Department of Pharmacology

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 182 Finished

Projects per year

Search results

• Finished

• 探討PRDX5對於創傷性腦損傷後慢性的焦慮行為之重要性(1/3)

  Yang, C. H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討具調節STAT訊息之真菌成分在視網膜穆勒及小神經膠細胞作用機制及其改善青光眼誘發神經性退化之療效(3/3)

  Hsiao, G. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 天然物抑制血管新生及相關癌症之治療潛力與分子作用機轉探討

  Huang, S.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎香豆素結構天然植物萃取物於抗血管新生、抗淋巴管新生以及抗發炎之藥理活性評估與機轉探討(3/3)

  Hsu, M.-J. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 探討治療視網膜之中藥成分對視網膜穆勒細胞活化與非高眼壓型青光眼之療效作用機制

  Hsiao, G. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 蓮子心生物鹼對於兒童神經膠母細胞瘤影響細胞凋亡以及上皮-間質轉化之機轉探討

  Chen, C.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting the Perineuronal Nets for Amelioration of Aberrant Exaggerated Fear Associations to Ambiguous Cues Associated to Early-Life Social Isolation( III )

  Yang, C. H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Application of Novel Natural Naphthoquinone-Based Derivatives as Anti-Angiogenic, Anti-Lymphogenic and Anti-Tumor Agents and Its Underlying Mechanisms

  Huang, S.-W. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Therapeutic Potential and Molecular Mechanism of Natural Products in Pediatric High-Grade Gliomas (2/3)

  Chen, C.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Retinoprotective Role of Aryl Hydrocarbon Receptor Activation in Glaucomatous Progression( III )

  Hsiao, G. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Mechanism of Paclitaxel Involved in the Regulation of Platelet Activation, Apoptosis and Autophagy: in Vivo and in Vitro Study

  Lu, W.-J. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• To Evaluate the Pharmacological Mechanisms of Novel Natural Plant Extracts of Coumarins in Suppressing Angiogenesis, Lymphangiogenesis and Inflammation (2/3)

  Hsu, M.-J. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Investigation of Fungal Stat-Regulating Compounds on Retinal Müller and Microglial Functions and Their Therapeutic Profiles in Glaucomatous Neurodegeneration (2/3)

  Hsiao, G. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 探討木香萃取物預防血小板活化和血栓形成之作用

  Lu, W.-J. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• 銀杏素改善自體血栓栓塞性腦中風引起微小神經膠細胞和神經元活化的神經再生作用

  Hsieh, C.-Y. (PI)

  3/1/22 → 2/28/23

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• Active

  探討SHANK3與其相關訊息傳遞蛋白: RBFA, TRIM5, and GPR68影響缺血性中風之分子機制

  Yang, C. H. (PI)

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Finished

• The Investigation of Fungal Stat-Regulating Compounds on Retinal Müller and Microglial Functions and Their Therapeutic Profiles in Glaucomatous Neurodegeneration

  Hsiao, G. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Impact of Chronic Sleep Deprivation on Neurocognition and Mood Regulation among Adolescents: Focus on Behavioral and Neuroendocrine Alterations in Rodents( III )

  Yang, C. H. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 藉由調控神經包網結構來改善早期社交孤立所誘發於模棱兩可的資訊下異常恐懼記憶連結的形成(2/3)

  Yang, C. H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigate the New Therapeutic Strategy of Hinokitiol in Hepatic Ischemia/Reperfusion Injury( III )

  Lu, W.-J. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Investigating the Therapeutic Potential and Molecular Mechanism of Natural Products in Pediatric High-Grade Gliomas

  Chen, C.-H. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• A Breakthrough Therapeutic Strategy against Ischemic Brain Injury- the Senolytic Treatment Dramatically Expands Therapeutic Time Window of Acute Ischemic Stroke

  Hsieh, C.-Y. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Retinoprotective Role of Aryl Hydrocarbon Receptor Activation in Glaucomatous Progression( II )

  Hsiao, G. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Mechanism of Paclitaxel Involved in the Regulation of Platelet Activation, Apoptosis and Autophagy: in Vivo and in Vitro Study

  Lu, W.-J. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Develop the Novel Small Molecular Inhibitor to Target Angiogenesis and the Tumor Microenvironment for Primary and Recurrent Gbm Patient( III )

  Huang, S.-W. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討新穎小分子化合物影響三陰性乳癌細胞免疫檢查點之機制

  Huang, S.-W. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 透過in silico virtual docking從現有藥物中篩選干擾 Spike protein 及 ACE2 結合之治療COVID-19潛力藥物

  Yang, C. H. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 從FDA核可藥庫篩選可誘發TMPRSS2降解之COVID-19潛力治療藥物研究

  Yang, C. H. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討真菌天然物成分HMH-1-80-3抑制小神經膠質細胞之活化機制及對內毒素誘發腦部發炎之療效評估

  Hsiao, G. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• Esculetin對改善周邊血管平滑肌細胞增生及大腦血管內皮細胞發炎反應的活性評估及機轉探討

  Hsieh, C.-Y. (PI)

  3/1/21 → 2/28/22

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 探討GLO1 改善缺血性腦中風伴隨的羰基壓力及促進大腦功能性恢復的機制

  Yang, C. H. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 利用蛋白質體學研究方式探討glyoxalase 1改善急性缺血性腦中風造成血腦障壁傷害之作用機制

  Hsieh, C.-Y. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Mechanism of Paclitaxel Involved in the Regulation of Platelet Activation, Apoptosis and Autophagy: in Vivo and in Vitro Study

  Lu, W.-J. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Using Transcriptomic and Proteomic Approaches to Investigate the Molecular Mechanisms of Platinum-Resistance in Bladder Cancer and Develop New Therapeutic Strategies

  Chen, C.-H. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Develop the Novel Small Molecular Inhibitor to Target Angiogenesis and the Tumor Microenvironment for Primary and Recurrent Gbm Patient( II )

  Huang, S.-W. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• The Retinoprotective Role of Aryl Hydrocarbon Receptor Activation in Glaucomatous Progression( I )

  Hsiao, G. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Study of Shank3, a Synaptic Scaffolding Protein, Modulated Neuroinflammation in the Pathology of Acute Ischemic Stroke

  Hsieh, C.-Y. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Targeting the Perineuronal Nets for Amelioration of Aberrant Exaggerated Fear Associations to Ambiguous Cues Associated to Early-Life Social Isolation( I )

  Yang, C. H. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• The Impact of Chronic Sleep Deprivation on Neurocognition and Mood Regulation among Adolescents: Focus on Behavioral and Neuroendocrine Alterations in Rodents( II )

  Yang, C. H. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 新穎性苯並咪唑衍生物MFB之抗多型性神經膠質母細胞瘤之藥理活性評估與機轉探討

  Huang, S.-W. (PI)

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - National Science and Technology Council