College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 245 Active
• 3059 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  Investigation of Nuclear microRNA Signatures and Their Functional Effects on Glioblastoma Multiforme Pathology

  Chen, K. & Shih, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Glioma 23%
  • Genes 12%

• Explore the Molecular Mechanisms and Application of microRNA-16 in In Acute Kidney Injury

  Chen, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acute Kidney Injury 100%
  • Biomarkers 15%
  • MicroRNAs 9%
  • Creatinine 9%
  • Kidney Function Tests 9%

• Characterization of Molecular and Pathological Role of Hs 1-Associated Protein X-1(Hax-1) in Cisplatin Induced Nephorotoxicity via Hax-1 Conditional Knock out Mice

  Lin, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cisplatin 100%
  • Kidney 45%
  • Knockout Mice 31%
  • Renal Insufficiency 22%
  • Wounds and Injuries 16%

• Use of Microrna-328-5p/6885-5p as Diagnostic and Therapeutics Targets for Contrast Induced Nephropathy(2/3)

  Chen, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 配對式神經調控模式應用於脊髓損傷者之前瞻神經復健技術開發-子計畫一: 在脊髓損傷動物模式下探討配對式神經調控之作用機制與療效(2/3)

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms of Empaglifozin on Cardiac Metabolism with Electrical and Structural Remodelings: Implications in Cardio-Protection of Sodium Glucose Transporter 2 Inhibitor

  Lee, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • empagliflozin 100%
  • Diabetes Mellitus 36%
  • Sodium-Glucose Transporter 2 Inhibitors 31%
  • Peroxisome Proliferator-Activated Receptors 21%
  • Cardiomyopathies 20%

• The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)

  Chien, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Jet Lag as a Potent Manipulator of Mood

  Myung, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Artificial Intelligence for Earlier and Safer Medicine Worldwide(2/4)

  Li, Y.

  1/1/19 → 10/8/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用Iodoacetamide衍生物找尋與鑑定新型藥物標靶用於治療多型性神經膠質母細胞瘤

  Lin, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Prp: Platelet-Rich Plasma Effects in the Articular Chondrocytes and Synovial Fibroblasts with the Associated Mechanism---A Fibronectin Fragment Model

  Lee, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • Toll-like receptor 2 91%
  • cartilage 74%
  • growth factors 68%
  • chondrocytes 66%

• Inflammatory Regulation by Circulating Haptoglobin 2-2 in the Severity of Chronic Obstructive Pulmonary Disease

  Ho, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Haptoglobins 100%
  • Chronic Obstructive Pulmonary Disease 64%
  • Phenotype 32%
  • Lung 13%
  • Lung Injury 12%

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma---The Treatment of Metastatic Cancer

  Chien, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • MicroRNA 72%
  • Microarrays 10%
  • Non Toxic 10%
  • Dose 7%

• The Machnism of Calcium Containing Cystals in Bone Remodeling

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bones 100%
  • osteoclasts 77%
  • arthritis 67%
  • osteoblasts 43%
  • calcium 31%

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma: the Treatment of Metastatic Cancer

  Chien, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Use of Microrna-328-5p/6885-5p as Diagnostic and Therapeutics Targets for Contrast Induced Nephropathy.

  Chen, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Translational Study to Verify Roles of Circulating Mir-19b and Mir-93 as Biomarker Signatures for Early Diagnosis of Osteoporosis in Men

  Chen, R.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 電子書於熟齡族群醫學教育推廣之成效評估—以肝臟為例

  Chen, S.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of C/EBP-Β Regulates microRNA-16 and Its Clinical Application(2/2)

  Chen, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 78%
  • Transcription Factors 68%
  • Reperfusion Injury 17%
  • Kidney 14%

• Evaluate the Molecluar Mechanims and Clinical Application on Atf3 Regulated microRNAs

  Lin, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 43%
  • Kidney 29%
  • Biomarkers 17%
  • Activating Transcription Factor 3 14%

• Studies on the Potential Antitumor Mechanisms of Hyaluronan Synthase Involved in Early Onset Breast Tumor Tissues

  Tu, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Hyaluronan Synthases 43%
  • Hyaluronic Acid 23%
  • Neoplasms 19%
  • Knockout Mice 10%

• Therapeutic Potentials of Peptide-Based Cytokine Binding Decoy against Sepsis and Its Effects on Modulating Inflammation, Oxidation, Apoptosis, Autophagy and Inflammasome

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sepsis 100%
  • Peptides 37%
  • Cytokine Receptors 31%
  • Cytokines 24%
  • Inflammasomes 23%

• Using Data Mining Techniques to Build Risk Assessment Models for Postoperative and Long-Term Complications in Patients with Chronic Kidney Disease

  Lin, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of C/EBP-Β Regulates microRNA-16 and Its Clinical Application

  Chen, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 78%
  • Transcription Factors 68%
  • Reperfusion Injury 17%
  • Kidney 14%

• Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring

  Chen, C. & Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fetal Growth Retardation 100%
  • Hyperoxia 99%
  • Receptor for Advanced Glycation End Products 74%
  • Epigenomics 69%
  • Lung 48%

