College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 245 Active
• 3059 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  BSP相似重複序列家族蛋白在草綠色鏈球菌所引起的感染性心內膜炎中細菌逃避免疫攻擊及生物膜形成所扮演的角色及機制探討(3/3)

  Jung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Cellular and Molecular Mechanisms of Nicotine and Nitrosamines Promote Tumorigenic Behaviors in Renal Cell Carcinoma (Ii)

  Cheng, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Nanocarriers for Drug Delivery Conjugated with Specific Aptamer for Potential Use in Membranous Nephropathy

  Lin, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • Membranous Glomerulonephritis 99%
  • Phospholipase A2 Receptors 94%
  • Nanoparticles 88%
  • Inflammasomes 85%

• Investigation on the Improvenment of Solanum Nigrum and Paris Polyphylla for Inhibitions of Metastasis and Drug Resistance Mediated by Exosomes from Breast Cancer Cells

  Tai, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Drug 100%
  • Antineoplastic Agent 84%
  • Marker 83%
  • MicroRNA 58%
  • Protein 19%

• A Large Series of Clinical and Imaging Investigation to Patients with Chronic Lower Limb Edema with Unclear Etiology

  Chan, W. P.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phlebography 100%
  • Edema 47%
  • Lower Extremity 36%
  • Angiography 15%
  • Leg 10%

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功 能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(1/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 創新電漿活化水製備表面增強拉曼散射活性基材(3/3)

  Liu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Evaluate the Pharmacological Mechanisms of Novel Natural Plant Extracts of Coumarins in Suppressing Angiogenesis, Lymphangiogenesis and Inflammation

  Hsu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Novel Activities of Gamma-Aminobutyric Acid-Mediated Regulation of Platelet Activation, Apoptosis, and Autophagy: the Non-Genomic Functions of Nf-Kappab Signal in Anucleated Cells

  Sheu, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • gamma-Aminobutyric Acid 100%
  • Blood Platelets 65%
  • Platelet Activation 27%
  • Mitochondrial DNA 26%
  • Autophagy 20%

• Study on the Pathophysiological Importance of Txnip in Cigarette Smoke-Caused Pulmonary Inflammation and Chronic Obstructive Pulmonary Disease

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thioredoxins 100%
  • Smoke 53%
  • Tobacco Products 52%
  • Chronic Obstructive Pulmonary Disease 45%
  • Pneumonia 30%

• BSP相似重複序列家族蛋白在草綠色鏈球菌所引起的感染性心內膜炎中細菌逃避免疫攻擊及生物膜形成所扮演的角色及機制探討(2/3)

  Jung, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Influence of Porphyromonas gingivalis Groel in Vascular Cells

  Lin, F.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Porphyromonas gingivalis 100%
  • blood vessels 46%
  • myocytes 40%
  • smooth muscle 39%
  • atherosclerosis 36%

• Molecular Mechanism in Amyloid Peptide-Induced Cerebral Endothelial Cell Apoptosis:Role of Hdac and Ampk

  Hsu, M.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylation 100%
  • Histone Deacetylases 95%
  • Endothelial Cells 60%
  • Cerebral Amyloid Angiopathy 57%
  • Sirtuins 55%

• 糖尿病與巴金森症之風險: 探討胰島素阻抗與巴金森症機轉之關聯

  Hong, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(2/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 吳茱萸生物鹼rutaecarpine調控血小板活化及自噬作用的機轉探討以及在自體血栓塊引起腦中風鼠的活性評估: NF-kB在無核細胞中的角色(2/3)

  Sheu, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• β-catenin訊息路徑誘發動靜脈廔管病變之分子機轉: 預防動靜脈廔管狹窄之新型治療標的 (第二年延續計畫)

  Sue, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers

  Chan, W. P.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Service for Sharing Precious Instruments of Taipei Medical University

  Lin, C.

  1/1/13 → 1/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以全結構去細胞方式進行氣管移植與取代的組織工程置換物之嘗試(2/2)

  Hung, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • trachea (vertebrates) 100%
  • cartilage 77%
  • sonication 70%
  • tissues 27%
  • skeleton 25%

• Study on the Regulation of Txnip in Nicotine-Induced Inflammatory C-Reactive Protein Expression in Macrophages and Its Pathological Effects

  Chen, C.

  2/1/16 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nicotine 100%
  • Thioredoxins 91%
  • C-Reactive Protein 64%
  • NADPH Oxidases 38%
  • Macrophages 27%

• 重點產業高階人才培訓與就業計畫

  Lin, C.

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(3/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Effects and Underlying Mechanisms of B Type Natriuretic Peptide in Endothelial-Mesenchymal Transition: a Study Regarding to Cardiac Allograft Vasculopathy

  Lin, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain Natriuretic Peptide 100%
  • Thrombomodulin 99%
  • Endothelial Progenitor Cells 55%
  • Allografts 52%
  • Tissue Donors 47%

• Efficacy Studies of Tn-Directed Therapeutic Antibody and Immunotoxin in Syngeneic Mouse Tumor Models

  Hwang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • antibodies 100%
  • mice 94%
  • prostatic neoplasms 51%
  • neoplasms 48%
  • vaccines 21%

• Autolysin regulatory machinery of Streptococcus mutans in bacterial survival and biofilm formation in infective endocarditis

  Jung, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endocarditis 100%
  • Streptococcus mutans 24%
  • Ions 22%
  • N-Acetylmuramoyl-L-alanine Amidase 20%
  • Biofilms 20%

• 110年度產業高階人才培訓計畫

  Lin, C.

  5/1/21 → 4/30/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 吳茱萸生物鹼rutaecarpine調控血小板活化及自噬作用的機轉探討以及在自體血栓塊引起腦中風鼠的活性評估: NF-kB在無核細胞中的角色(3/3)

  Sheu, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討戈登鏈球菌VicR調控蛋白質在細菌與血小板交互作用中扮演的角色

  Jung, C.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Translational Investigation of the Role of Myc/Pd-L1/Akt Axis as a Therapeutic Target for Treating Glioblastoma Multiforme

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 競爭性內源RNA-BC200調控網絡誘導腦瘤中嘌呤體形成之分子機制與臨床意義

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Reactive Dicarbonyl Species-Induced Epithelial to Mesenchymal Transition in Diabetes Exacerbating Pulmonary Fibrosis (Ii)－Clarification of Age/Rage-Independent Pathways and Analysis of Correlation with Clinical Outcome

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Fibrosis 100%
  • Epithelial-Mesenchymal Transition 72%
  • Pyruvaldehyde 49%
  • Receptor for Advanced Glycation End Products 30%
  • Glyoxal 27%

• 氧化還原作用調控蛋白質去磷酸酉每羰基化和去羰基化反應對動脈血管內膜增生之影響(1/2)

  Hsieh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of VEGF Isoform Change in Progressive Renal Fibrosis

  Chang, F.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Microvascular Rarefaction 100%
  • Vascular Endothelial Growth Factor A 96%
  • Kidney 93%
  • Pericytes 76%
  • Protein Isoforms 60%

• Study of Reactive Dicarbonyl Species-Induced Epithelial to Mesenchymal Transition in Diabetes Exacerbating Pulmonary Fibrosis (Ii)－Clarification of Age/Rage-Independent Pathways and Analysis of Correlation with Clinical Outcome(2/2)

  Hsieh, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Fibrosis 100%
  • Epithelial-Mesenchymal Transition 72%
  • Pyruvaldehyde 49%
  • Receptor for Advanced Glycation End Products 30%
  • Glyoxal 27%

• Using Arterial Spin Labeled Magnetic Resonance Imaging (Asl-Mri) to Evaluate Cerebral Blood Flow Changes in Patients with Chronic Kidney Disease(2/2)

  Liu, H.

  8/1/18 → 10/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Cerebrovascular Circulation 49%
  • Gadolinium 31%
  • Kidney 31%
  • Brain 28%

• The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (II)

  Lin, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Glioblastoma Using Advanced Multimodal Small Animal Mr Imaging Techniques

  Liu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制PCSK9對於改善心房纖維化之機轉以及治療心房纖維化引發心律不整治療之創新應用研究。(3/3)

  Chung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Computer-Aided Peptide-Based Drug Design for Anticancer Peptide Prediction and Bioactivity Evaluation Based on Machine Learning Algorithms

  Su, E. C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺纖維化之分子病理機制探討-探討Sema7A+調節型T細胞在肺部纖維化中第二型免疫反應的調控角色(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Explore the Influence of Chlamydia Pneumoniae Groel in Endothelial Progenitor Cells.

  Lin, F.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chlamydophila pneumoniae 100%
  • Endothelial Progenitor Cells 46%
  • Pneumonia 30%

• The Roles of Tgf-B Signal and Inflammatory Cells in Mfs Patients and the Possible Correlation between Marfan Syndrome and Autoimmune Disease

  Chiu, H.

  9/1/12 → 12/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Marfan Syndrome 100%
  • Transforming Growth Factors 47%
  • Autoimmune Diseases 39%
  • T-Lymphocytes 24%
  • Regulatory T-Lymphocytes 19%

• 創新電漿活化水製備表面增強拉曼散射活性基材(2/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Lipoprotein on the Endothelial-To-Mesenchymal Transition Process of Mature Endothelial Cell and Endothelial Progenitor Cells in Vessel Neo-Intimal Formation

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • erucylphosphocholine 100%
  • HDL Lipoproteins 96%
  • oxidized low density lipoprotein 25%
  • Dyslipidemias 16%
  • Atherosclerosis 13%

• Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice

  Lee, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Volatile Fatty Acids 100%
  • Phenylbutyrates 27%
  • Mast Cells 25%
  • Immunoglobulin E 19%
  • Asthma 16%

• Study on the Mechanism Involved in Nanoparticles-Induced Tight Junction and Aquaporins Damages in Endothelial Cells, as Well as the Effects on Physiological Function of Endothelial Barriers

  Li, C. & Cheng, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanoparticles 100%
  • Blood-Brain Barrier 69%
  • Aquaporins 65%
  • Tight Junction Proteins 39%
  • Permeability 35%

• Application and Mechanism of Novel Fluoro-Rutaecarpine on Inhibition of Inflammation Induced Endomt

  Lin, C.

  8/1/14 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibrosis 19%
  • Inflammation 15%
  • Sumoylation 5%

• Aldose Reductase and Nf-Κb Signalings in Collagen Receptor Glycoprotein Vi-Mediated Platelet Autophagy: a Regulatory Mechinary of Endogenous Gaba in Anucleate Blood Cells (II)

  Sheu, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Aldose Reductase and Nf-Kb Signalings in Collagen Receptor Glycoprotein Vi-Mediated Platelet Autophagy: a Regulatory Mechinary of Endogenous Gaba in Anucleate Blood Cells

  Sheu, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autophagy 100%
  • Blood Platelets 64%
  • Aldehyde Reductase 63%
  • gamma-Aminobutyric Acid 33%
  • convulxin 30%