College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 245 Active
• 3059 Finished

Projects per year

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• b - Ministry of Science and Technology

  結核菌感染臨床免疫組庫建立:探勘免疫球蛋白於結核菌感染之保護機制與臨床轉譯應用(3/3)

  Tsai, I.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Sumoylation of Histone Deacetylase 2 Contributes to CTGF Expression and Pulmonary Fibrosis in Chronic Obstructive Asthma (III)

  Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on the Mechanism of Cross-Talk between Ahr and Autophagy, and Autophagy---Associated Physiological or Pathological Phenomenon on Vascular and Airway Systems (I)

  Li, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Autophagy 88%
  • Benzo(a)pyrene 17%
  • Fibrosis 15%
  • Endothelial Cells 15%

• The Study of Apoptosis, Inflammation, Autophagy and Organ Functions in Rat Liver Following Hemorrhagic Shock and Protective Mechanism of Ligustrazine.

  Chen, R. & Wang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Reperfusion Injury 100%
  • tetramethylpyrazine 93%
  • Liver 85%
  • Autophagy 69%
  • Hemorrhagic Shock 61%

• Study of Reactive Dicarbonyl Species-Induced Epithelial to Mesenchymal Transition in Diabetes Exacerbating Pulmonary Fibrosis

  Hsieh, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Fibrosis 100%
  • Epithelial-Mesenchymal Transition 90%
  • Pyruvaldehyde 66%
  • Receptor for Advanced Glycation End Products 34%
  • Glyoxal 32%

• 國際產學聯盟計畫III

  Lin, C.

  9/1/19 → 8/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Involvement of Il-21-Regulated Circulating Fibrocyte Activation in Chronic Obstructive Asthma( II )

  Hsieh, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用幹細胞及類器官技術剖析發炎性腸道疾病及消化道癌症的病理機轉並發展治療策略(2/3)

  Lee, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigate the New Therapeutic Strategy of Hinokitiol in Hepatic Ischemia/Reperfusion Injury( III )

  Lu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Anti-Neuroinflammatory Constituents from Fungal Species and Their Protective Profiles in the Retinal Diseases(2/3)

  Hsiao, G.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Pleiotropic Effects and Medical Therapy Strategy on Psoriasis

  Lee, A.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of 3d Air-Liquid-Interface Lung on Lab Chips for the Studies of Air-Pollution Induced Asthma and Lung Cancer with Immunotherapy

  Lee, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 科研創業計畫：監測血液免疫相合併智能演算預測CIK細胞抗癌療效

  Lin, C.

  1/1/22 → 12/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Alpha 9-Nicotinic Acetylcholine Receptor (Alpha 9-Nachr)-Mediated Trastuzumab (Herceptinr) Drug Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • MicroRNAs 66%
  • Trastuzumab 62%
  • CP 14 54%
  • Antineoplastic Agents 50%

• Study of Novel Genes Regulated by Aberrant DNA Methylation and Application in Colon Cancer Treatment

  Lin, R. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasm Genes 100%
  • Methylation 83%
  • Taiwan 82%
  • DNA Methylation 81%
  • Colonic Neoplasms 66%

• An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients

  Tu, S. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukocytes 100%
  • Tea 92%
  • Breast Neoplasms 87%
  • Nicotine 31%
  • Capsules 28%

• Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

  Wu, C. & Ho, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Breast Neoplasms 19%
  • Neoplasms 7%
  • Carcinogenesis 6%

• Identification and Characterization of Ddx3 Downstream Epithelial-Mesenchymal Transition (Emt) Targets in Colorectal Cancer Metastasis

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epithelial-Mesenchymal Transition 100%
  • Neoplasm Metastasis 95%
  • Colonic Neoplasms 87%
  • Snails 47%
  • RNA 40%

• Molecular Epidemiological Studies of Arsenical Skin Cancer: Effect of Gwas-Derived Snp Variants and Their Gene Expression on Cancer Risk

  Wu, M.

  8/1/18 → 7/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skin Neoplasms 100%
  • Arsenic 97%
  • Single Nucleotide Polymorphism 31%
  • Methylation 26%
  • Neoplasms 24%

• Investigation of the Role and Underlying Mechanism of Methylenetetrahydrofolate Dehydrogenase 2(Mthfd2) in the Cancer Stem Cell Properties and Tumorigenesis of Lung Cancer

  Deng, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methylenetetrahydrofolate Dehydrogenase (NADP) 100%
  • Neoplastic Stem Cells 29%
  • Lung Neoplasms 27%
  • NAD 21%
  • Serine 20%

• 產學合作計畫－開發農藥快篩之表面增強拉曼光譜之資料庫

  Liu, Y.

  6/1/20 → 5/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 產學合作計畫－抗藥性白色念珠菌單鏈抗體之研發

  Leu, S.

  11/1/20 → 10/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Ultrafine Particles on Cardiopulmonary System: a Population-Based Approach

  Chuang, K. & Feng, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Air Pollution 68%
  • Taiwan 34%
  • United States Environmental Protection Agency 33%
  • Organized Financing 13%

• 探討不同選擇作用之組織蛋白去乙醯酶調節成分抑制神經發炎之機制及其對腦內出血與腦炎之治療特性評估(1/3)

  Hsiao, G.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Gene Knock out Mice Model for Studying the Molecular Mechanisms of Early Onset Breast Tumor Microenvironment Regulation.