• 探討黃腐醇合併降血糖藥是否可調控粒線體失常並經由活化未摺疊蛋白反應所激發之AMPK-NRf2-ARE-Glo1路徑來逆轉雙羰基壓力導致之糖尿病腎脂毒性

  Chen, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Molecular Mechanism of Pparα in Acute Kidney Injury: Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPAR alpha 100%
  • MicroRNAs 59%
  • Type C Phospholipases 43%
  • Kidney 33%
  • Acute Kidney Injury 22%

• The Protective Effect of Plzf and Annexin A1 on Diabetic Tubulopathy in the Pparα Signaling Pathway

  Hsu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPAR alpha 100%
  • Promyelocytic Leukemia Zinc Finger Protein 66%
  • Annexin A1 54%
  • Kidney 39%
  • Autophagy 25%

• Dissected the Role of Thrombomodulin in the Clinical Diagnostic and Therapeutic Impacts for Breast Cancer and the Regulation Mechanisms(3/3)

  Hung, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thrombomodulin 100%
  • Breast Neoplasms 90%
  • Therapeutics 20%
  • Neoplasms 12%
  • Steroid Receptors 11%

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma(3/3)

  Chien, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• The Integrated Theraptic Effect of the Major Components of Psidium Guajava L. Aqueous Extracts (Pe) (Gallic Acid, Quercetin, Egcg, and Rutin) Combining with Medical Trials and Control Diets on the Chronic Kidney Disease

  Chen, K.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Complementary Therapies 100%
  • Chronic Renal Insufficiency 82%
  • Gallic Acid 55%
  • Psidium 26%
  • Diet 22%

• Identification of Roles of microRNAs in Drug Resistance Development of Chronic Myeloid Leukemia

  Shih, C. & Liu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 87%
  • Drug Resistance 40%
  • Imatinib Mesylate 29%
  • ran GTP-Binding Protein 29%

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Prevention, Control, Genotyping and Risk Factors of Intestinal Parasitic Infections and Head Lice in Schoolchildren in Cambodia(2/3)

  Liao, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Utilizing Artificial Intelligence Vi Rtual Screening Platform to Identify a Small-Molecule Inhibitor of Dna Polymerase Theta and Estimating Its Therapeutic Effectiveness on Metastatic Castration-Resistant Prostate Cancer

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用人工智慧虛擬篩選平台鑑定DNA聚合酶theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(3/3)

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 透過in silico virtual docking從現有藥物中篩選干擾 Spike protein 及 ACE2 結合之治療COVID-19潛力藥物

  Yang, C. H.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Postoperative Adverse Outcomes of Surgical Patients Using Taiwan National Health Insurance Database

  Chen, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Anesthesia 100%
  • Postoperative Complications 87%
  • Databases 61%
  • National Health Programs 53%
  • Taiwan 50%

• Exploring the Potential Impacts of Maternal Early-Life Sleep Deprivation on Metabolic Function of the Offspring( II )

  Chang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Scaffold in Ovarian Transplantation for Female Fertility Preservation: an in vivo Transgenic Mouse Model (II)

  Chen, C., Tzeng, C. & Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sphingosine 100%
  • vascular endothelial growth factors 67%
  • phosphates 52%
  • female fertility 30%
  • autografting 18%

• Study the mutation gene of familial lymphedema in zebrafish model

  Cheng, C.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Potential Application of a Natural Compound, Tripolate, for Enhancing the Therapeutic Efficacy of Sorafenib in Hepatic Cancer

  Chen, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development---How Is Paternal Psychopathology Involved?

  Chen, Y., Hsu, C., Lin, H. & Huang, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mothers 100%
  • Psychopathology 77%
  • Newborn Infant 75%
  • Spouses 59%
  • Pregnancy Outcome 59%

• Graft Force and Pressure on Graft over Tibial Tunnels in Pcl Reconstruction

  Chuang, T. & Ho, W.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • posterior cruciate ligament 100%
  • tendons 18%
  • thighs 12%
  • surgeons 12%
  • orthopedics 12%

• Electroacupunture Relieves Pelvic Pain by Antagonizing Mecp2-Dependent Epigenic Modification of Bdnf Mediates Estrogen-Fasciliated Uterus-Colon Crosstalk in Rats

  Lin, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methyl-CpG-Binding Protein 2 100%
  • Urethra 61%
  • Brain-Derived Neurotrophic Factor 59%
  • Colon 49%
  • Histones 39%

• Development of efficient immunoglobulin G analytical method for investigating autoantibody biomarkers for pancreatic disease

  Tsai, I.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishing A Translational Female Cancer Biomedical Big Data Bank and Developing Precision Medicine Healthcare System( I )

  Chen, T.

  5/1/21 → 4/30/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討慢性睡眠剝奪對口腔菌叢的影響，並闡明口腔菌叢引致認知功能失常的潛在機制

  Chang, H.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Par-Pcp Signaling in Invasive-Cancer-Stem-Cell-Mediated Metastasis and Its Therapeutic Targeting(1/3)

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology