https://springernature.figshare.com/collections/A_universal_in_silico_V_D_J_recombination_strategy_for_developing_humanized_monoclonal_antibodies/5819661/1
Dataset