College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2027

• 2 Not started
• 100 Active
• 3607 Finished

Projects per year

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• b - National Science and Technology Council

  The Integrated Theraptic Effect of the Major Components of Psidium Guajava L. Aqueous Extracts (Pe) (Gallic Acid, Quercetin, Egcg, and Rutin) Combining with Medical Trials and Control Diets on the Chronic Kidney Disease

  Chen, K.-C. (PI)

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - National Science and Technology Council

  • Chronic Kidney Failure 100%
  • Quercetin 100%
  • Rutin 100%
  • Guava 100%
  • Gallic Acid 100%

• Association of Arsenic Exposure、Cigarette Smoking、Micrornas Expression and Urothelial Carcinoma

  Wu, C.-C. (PI)

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - National Science and Technology Council

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.-J. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• In Vi Vo and in Vi Tro Screening of the Dyslipidemic Antihypertensives, Studying the Mechanism to Modulate Signaling Srebp and Ppar in the Renal Cells, and Investigating the Cotherapy with Mountain Celery Seed Aqueous Extract in Reducing Worsen Renal F

  Chen, K.-C. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Celery 100%
  • Antihypertensive 100%
  • Kidney Injury 50%
  • Dyslipidemia 50%
  • Antihypertensive Agent 33%

• Urinary Total Arsenic Levels, Arsenic Methylation Capacity, Plasma Selenium Concentrations and Genetic Polymorphisms of Glutathione Peroxidase and Selenoprotein and Prostate Cancer

  Hsueh, Y.-M. (PI)

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - National Science and Technology Council

  • Genetic Polymorphism 100%
  • Glutathione Peroxidase 100%
  • Methylation 100%
  • Selenoprotein 100%
  • Selenium Blood Level 100%

• The Protective Effect of Plzf Nuclear Translocation against Advanced Glycation End Product-Induced Endothelial Injury in Diabetes and Its Molecular Mechanism

  Chen, C.-H. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Diabetes 100%
  • Endothelium Injury 100%
  • Zinc Finger and BTB Domain Containing Protein 16 100%
  • Advanced Glycation End-Product 100%
  • Advanced Glycation End Product 100%

• The Association between the Gene Polymorphisms and Plasma Concentration of Tissue Inhibitors of Metalloproteinase 3, Total Urinary Arsenic Concentration, Red Blood Cell Cadmium and Lead Levels, and Plasma Selenium Concentration and Chronic Kidney Disease

  Hsueh, Y.-M. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 探討Withaferin A對於香菸萃取物誘導小鼠肺上皮細胞氧化傷害與發炎反應之分子機轉

  Lee, K.-Y. (PI)

  7/1/23 → 2/29/24

  Project: A - Government Institution › b - National Science and Technology Council

• 絲氨酸蛋白酶抑制劑參與介白質6反式信令在氣喘患者呼吸道上皮細胞所造成的功能失常(1/3)

  Kuo, H.-P. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 建置轉譯導向婦癌生醫巨量資料庫開發精準醫療輔助系統(3/4)

  Chen, T.-H. (PI)

  5/1/23 → 4/30/24

  Project: A - Government Institution › b - National Science and Technology Council

• TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(3/3)

  Feng, P.-H. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Studies on the Signal Pathways of Caat/Enhancer Binding Protein Beta Mediate Thrombin-Induced Il-8/Cxcl8 Expression in Human Lung Epithelial Cells

  Chen, B.-C. (PI)

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - National Science and Technology Council

• Investigate the Biological and Prognostic Association of Annexin A2 in Nasopharyngeal Carcinoma

  Chen, C.-H. (PI) & Lee, F.-P. (CoI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Lipocortin 2 100%
  • Nasopharynx Carcinoma 100%
  • Radiation Therapy 16%
  • Chemotherapy 16%
  • Immunosuppressive Drug 8%

• Explore the Molecular Mechanisms and Application of microRNA-16 in In Acute Kidney Injury

  Chen, H.-H. (PI)

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - National Science and Technology Council

  • Creatinine Blood Level 100%
  • MicroRNA 100%
  • microRNA 16 100%
  • Acute Kidney Failure 100%
  • Lipocalin 50%

• Implantable Artificial Kidney Utilizing Nano-Porous Micro Tube Array Membrane Proof of Concept Study

  Wu, M.-S. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.-Y. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 科研創業計畫：回饋式呼吸引導暨預警系統-應用於遠距呼吸道復原照護

  Tseng, C.-H. (PI)

  7/1/21 → 6/30/22

  Project: A - Government Institution › b - National Science and Technology Council

• Investigate the Role and Effect of Pink1 in Lung Cancer Metabolism Regulation and Develop Pink1 Kinase Modulating Drugs for Lung Cancer Therapy.( III )

  Lin, E.P.-Y. (PI)

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - National Science and Technology Council

  • Drug Therapy for Lung Cancer 100%
  • Metabolic Regulation 100%
  • Lung Cancer 100%
  • Phosphotransferase 100%
  • Neurodegenerative Disorder 100%

• Exploring the Barriers and Overcome Strategies on the Way to Choosing Wisely (1/3)

  Chen, C. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of T Cell Exhaustion in Kidney Transplant

  Wu, M.-S. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Development, Validation, and Implementation of the Competency-Based Programs Evaluation (1/2)

  Chiu, H.-Y. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Seeking a Novel Therapeutic Strategy of Eya2/Brd4 Axis for the Treatment of Non-Small Cell Lung Cancer: Therapy for Drug Tolerant Persister Cells

  Kuo, K.-T. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 台灣智慧醫療聯盟主題式智慧醫材跨機構驗證及認證計畫

  Wu, M.-S. (PI)

  7/1/23 → 6/30/24

  Project: A - Government Institution › b - National Science and Technology Council

• Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs

  Hsieh, M.-H. (PI), Chen, Y.-J. (CoI) & Lin, Y.-K. (CoI)

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Heat Shock Protein 100%
  • Chronic Kidney Disease 100%
  • Kidney Injury 100%
  • Chronic Kidney Failure 100%
  • Atrial Fibrillation 100%

• Effects of Resveratrol Supplementation on Endurance Performance, Oxidative Stress and Inflammation

  Hsu, C.-C. (PI)

  8/1/11 → 12/31/12

  Project: A - Government Institution › b - National Science and Technology Council

  • Resveratrol 100%
  • Oxidative Stress 100%
  • Inflammation 100%
  • Placebo 50%
  • Antioxidant 50%

• Studies on the Anti-Tumor Effects of Receptor-Specific-Rna Aptamer-Derived Nanoparticles Induced Type-3 Hyaluronan Synthase Activation in Breast Carcinogenesis

  Tu, S.-H. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• Case Control Longitudinal Study of Romosozumab Vs. Denosozumab Treatment for Osteoporotic Women in Assessment of Hrct-Based Vertebral Structural Changes (1/3)

  Chan, W. P. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Mechanistic Insight of Pcsk9 Suppression on Atrial Fibrosis with Direct Anti-Fibrotic Activity: a Novel Therapeutic Strategy for Atrial Myopathy and Arrhythmogenesis.

  Chung, C.-C. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Beta-3 Adrenergic Signaling on Ventricular Arrhythmogenesis: Insights from Cardiac Metabolism, Oxidative Stress and Ca2+ Homeostasis in Right Ventricular Outflow Tract Cardiomyocytes

  Hsieh, M.-H. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• 以Sirtuin 1 和 Klotho的交叉調節作為減少主動脈瓣膜鈣化的治療策略

  Li, S.-J. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• 以任意多焦點空間光調製技術整合低能量雷射光源發展具備抑制神經纖維瘤增生的高精準度光處方光動力療法系統

  Chang, C.-J. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• The Mechanisms of Periodontal Pathogen Aggravating the Formation of Abdominal Aortic Aneurysm and the Development of Targeting Therapy

  Lin, F.-Y. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Effects of Regular Exercise on Learning and Memory Function in Aged Hyperlipidemia: an Analysis by Behavioral, Cell Physiological, and Molecular Biological Correlate

  Hsu, C.-C. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• 探討缺氧環境對Yap/Taz調控胚胎肺部之分枝與型態:纖維母細胞所扮演的角色

  Lee, K.-Y. (PI)

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - National Science and Technology Council

• The Investigation of the Protective Effect of the Ethanol Extract from Brown Seaweed Laminaria Japonica on Chronic Kidney Disease and Its Molecular Mechanism

  Chen, T.-H. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Chronic Kidney Failure 100%
  • Laminaria japonica 100%
  • Algal Extract 66%
  • Fucoxanthin 58%
  • Peroxisome Proliferator Activated Receptor 25%

• 標定能量代謝與粒線體功能調控:維生素D於心肌胰島素阻抗的治療潛力

  Lee, T.-W. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council

• Molecular Mechanisms of Helicobacter Pylori Virulence Factors for Regulating Inflammation Responses in Epithelial Cells and Macrophages

  Lin, H.-J. (PI)

  4/1/11 → 7/31/11

  Project: A - Government Institution › b - National Science and Technology Council

  • Pylorus 100%
  • Inflammation Response 100%
  • Macrophage 100%
  • Virulence Factor 100%
  • Helicobacter Pylori 100%

• The Immunomodulatory Role of Melatonin in Promoting the Progression of Graves' Disease

  Lin, J.-D. (PI)

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - National Science and Technology Council

  • Graves' Disease 100%
  • Melatonin 100%
  • Graves Disease 100%
  • Thyroid 61%
  • Thyrotropin Receptor 23%

• Analyze Exhaled Gas of COPD Patients ( II )

  Shih, C.-H. (PI)

  5/1/15 → 4/30/16

  Project: A - Government Institution › b - National Science and Technology Council

  • Disease Patient 100%
  • System-on-Chip 100%
  • Electronic Nose 100%
  • Gas Chromatography Mass Spectrometry 100%
  • Scalability 100%

• The Study of the Protective Effect of Far-Infrared-Improved Mitochondrial Function on Pancreatic Β-Cells in Diabetes Mice and Its Sirt1- and Plzf-Associated Mechanisms

  Chen, C.-H. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

• Investigation of the Role of Btk in Drug Resistant Lung Cancer and Development of New Treatment Strategy

  Kuo, K.-T. (PI)

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - National Science and Technology Council

  • Lung Development 100%
  • Lung Cancer 100%
  • Bruton Tyrosine Kinase 100%
  • Cancer Cell 33%
  • Neoplasm 26%

• Statin Inhibits Pressured-Induced Rat Renal Tubular Cell Apoptosis and Tubulointerstitial Fibrosis

  Chen, T.-H. (PI) & Chen, C.-H. (CoI)

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - National Science and Technology Council

  • Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor 100%
  • Statin (Protein) 100%
  • Fibrosis 100%
  • Peroxisome Proliferator Activated Receptor 57%
  • Injury 42%

• 長散在核元件-1甲基化及DNA甲基化標記5-甲基胞嘧啶與5-甲基-2'-脫氧胞?濃度及尿液總砷濃度與慢性腎臟病的相關性

  Hsueh, Y.-M. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• The Role of Endothelial Β-Catenin Activation in Arteriovenous Fistula Intimal Lesions

  Sue, Y.-M. (PI)

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - National Science and Technology Council

• The Pathogenic Role of Ifn-Alpha in a Spontaneous Hashimoto'S Thyroiditis Mouse Model

  Lin, J.-D. (PI)

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - National Science and Technology Council

• Planning and Promotion of the Research in Pulmonology

  Lee, K.-Y. (PI)

  1/1/22 → 12/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Estimating the Therapeutic Effectiveness of Targeting Nicotinic Acetylcholine Receptor 5-Foxd1 Signaling Axis on Suppressing the Radiation Resistance and Immune Evasion of Oral Cancer

  Lin, C.-H. (PI)

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - National Science and Technology Council

• Serum Translocator Protein (Tspo) as Biomarker of Brain Damage in Cognitive Ability and the Related Association with Neuro-Inflammation.

  Bai, C.-H. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• Rescuing Chemotherapy-Induced Epigenetic Alterations in Cancer Fibroblasts as a Novel Therapeutic Strategy in Advanced Pancreatic Ductal Adenocarcinoma (1/3)

  Lee, T.-I. (PI)

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - National Science and Technology Council

• 探討AIM2發炎小體促進肺腺癌轉移與免疫抑制的分子機制與其相關轉譯醫學應用(1/3)

  Zheng, J.-Q. (PI)

  8/1/23 → 7/31/24

  Project: A - Government Institution › b - National Science and Technology Council