Department of Pediatrics

Projects

Projects per year 2010 2012 2013 2014 2016 2017 2018 2019 2020 2021 2022 2023 2026

• 4 Active
• 94 Finished

Projects per year

Search results

• Active

  Maternal Diesel Exhaust Particle Exposure Impairs Lung Development by Modulating Gut Microbiota in Neonatal Rats

  Chen, C.-M. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

• In Vitro Screening and Investigation of the Potent Probiotic Strains and Their Synergism with Antibiotics for Inhibiting Antibiotic-Resistant Nontyphoidal Salmonella

  Fang, S.-B. (PI)

  8/1/24 → 7/31/26

  Project: A - Government Institution › b - National Science and Technology Council

• Precision Medicine: Establish the Patient-Derived Genetic Model for Ryanodine Receptor 1-Related Myopathy in Zebrafish and Human Cell Line

  Kuo, Y.-T. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council

  • Zebra Fish 100%
  • Ryanodine Receptor 1 100%
  • Genetic Model 100%
  • Genetic Mechanism 50%

• Evaluating the Therapeutic Effects of Photobiomodulation Therapy on Adhd Model Rat

  Chang, H. (PI)

  8/1/24 → 7/31/25

  Project: A - Government Institution › b - National Science and Technology Council
• Finished

  探討微生物群在子宮內生長遲緩大鼠和早產兒肺發育的角色(2/2)

  Chen, C.-M. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以全基因組剔除(GeCKO)分析模式探討人類瀰漫性大B細胞淋巴瘤(DLBCL)新穎標靶抗癌有效性分析

  Chen, S.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 台灣家族特有肌聯蛋白單核苷酸位點變異導致肌失養症之病因學研究(III)(2/2)

  Kuo, Y.-T. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以外泌體介導CAR-T免疫細胞療法發展新穎性瀰漫性大B細胞淋巴癌抗癌模式

  Chen, S.-H. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 112年度產學合作計畫「以反轉基因法建立諾羅病毒抑制報導系統 (II)」

  Chen, S.-Y. (PI)

  6/1/23 → 5/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 研究Notch-Hes1 訊息在子宮內生長遲滯的大鼠肺臟發育的角色

  Chen, C.-M. (PI)

  1/1/23 → 12/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 萘醌咪唑小分子改造化合物對頭孢曲松抗藥性非傷寒沙門氏桿菌之抗菌作用與機轉

  Fang, S.-B. (PI)

  1/1/23 → 12/31/23

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Investigation on the Pathogenicity of a Novel Ttn Singlenucleotide Variation in a Taiwanese Familial Titinopathy (Iii) (1/2)

  Kuo, Y.-T. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Development of Human Diffuse Large B-Cell Lymphoma Targeted Therapy through Genome-Wide Crispr Screening Library Platform

  Chen, S.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 針對非傷寒沙門氏菌抗生素抗藥性以人工智慧輔助開發創新型診斷工具及整合探討基因機轉：從全基因體定序篩選多重基因組合到去氧核醣核酸指紋

  Fang, S.-B. (PI)

  8/1/22 → 7/31/23

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Research on the Role of Microbiota in Lung Development of Intrauterine Growth Restricted Rats and Preterm Infants

  Chen, C.-M. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 快速偵測具carbapenem抗藥性之綠膿桿菌: 一個透過機器學習方法以MALDI- TOF光譜資料預測抗生素敏感試驗結果的跨領域研究

  Lin, H.-C. (PI)

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - National Science and Technology Council

• Human Norovirus Reverse Genetics-Based Inhibitory Reporter System

  Chen, S.-Y. (PI)

  6/1/22 → 5/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 將近紅外線光能量轉換至熱能量後對骨骼肌再生影響之研究

  Chang, H. (PI)

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 解譯組蛋白脫乙醯酶抑制劑在圓細胞肉瘤的角色

  Liu, Y.-L. (PI)

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Exploring the Probiotic Effects and Mechanisms on Hyperoxia-Induced Lung Injury in Neonatal Mice

  Chen, C.-M. (PI)

  11/1/21 → 10/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Chen, S.-Y. (PI)

  9/15/21 → 9/14/22

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Improved Palmitate-Induced-Insulin Resistance by Recover Mitoferrin Function via Decreased of Hif-1α Expression

  Kuo, Y.-T. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Development of Precision Myc/Bcl2/Bcl6 Targeted Therapy on Human B-Cell Lymphoma through Crispr/Cas9 Gene Editing Platform

  Chen, S.-H. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Postbiotics and Probiotics Attenuate Hyperoxia-Induced Lung Injury through Suppression of Inflammation and Modulation of Immunity in Neonatal Mice

  Chen, C.-M. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation on the Pathogenicity of a Novel Ttn Singlenucleotide Variation in a Taiwanese Familial Titinopathy (Ii)

  Kuo, Y.-T. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Characterization of Yqic for Developing Targeted Antibiotics and Genetic Analysis of Salmonella Antibiotic Resistance and Invasiveness: a Two-Way Approach to Novel Strategies against Salmonellosis

  Fang, S.-B. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 抗Tn單株抗體透過抑制氧化應激和炎症反應減輕新生仔鼠高氧誘導的腎臟損傷

  Chen, C.-M. (PI)

  3/1/21 → 2/28/22

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 應用循環腫瘤細胞預測標靶藥物對復發性、難治性、高危險群兒科腫瘤的治療反應

  Liu, Y.-L. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 人工智慧輔助發展抗藥性非傷寒沙門氏菌之創新型診斷工具及探討沙門氏菌與定植和抗生素反應相關之基因

  Fang, S.-B. (PI)

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Characterization of Yqic for Developing Targeted Antibiotics and Genetic Analysis of Salmonella Antibiotic Resistance and Invasiveness: a Two-Way Approach to Novel Strategies against Salmonellosis

  Fang, S.-B. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 台灣家族特有肌聯蛋白單酶酸位點變異導致肌失養症之病因學研究

  Kuo, Y.-T. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Hyperoxia-Induced Lung Injury Is Mediated by the Lung and Gut Microbiome in Newborn Mice

  Chen, C.-M. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Using an Ex Vivo Circulating Tumor Cell Expansion System to Develop Precision Medicine Approaches for Pediatric Neural Tumors

  Liu, Y.-L. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 周產期尼古丁暴露對小鼠後代肺發育的影響

  Chen, C.-M. (PI)

  3/1/20 → 2/1/21

  Project: C - Project of Alliance › n - Yuan's General Hospital

• Artificial intelligence-assisted development of innovative diagnostics for antibiotic-resistant non-typhoidal Salmonella and investigation of Salmonella genes associated with colonization and antibiotic response

  Fang, S.-B. (PI)

  1/1/20 → 12/31/20

  Project: A - Government Institution › d - Ministry of Education

• 應用循環腫瘤細胞預測標靶藥物對復發性、難治性、高危險群兒科腫瘤的治療反應

  Liu, Y.-L. (PI)

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 探討胸腺基質淋巴生成素接受器在氣喘兒童白血球免疫表型的表現

  Lin, S.-C. (PI)

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Characterization of YqiC for developing targeted antibiotics and genetic analysis of Salmonella antibiotic resistance and invasiveness: a two-way approach to novel strategies against salmonellosis (1/3)

  Fang, S.-B. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Development of Leukemia Based Precision Medicine Research Model on Non-Invasive Apoptosis Detection Platform – Application of Crispr/Cas9 Gene and Target Therapy on Philadelphia Chromosome of Chronic Myelogenous Leukemia as an Example

  Chen, S.-H. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

  • Leukemia 100%
  • Programmed Cell Death 100%
  • Chronic Myelogenous Leukemia 100%
  • Personalized Medicine 100%
  • Cas9 100%

• Investigation of Effects and Mechanisms of Tn Immunization on Hyperoxia-Induced Lung Injury in Neonatal Rats(2/2)

  Chen, C.-M. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Impact of Chromatin-Modifying Agents on the Tumor Differentiation and Mibg Uptake of Neuroblastoma

  Liu, Y.-L. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Cathelicidin通過抑制氧化應激減輕新生仔鼠高氧誘導的肺損傷

  Chen, C.-M. (PI)

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• Developing novel strategies for combating antibiotic-resistant Salmonella. Subproject: Identification of inhibitors for intracellular ceftriaxone-resistant Salmonella as novel antibiotics and whole transcriptome RNA sequencing for global gene regulation by yqiC in Salmonella

  Fang, S.-B. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 氣喘兒童胸腺基質淋巴生成素接受器在周邊血球免疫表型的監測

  Lin, S.-C. (PI)

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• The Severity Model of Brain Damage: Examining the Blood-Brain Early Injurious and Protective Biomarker Panels That Relate to the Susceptibility and Tolerance Responses of Hypoxic Ischemia(II)(2/3)

  Huang, C.-C. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• Molecular Biomarkers Targeting the Metastatic Relapse of Neuroblastoma

  Liu, Y.-L. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Ganglioneuroblastoma 100%
  • Biological Marker 100%
  • Neuroblastoma 100%
  • Neoplasm 16%
  • Minimal Residual Disease 16%

• Investigation of novel genetic mutations for antibiotic resistance, intracellular upregulated Salmonella genes within host cells, and the mechanisms of yqiC-induced host innate immunity for combating Salmonella infection (3/3)

  Fang, S.-B. (PI)

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Gene Mutation 100%
  • Host Cell 100%
  • Innate Immune System 100%
  • Salmonella 100%
  • Antimicrobial Resistance 100%

• Restoration of Mitochondrial Function: in Search of Therapeutic Agents for Metabolic Myopathy

  Kuo, Y.-T. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Mitochondrial Biogenesis 100%
  • Muscle Disorder 100%
  • Mitochondrial Function 100%
  • Mitochondrial Myopathy 50%
  • Extracellular Flux 50%

• Investigation of Effects and Mechanisms of Tn Immunization on Hyperoxia-Induced Lung Injury in Neonatal Rats

  Chen, C.-M. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• 新聘教師研究補助

  Kuo, Y.-T. (PI)

  1/1/18 → 12/31/18

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty