Graduate Institute of Clinical Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2024

• 18 Active
• 416 Finished

Projects per year

Search results

• Active

  自體免疫心肌炎引起心室心律不整及鈣離子調控失衡、粒線體異常與NLRP3/MIF發炎體訊息路徑活化之致病機轉及治療策略探討(3/3)

  Chen, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討甲基乙二醛經SREBP-1/GPX4促進腎小管細胞鐵依賴型死亡敏感性導致脂毒性的機制以及菸鹼胺磷酸核糖轉基酶NAD+介入治療之可行性

  Peng, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Nav1.5 deficiency 致心肌纖維化機轉以及開發外泌體攜帶miRNA作為新治療策略(1/2)

  Kao, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• FGF9在急性腎損傷與發展至慢性腎臟病進程之角色探討(3/3)

  Cheng, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討塑膠顆粒影響腎臟細胞的微環境：聚焦胞外體、虛擬篩選天然物平台和塑膠顆粒生物分解方法

  Chiu, H.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討ENO1調控PD-L1表現與影響肺癌免疫抑制治療之機制(1/3)

  Chou, T.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 開發以外泌體為基礎之急性呼吸窘迫症候群創新診斷與治療平台－急性呼吸窘迫症候群所致肺損傷及肺纖維化: 以外泌體為診斷基礎暨以工程化外泌體為治療基礎之創新開發(1/3)

  Huang, C.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 拯救化學治療誘發之癌症成纖維細胞表基因變化為進展性胰臟腺癌新穎治療手段(2/3)

  Tsai, K. K.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討第一型組織胺受體在頭頸鱗狀細胞癌惡性進程之角色扮演及成為治療標靶之潛力

  Chien, M.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 結合真實世界臨床數據與人體生物資料庫探討腫瘤微環境對膀胱癌預後的影響

  Wang, Y.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 膀胱癌是否能經由Glo1-NAMPT-SIRT1路徑影響氧化壓力及生物能量來調控PD-L1並靶向克服免疫逃避機制(1/3)

  Chen, K.

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 112年度科研創業計畫：突破性原發與轉移性肝癌樞紐基因標靶脂肪奈米微粒微小RNA療法

  Tsai, K. K.

  7/1/23 → 6/30/24

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Putri, D. U.

  5/1/23 → 4/30/24

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 新聘教師研究補助

  Chou, T.

  5/1/23 → 4/30/24

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 探討醣蛋白ESM1在腸胃道癌症進程之角色及相關調控機制

  Chien, M.

  1/1/23 → 12/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 建置病人來源類組織庫作為癌症標靶與藥物開發之人類化身平臺

  Tsai, K. K.

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 胸部惡性腫瘤的空間基因體學：肺腺癌、食道鱗狀細胞癌和胸腺瘤的腫瘤微環境

  Chou, T.

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 客製化外泌體miRNA應用於急性與慢性呼吸道疾病之精準治療

  Huang, C.

  1/1/23 → 12/31/23

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Finished

  Rescuing Chemotherapy-Induced Epigenetic Alterations in Cancer Fibroblasts as a Novel Therapeutic Strategy in Advanced Pancreatic Ductal Adenocarcinoma (1/3)

  Tsai, K. K.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Fgf9 in Acute Kidney Injury and Progression to Chronic Kidney Disease (2/3)

  Cheng, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Calcium Dysregulation, Mitochondrial Disorder, and Inflammasome Signaling of Nlr Family Pyrin Domain Containing 3 (Nlrp3) /Macrophage Migration Inhibitory Factor (Mif) in Autoimmune Myocarditis-Induced Ventricular Arrhythmogenesis

  Chen, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 去勢抗性前列腺癌經Snail調控Hexokinase,Phosphofructokinase,Pyruvate kinase影響上皮間質轉化促侵襲性探討-以代謝酶調節劑合併Enalutamide之評估

  Peng, C.

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Integrated Proteomic,Genetic,Small-Molecule, and Functional Screening of Novel and Targetable Invadopodial Regulators in Stem-Like Cancer Cells: Focusing on Cell-Surface Amfr as a Prioritized Therapeutic Target in Invasive Gastroenterological Cancers( III )

  Tsai, K. K.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 探討O-GlcNAc轉移酶調控肺腺癌免疫抑制治療生物預測標記PD-L1與腫瘤突變負荷量之機制(3/3)

  Chou, T.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of the Diagnostic and Therapeutic Value to Novel Ferroptotic Biomarkers in Double Hit Lymphoma( I )

  Chao, T.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Therapeutic Potential of Regulation of Prostaglandin E2 Receptor and Autophagy by Endothelin-Converting Enzyme Inhibition in Chronic Kidney Disease( III )

  Chiu, H.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Microplastics and Nanoplastics Exposure Induce Autophagy and Upregulate Srebps in Kidneys and Cause Endothelial Leakiness in Blood Vessels

  Chiu, H.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of the Role Kh-Type Splicing Regulatory Protein (Khsrp) in the Progression of Renal Cell Carcinoma

  Chien, M.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Il-33/St2 Signaling on Atrial and Pulmonary Vein Arrhythmogenesis from Dysregulated Calcium Homeostasis, Endoplasmic Reticulum Stress, and Mitochondria Bio-Function: Pathogenesis and Therapeutic Strategy for Atrial Fibrillation

  Chen, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Effects of Nanoparticle Mediated Controlled Deliveries of Mesenchymal Stem Cells-Derived Exosomes, Cytokine Binding Decoy Peptide and Caveolin-1 Scaffolding Domain Peptide against Obesity with Sepsis: Focusing on Cell Death Process-Related Mechanisms (2/2)

  Huang, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 利用Iodoacetamide衍生物找尋與鑑定新型藥物標靶用於治療多型性神經膠質母細胞瘤

  Lin, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 2-1-3 精進核心研究服務平台-研究型主治醫師蔡坤志

  Tsai, K. K.

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 精準醫學臨床模組開發_開發可預測結核病患者治療反應和疾病進展的血清標記蛋白

  Putri, D. U.

  1/1/22 → 12/31/22

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 糖尿病所致慢性腎臟病變發展:尿液暨血液外泌體多體學分析與創新生物標記開發

  Huang, C.

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 間質幹細胞療法治療 COVID-19引起的急性呼吸窘迫綜合症的個人化監測

  Putri, D. U.

  1/1/22 → 12/31/22

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• Metronomic Chemotherapy Potentiates Immuno-Surveillance and Immunotherapy in Desmoplastic Pancreatic Cancer: Focusing on the Roles of Tumor Stroma and Myeloid-Derived Suppressor Cells( III )

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Calcium Dysregulation, Mitochondrial Disorder, and Inflammasome Signaling of Nlr Family Pyrin Domain Containing 3 (Nlrp3) /Macrophage Migration Inhibitory Factor (Mif) in Autoimmune Myocarditis-Induced Ventricular Arrhythmogenesis

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Therapeutic Potential of Regulation of Prostaglandin E2 Receptor and Autophagy by Endothelin-Converting Enzyme Inhibition in Chronic Kidney Disease( II )

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Spike S1 Protein of Sars-Cov-2-Mediated Electrical and Structural Remodeling as a Novel Therapeutic Strategy

  Kao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Aspm-Par-Pcp Signaling in Invasive-Cancer-Stem-Cell-Mediated Metastasis and Its Therapeutic Targeting

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Integrated Proteomic,Genetic,Small-Molecule, and Functional Screening of Novel and Targetable Invadopodial Regulators in Stem-Like Cancer Cells: Focusing on Cell-Surface Amfr as a Prioritized Therapeutic Target in Invasive Gastroenterological Cancers( II )

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Role of Btk/Her2 Signaling as a Therapeutic Target for Restoration of T Cell Function and Reversal of Trastuzumab Resistance in Her2+ Breast Cancer

  Chao, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of the Role Kh-Type Splicing Regulatory Protein (Khsrp) in the Progression of Renal Cell Carcinoma

  Chien, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting Il-33/St2 Signaling on Atrial and Pulmonary Vein Arrhythmogenesis from Dysregulated Calcium Homeostasis, Endoplasmic Reticulum Stress, and Mitochondria Bio-Function: Pathogenesis and Therapeutic Strategy for Atrial Fibrillation

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Microplastics and Nanoplastics Exposure Induce Autophagy and Upregulate Srebps in Kidneys and Cause Endothelial Leakiness in Blood Vessels

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Utilizing Artificial Intelligence Vi Rtual Screening Platform to Identify a Small-Molecule Inhibitor of Dna Polymerase Theta and Estimating Its Therapeutic Effectiveness on Metastatic Castration-Resistant Prostate Cancer

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Microplastics and Nanoplastics Exposure Induce Autophagy and Upregulate Srebps in Kidneys and Cause Endothelial Leakiness in Blood Vessels

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Fgf9 in Acute Kidney Injury and Progression to Chronic Kidney Disease

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of the Role and Molecular Mechanism of Granulocyte-Colony Stimulating Factor in Bladder Tumor Microenvironment

  Wang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Effects of Nanoparticle Mediated Controlled Deliveries of Mesenchymal Stem Cells-Derived Exosomes, Cytokine Binding Decoy Peptide and Caveolin-1 Scaffolding Domain Peptide against Obesity with Sepsis: Focusing on Cell Death Process-Related Mechanisms

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council