  Wu, C. & Tu, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antitumor 100%
  • Growth Factor 25%
  • Apoptotic 24%
  • Cell Death 23%
  • Hormone 21%

• Oxidative Damage in Retinal Pigment Epithelium---The Role Played by Mitochondria and the Protecting Effect of Mitochondria-Targeted Peptide Antioxidants

  Ho, J. & Hsieh, R.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • peptides 100%
  • mitochondria 86%
  • antioxidants 59%
  • toxicity 59%
  • oxidative stress 51%

• The Study of the Protective Effect of Far-Infrared-Improved Mitochondrial Function on Pancreatic Β-Cells in Diabetes Mice and Its Sirt1- and Plzf-Associated Mechanisms(2/3)

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Anti-Microglia/Macrophage Mechanisms of Different Tak1/Tabs Regulators and Their Protective Effects in Intracerebral Hemorrhage and Brain Abscess

  Hsiao, G.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphotransferases 100%
  • Cerebral Hemorrhage 52%
  • Brain Abscess 51%
  • Microglia 40%
  • Macrophage Activation 27%

• The Oncogenic Role and Targeted Therapeutic Potential of Alpha 9 Nicotinic Acetylcholine Receptors on Breast Cancers: Emphasizing in Pre-Clinical Assessment of Biphasic Antibody Nano-Drugs in Xenografts(II)(2/3)

  Chang, J.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Oncogenic Role and Targeted Therapeutic Potential of Alpha 9 Nicotinic Acetylcholine Receptors on Breast Cancers: Emphasizing in Pre-Clinical Assessment of Biphasic Antibody Nano-Drugs in Xenografts( III )

  Chang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫杉醇調控血小板活化、細胞凋亡和自我吞噬之分子機轉探討:體內及體外試驗(1/3)

  Lu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Tmu/Nih International Collaboration Study – Translational Research on Memory Reserve against Traumatic Brain Injury

  Chang, W.

  10/1/19 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Connectome 100%
  • Traumatic Brain Injury 77%
  • Memory 40%
  • Brain 31%
  • Animal Models 17%

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(1/3)

  Chen, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以多重反應監測質譜分析修格連氏症患者血清中之代謝體與其疾病之關聯性的探討

  Chang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers(2/3)

  Chan, W. P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Computer-Aided Peptide-Based Drug Design for Anticancer Peptide Prediction and Bioactivity Evaluation Based on Machine Learning Algorithms

  Su, E. C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting the Inflammation as a Novel Therapy for Neuroendocrine Prostate Cancer Determined by Zbtb46

  Chen, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sterile Alpha Motif 100%
  • Androgens 99%
  • Prostatic Neoplasms 98%
  • Androgen Receptors 83%
  • Transcription Factors 46%

• 建立傳染疾病的全球傳播風險預警架構：評估台灣與東亞區域的境外移入風險(2/2)

  Chuang, T.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討HMGB1對於DCLK1調控急性呼吸窘迫症候群之第二型肺泡上皮細胞老化之角色

  Lee, K.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Innovative Applications of Plasmon-Activated Water in Green Chemistry and Neuro-Related Medicine

  Liu, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Make a Portable/Wearable Kidney Possible – Development of Microtube Array Membrane (Mtam) Dialyzer – Study on Uremic Toxins Removal

  Wu, M.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Membranes 100%
  • Dialysis 95%
  • Equipment and Supplies 66%
  • Artificial Kidneys 55%
  • 4-cresol sulfate 34%

• Investigation the Functional Role of Extracellular Matrix Protein, Nephronectin, in the Renal Proximal Tubular Cell Tight Junction Formation

  Cheng, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • nephronectin 100%
  • Tight Junctions 31%
  • Renal Cell Carcinoma 30%
  • Neoplasm Metastasis 14%
  • Kidney 12%

• Mechanism of Evodiamine and Its Derivatives on Inhibition of Cddp Resistance and Epithelial-Mesenchymal Transition (Emt) of Human Ovarian Carcinoma Cells

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Clinically Applicable Lidocaine Concentration on Cancer Treatment: Auxiliary Impact during Hyperthermia/Chemotherapy and Perioperative Application

  Lin, J. A.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Arachidonate Metabolism in Determining Ying-Yang Effects of Sp1 on Drug Resistance in Glioblastoma and Lung Cancer( III )

  Chang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 創新電漿活化水製備表面增強拉曼散射活性基材(2/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Role of Podocalyxin-Like 1 in Regulation of Stemness and Metastasis of Breast Cancer and Cancer Stem Cells---Evaluation the Potentiality for Cancer Targeting Therapy

  Lin, C.

  1/1/13 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Mechanism of Post-Fracture Immune Dysfunction and the Role of Statin in Its Prevention and Treatment Strategy: from Bench to Bedside

  Lin, J. A.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Wounds and Injuries 100%
  • MicroRNAs 80%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 77%
  • 3' Untranslated Regions 65%
  • Immunosuppression 57%

• Study on the Mechanism Involved in Nanoparticles-Induced Tight Junction and Aquaporins Damages in Endothelial Cells, as Well as the Effects on Physiological Function of Endothelial Barriers

  Li, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanoparticles 100%
  • Blood-Brain Barrier 69%
  • Aquaporins 65%
  • Tight Junction Proteins 39%
  • Permeability 35%

• 交通空氣污染與健康成年人心血管健康效應之相關性研究

  Chuang, K.

  9/5/17 → 9/4/18

  Project: A - Government Institution › b - Ministry of Science and Technology