Department of Physiology

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2019 2020 2021 2022 2023

• 7 Active
• 121 Finished

Projects per year

Search results

• Active

  辛伐他汀透過活化LKB1和ROS/AMPK的機制達到抗腎細胞癌的作用，與結合抑制代謝途徑藥物的協同作用

  Juan, S.

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Explore the Pathophysiology Role of Vascular Endothelial Cell and Adam 17 during Blue Light-Induced Retinopathy, and the Therapeutic Strategy.

  Li, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting the Adipokines/Batokines Secreted from Afferent Renal Artery Adipocyte Tissue to Explore the Obesity Induced Diabetic Renal Pathophysiology Role under Atf3 Regulation and the Basic and Clinical Therapeutic Application. (1/3)

  Lin, H.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明SCUBE蛋白家族對血栓形成與心臟修復之分子機制(2/3)

  Lin, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Telekaryophagy, an Novel Entire Nucleus Elimination Programme in the Liver and Mammary Gland: Exploring Its Role in Genomic Stability and Physiopathology (2/3)

  Chao, H.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 英明格抑制肺張力接受器機轉之探討

  Lin, Y.

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Ahr Defect Changes Integrin Signaling in Retinal Pigment Epithelial Cells, Resulting Retinal Inflammation and Function Impairment( III )

  Li, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology
• Finished

  探討組織蛋白去乙醯酶異構酵素參與視網膜微血管新生和血視網膜屏障滲漏之訊息路徑

  Li, C.

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Metformin抑制TRPA1與P2X3受器所引發的呼吸反射及過度敏感之機制探討

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展一新型藥物作為改善肥胖及肥胖引發糖尿病導致腎病變症候群之轉譯醫學研究(3/3)

  Lin, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討藍光誘發視網膜病變中血管內皮細胞與去整合素金屬蛋白?17的病生理角色及治療策略

  Li, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芳香烴受體於眼科疾病之治療潛力機制探討-多環芳香烴受體缺陷改變視網膜色素上皮細胞的整合素訊息,促進視網膜發炎環境及損害視網膜功能之分子機轉(2/3)

  Li, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Telekaryophagy，一種在肝臟和乳腺中新發現的全核消除程序：探索其在基因組穩定性和生理病理學中的作用(1/3)

  Chao, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 長期尿道出口阻塞透過膠原蛋白 I 沉積而降低膀胱順應性-針灸治療的潛在標的

  Lin, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 辛伐他汀抗腎細胞癌的作用，經由抑制代謝重編程從mTOR、PPAR到RhoA(3/3)

  Juan, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 真菌天然物奈米劑型應用於藍光誘發之視網膜血管病變機制及其治療

  Li, C.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 結合人工智慧與穿戴式裝置之不良姿勢矯正系統-II

  Chen, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展一新型藥物作為改善肥胖及肥胖引發糖尿病導致腎病變症候群之轉譯醫學研究(2/3)

  Lin, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討生物時鐘所調控之新型態肝細胞分裂模式在肝臟生理功能及相關疾病中所扮演之角色(3/3)

  Chao, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 英明格引發呼吸道過度敏感:肺C纖維的角色(3/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 辛伐他汀抗腎細胞癌的作用，經由抑制代謝重編程從mTOR、PPAR到RhoA(2/3)

  Juan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討多環芳香烴受體缺陷重啟多能細胞特性之新穎路徑與應用

  Li, C.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芳香烴受體於眼科疾病之治療潛力機制探討-多環芳香烴受體缺陷改變視網膜色素上皮細胞的整合素訊息,促進視網膜發炎環境及損害視網膜功能之分子機轉(1/3)

  Li, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用重心量測技術之病人離床監控系統開發

  Chen, H.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 109年度「中藥材作為食品原料之安全性評估」

  Li, C.

  6/4/20 → 12/4/20

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 開發具壓電特性用於骨再生的生物陶瓷

  Chen, H.

  1/1/20 → 12/31/20

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 真菌天然物奈米劑型應用於藍光誘發之視網膜血管病變機制及其治療

  Li, C.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Development of High-Quality Esport Seats Using Anti-Bedsore and Physiological Monitoring Techniques

  Chen, H.

  11/1/19 → 10/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ergonomics 100%
  • Seats 99%
  • Headphones 67%
  • Industry 62%
  • Motion analysis 55%

• Efficacy of Simvastatin in Renal Cell Carcinoma by Restraining Metabolic Reprogramming from Mtor, Ppar to Rhoa(1/3)

  Juan, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of a New Drug as a Translational Medical Study to Improve the Obesity and Obesity-Induced Diabetes Nephropathy Syndrome

  Lin, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification a Novel Circadian Clock-Mediated Cell Dividing in Hepatocyte: Mechanistic Exploration for Physiological and Pathological Functions in Liver(2/3)

  Chao, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Sumatriptan Induces Airway Hypersensitivity: Role of Lung C Fibers(2/3)

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Auricle Electroacupuncture Protect Cardiac Function through Potentiating Vagal Tone

  Lin, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結直腸誘導之刺激訊號透過頻譜分析建立大鼠內臟疼痛模型

  Lin, T.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 具生物降解、生物相容及骨傳導性之鎂基干涉螺釘應用於前十字韌帶重建-鎂基金屬玻璃合金干涉螺絲在前十字韌帶固定應用之設計與生物力學評估

  Chen, H.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Identification a Novel Circadian Clock-Mediated Cell Dividing in Hepatocyte: Mechanistic Exploration for Physiological and Pathological Functions in Liver(I)

  Chao, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Moxibustion at Bl-25 Attenuated Stress-Sensitized Colon-Bladder Crosstalk by Thermal Effect Impacting Heat Shock Protein 90-Cochaperone Dynamics of Glucocorticoid Receptor

  Lin, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • HSP90 Heat-Shock Proteins 100%
  • Glucocorticoid Receptors 96%
  • Tacrolimus Binding Proteins 95%
  • Moxibustion 91%
  • Colon 52%

• Sumatriptan Induces Airway Hypersensitivity: Role of Lung C Fibers

  Lin, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• An Artificial Inteligence System with Wearable Devices for Correction of Inadequate Posture

  Chen, H.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Artificial intelligence 100%
  • Wearable sensors 94%
  • Sensors 58%
  • Oxygen sensors 54%
  • Online systems 46%

• Mechanisms and Functional Roles of Orexins’Cardiovascular Effects in the Dorsomedial Hypothalamus

  Hwang, L.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hypothalamus 100%
  • Orexins 78%
  • Neurons 16%
  • Sodium-Calcium Exchanger 10%
  • Neural Pathways 8%

• Mechanistic Studies of Renal Cell Carcinoma: from Rhoa-Mediated Expression of Cd44-Targeting Micrornas to the Development of Biomarkers and Therapies

  Juan, S.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Cell Carcinoma 100%
  • MicroRNAs 67%
  • Biomarkers 15%
  • Simvastatin 14%
  • Epithelial Cells 13%

• The role of abscission failure in the formation of hepatocellular carcinoma.

  Chao, H.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification a Novel Cell Dividing Type of Hepatocyte and Exploring Its Physiopathological Function.

  Chao, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hepatocytes 100%
  • abscission 89%
  • cytokinesis 76%
  • liver 32%
  • liver failure 29%

• Activation of Adenosine A3 Receptors Suppresses Airway Hypersensitivity: Role of Pulmonary C-Fiber Afferents

  Lin, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adenosine A3 Receptor Agonists 100%
  • Adenosine A3 Receptors 54%
  • Unmyelinated Nerve Fibers 50%
  • Hypersensitivity 46%
  • Lung 36%

• Risk Evaluation of Soccer Players’ Brain Injuries Induced by Repeated Head Impact

  Chen, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Football 100%
  • Brain 40%
  • Gait analysis 13%
  • Biomarkers 12%
  • Motion control 10%

• Estrogen Affects the Colon-Urethra Crosstalk via Spinal Kalirin/Psd-95-Nr2b-Dependent Nr2b Phosphorylation in Rats

  Lin, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • urethra 100%
  • colon 58%
  • estrogens 48%
  • mustard oil 48%
  • pain 27%

• Electroacupunture Relieves Pelvic Pain by Antagonizing Mecp2-Dependent Epigenic Modification of Bdnf Mediates Estrogen-Fasciliated Uterus-Colon Crosstalk in Rats

  Lin, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methyl-CpG-Binding Protein 2 100%
  • Urethra 61%
  • Brain-Derived Neurotrophic Factor 59%
  • Colon 49%
  • Histones 39%

• Study on the Mechanism Involved in Nanoparticles-Induced Tight Junction and Aquaporins Damages in Endothelial Cells, as Well as the Effects on Physiological Function of Endothelial Barriers

  Li, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanoparticles 100%
  • Blood-Brain Barrier 69%
  • Aquaporins 65%
  • Tight Junction Proteins 39%
  • Permeability 35%

• Mechanistic Studies of Renal Cell Carcinoma: from Rhoa-Mediated Expression of Cd44-Targeting Micrornas to the Development of Biomarkers and Therapies

  Juan, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Cell Carcinoma 100%
  • MicroRNAs 67%
  • Biomarkers 15%
  • Simvastatin 14%
  • Epithelial Cells 13%

• 可攜式急性腎臟損傷 (AKI)及顯影劑腎病變(CIN)尿液微型核醣核酸的非侵入式檢測系統之發展及開發單一化學藥物治療AKI及CIN所造成之腎損傷(1/3)

  Lin, H.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology